Oligomerisation of Sarcoplasmic Reticulum Ca2+-ATPase Monomers from Skeletal Muscle

Daniela Schreiber; Kay Ohlendieck

doi:10.2174/092986607780090838

ISSN: 0929-8665
E-ISSN: 1875-5305

Oligomerisation of Sarcoplasmic Reticulum Ca2+-ATPase Monomers from Skeletal Muscle
Authors: Daniela Schreiber¹ and Kay Ohlendieck²
View Affiliations Hide Affiliations

¹ Department of Biology, National University of Ireland, Maynooth, Co. Kildare, Ireland. ² Department of Biology, National University of Ireland, Maynooth, Co. Kildare, Ireland.
Source: Protein and Peptide Letters, Volume 14, Issue 3, Mar 2007, p. 219 - 226
DOI: https://doi.org/10.2174/092986607780090838
- Available online: 01 Mar 2007

Abstract

The fast-twitch SERCA1 isoform of the sarcoplasmic reticulum Ca2+-ATPase was purified to homogeneity and conjugated to peroxidase. The SERCA1 probe showed high affinity binding to the immobilized monomeric enzyme, but not crosslinker-stabilized oligomers. This suggests a preferential complex formation via homo-dimerization, rather than interactions with established oligomeric structures.

Article metrics loading...

/content/journals/ppl/10.2174/092986607780090838

2007-03-01

2025-05-22

From This Site

/content/journals/ppl/10.2174/092986607780090838

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/ppl/10.2174/092986607780090838

Article Type: Research Article

Keyword(s): Blot overlay; Ca2+-ATPase; Ca2+-uptake; oligomerisation; sarcoplasmic reticulum; SERCA

Oligomerisation of Sarcoplasmic Reticulum Ca2+-ATPase Monomers from Skeletal Muscle

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

The LL-37 Antimicrobial Peptide as a Treatment for Systematic Infection of Acinetobacter baumannii in a Mouse Model

FN1 Promotes Thyroid Carcinoma Cell Proliferation and Metastasis by Activating the NF-b Pathway

Wogonin Restrains the Malignant Progression of Lung Cancer Through Modulating MMP1 and PI3K/AKT Signaling Pathway

A Temporin Derived Peptide Showing Antibacterial and Antibiofilm Activities against Staphylococcus aureus

Upregulation of Connexins in the Rat Hippocampal and Cortical Neurons Following Blockade of NMDA Receptors During Postnatal Development

Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway

Protease Inhibitors (PIs): Candidate Molecules for Crop Protection Formulations against Necrotrophs

Preparation of IgE Antibody and Distribution of IgE⁺ Secretory Cells in the Palatine Tonsil of Bactrian Camel

Different VH3-binding Protein A Resins Show Comparable VH3-binding Mediated Byproduct Separation Capabilities Despite Having Varied Dynamic Binding Capacities Towards A VH3 Fab

Immunogenicity and Neutralization Potential of Recombinant Chimeric Protein Comprising the Catalytic Region of Gp63 of Leishmania and LTB against Leishmania donovani