Synthesis of Peptidyl Ureas Employing O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)methylcarbamate Derivatives as Activated Monomers

Vommina V. Sureshbabu; Naremaddepalli S. Sudarshan; Gundala C. Krishna

doi:10.2174/092986606776819556

ISSN: 0929-8665
E-ISSN: 1875-5305

Synthesis of Peptidyl Ureas Employing O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)methylcarbamate Derivatives as Activated Monomers
Authors: Vommina V. Sureshbabu¹, Naremaddepalli S. Sudarshan² and Gundala C. Krishna³
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¹ Department of Studies in Chemistry, Central College Campus, Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore 560 001, India. ² Department of Studies in Chemistry, Central College Campus, Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore 560 001, India. ³ Department of Studies in Chemistry, Central College Campus, Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore 560 001, India.
Source: Protein and Peptide Letters, Volume 13, Issue 5, May 2006, p. 493 - 498
DOI: https://doi.org/10.2174/092986606776819556
- Available online: 01 May 2006

Abstract

A convenient and efficient method for the synthesis of dipeptidyl ureas and urea acids employing Osuccinimidyl-( 9H-fluoren-9-ylmethoxycarbonyl amino)methylcarbamates has been described. All the compounds, obtained in good yields, have been fully characterized by mass and NMR spectra.

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2006-05-01

2025-05-28

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Article Type: Research Article

Keyword(s): dichloromethane (DCM); Dipeptidyl Urea Acids; NMR; protease; Schotten-Baumann conditions

Synthesis of Peptidyl Ureas Employing O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)methylcarbamate Derivatives as Activated Monomers

Abstract

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