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- Volume 16, Issue 2, 2022
Recent Advances in Drug Delivery and Formulation - Volume 16, Issue 2, 2022
Volume 16, Issue 2, 2022
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ROS Modulating Inorganic Nanoparticles: A Novel Cancer Therapeutic Tool
Authors: Maria J. N. Amaldoss and Charles C. SorrellThe term "reactive oxygen species" (ROS) refers to a family of extremely reactive molecules. They are crucial as secondary messengers in both physiological functioning and the development of cancer. Tumors have developed the ability to survive at elevated ROS levels with significantly higher H2O2 levels than normal tissues. Chemodynamic therapy is a novel approach to cancer treatment that generates highly toxic hy Read More
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Drug Delivery Platforms Containing Thermoresponsive Polymers and Mucoadhesive Cellulose Derivatives: A Review of Patents
Nowadays, the development of mucoadhesive systems for drug delivery has gained keen interest, with enormous potential in applications through different routes. Mucoadhesion characterizes an attractive interaction between the pharmaceutical dosage form and the mucosal surface. Many polymers have shown the ability to interact with mucus, increasing the residence time of local and/or systemic administered preparation Read More
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Recent Patents on Nasal Vaccines Containing Nanoadjuvants
Authors: Francesco Candela, Eride Quarta, Francesca Buttini, Adolfo Ancona, Ruggero Bettini and Fabio SonvicoVaccines are one of the greatest medical achievements of modern medicine. The nasal mucosa represents an effective route of vaccination for both mucosal immunity and peripheral, being at the same time an inductive and effector site of immunity. In this paper, the innovative and patented compositions and manufacturing procedures of nanomaterials have been studied using the peerreviewed research literature. Read More
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Optimizing and Evaluating the Transdermal Permeation of Hydrocortisone Transfersomes Formulation Based on Digital Analysis of the In Vitro Drug Release and Ex Vivo Studies
Authors: Asmae Abdelwahd and Bazigha K. Abdul RasoolBackground: Transfersomes can be used to enhance transdermal drug delivery due to their flexibility and ability to incorporate various molecules. For example, hydrocortisone (HC), a corticosteroid, is taken by different routes and serves as immunosuppressive, anticancer, and antiallergenic; however, it is poorly absorbed by the skin. Objective: Therefore, the current study suggested HC-loaded transfersomes as an alternative Read More
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Exploring the Patent Landscape and Innovation of Hydrogel-based Bioinks Used for 3D Bioprinting
By Ahmed FatimiBackground: This paper provides a comprehensive overview of the patent situation for hydrogel- based bioinks used for 3D bioprinting globally. It encapsulates information which could be used as a reference by researchers in the fields of 3D bioprinting, biomaterials, tissue engineering, and biomedical engineering, as well as those interested in biomaterials, especially in the formulation of hydrogels. It can also inform policy di Read More
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