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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Spectroscopic and Functional Characterization of Human β-Synuclein
- Source: Protein and Peptide Letters, Volume 14, Issue 10, Oct 2007, p. 1021 - 1026
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- 01 Oct 2007
Abstract
To elucidate potential biological roles of human β-synuclein, we studied its conformational changes under various conditions. The structural and functional properties of β-synuclein were characterized using biochemical and biophysical methods including: a functional assay, mass spectrometry, size exclusion chromatography, circular dichroism (CD), and fluorescence spectroscopy. The results showed β-synuclein has a high proportion of random coil in solution.
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