Design and Synthesis of Metal-Free Artificial Ribonucleases

Ludmila S. Koroleva; Inna Yu. Serpokrylova; Valentin V. Vlassov; Vladimir N. Silnikov

doi:10.2174/092986607779816177

ISSN: 0929-8665
E-ISSN: 1875-5305

Design and Synthesis of Metal-Free Artificial Ribonucleases
Authors: Ludmila S. Koroleva¹, Inna Yu. Serpokrylova², Valentin V. Vlassov³ and Vladimir N. Silnikov⁴
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¹ Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentiev prosp., Novosibirsk, 630090,Russia. ² Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentiev prosp., Novosibirsk, 630090,Russia. ³ Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentiev prosp., Novosibirsk, 630090,Russia. ⁴ Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentiev prosp., Novosibirsk, 630090,Russia.
Source: Protein and Peptide Letters, Volume 14, Issue 2, Feb 2007, p. 151 - 163
DOI: https://doi.org/10.2174/092986607779816177
- Available online: 01 Feb 2007

Abstract

The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.

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2007-02-01

2025-05-24

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Article Type: Research Article

Keyword(s): Artificial ribonucleases; oligonucleotide conjugates; RNases mimics

Design and Synthesis of Metal-Free Artificial Ribonucleases

Abstract

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