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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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A Structural-Energetic Basis for B-Cell Epitope Prediction
- Source: Protein and Peptide Letters, Volume 13, Issue 7, Jul 2006, p. 743 - 751
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- 01 Jul 2006
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Abstract
Structural-energetic analysis of peptide and protein antigens in the context of binding to antibody reveals fundamental differences between the cross-reactions of antipeptide antibody with protein and antiprotein antibody with peptide, providing a physicochemical basis for B-cell epitope prediction as applied to the development of peptide-based vaccines and immunodiagnostics.
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