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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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A Docking Modelling Rationally Predicts Strong Binding of Bisphenol A to Estrogen-Related Receptor γ
- Source: Protein and Peptide Letters, Volume 15, Issue 3, Mar 2008, p. 290 - 296
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- 01 Mar 2008
Abstract
A computer-aided docking study was carried out to quickly clarify the binding structure of the ligand-receptor complex between bisphenol A (BPA), a well-known endocrine disruptor, and estrogen-related receptor γ (ERRγ). The resulting complex indicated that BPA binds to the ligand-binding pocket of ERRγ without any disruptions of the activation conformation.
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