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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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The Intracellular Distribution and Secretion of Endopeptidases 24.15 415 (Ec 3.4.24.15) and 24.16 (Ec 3.4.24.16)
- Authors: Emer S. Ferro1, Flavia R. Carreno2, Camila Goni3, Paula A.G. Garrido4, Alessander O. Guimaraes5, Leandro M. Castro6, Vitor Oliveira7, Mauricio C. Araujo8, Vanessa Rioli9, Marcelo D. Gomes10, Jose D. Fontenele-Neto11 and Stephen Hyslop12
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View Affiliations Hide Affiliations1 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 2 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 3 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 4 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 5 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 6 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 7 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 8 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 9 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 10 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 11 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil. 12 Departments of Cell Biology and Development, Av. Prof. Lineu Prestes 1524, Room 431, Sao Paulo, 05504- 900, and Biochemistry and Immunology, Ribeirao Preto Faculty of Medicine, Ribeirao Preto, 14049-900, University of Sao Paulo; Laboratory of Neurosciences, City University of Sao Paulo, Sao Paulo, 03071- 000; and Department of Pharmacology, State University of Campinas, 13083-970, Campinas SP, Brazil.
- Source: Protein and Peptide Letters, Volume 11, Issue 5, Oct 2004, p. 415 - 421
- DOI: https://doi.org/10.2174/0929866043406706
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- Available online: 01 Oct 2004
Abstract
Endopeptidase 24.15 (EC 3.4.24.15; EP24.15) and endopeptidase 24.16 (EC 3.4.24.16; EP24.16) are enzymes involved in general peptide metabolism in mammalian cells and tissues. This review will focus on morphological and biochemical aspects related to the subcellular distribution and secretion of these homologous enzymes in the central nervous system. These are important issues for a better understanding of the functions of EP24.15 and EP24.16 within neuroendocrine systems.
© Bentham Science Publishers
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2004-10-01
2025-06-17
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Article Type: Review Article
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