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2000
Volume 13, Issue 7
  • ISSN: 0929-8665
  • E-ISSN: 1875-5305

Abstract

Neuronal tau, through its proline-rich domain and the microtubule binding domain, binds to RNA nonsequence- specifically via electrostatic interaction. This binding inhibits the activity of tau. Tau and RNA were also found to co-localize in SH-SY5Y cells suggesting that RNA has opportunities to interact with tau in cells.

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/content/journals/ppl/10.2174/092986606777790566
2006-07-01
2025-06-11
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