The Blomia tropicalis Allergens

Kaw Yan Chua; Nge Cheong; I-Chun Kuo; Bee Wah Lee; Fong Cheng Yi; Chiung-Hui Huang; Lip Nyin Liew

doi:10.2174/092986607780363862

ISSN: 0929-8665
E-ISSN: 1875-5305

The Blomia tropicalis Allergens
Authors: Kaw Yan Chua¹, Nge Cheong², I-Chun Kuo³, Bee Wah Lee⁴, Fong Cheng Yi⁵, Chiung-Hui Huang⁶ and Lip Nyin Liew⁷
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¹ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ² Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ³ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ⁴ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ⁵ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ⁶ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074. ⁷ Department of Paediatrics,Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074.
Source: Protein and Peptide Letters, Volume 14, Issue 4, Apr 2007, p. 325 - 333
DOI: https://doi.org/10.2174/092986607780363862
- Available online: 01 Apr 2007

Abstract

Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity.

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2007-04-01

2025-05-27

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Article Type: Research Article

Keyword(s): cysteine protease; Dermatophagoides; house dust mite allergens; IgE; RACE cDNA amplification

The Blomia tropicalis Allergens

Abstract

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