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- Volume 6, Issue 1, 2016
Natural Products Journal, The - Volume 6, Issue 1, 2016
Volume 6, Issue 1, 2016
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The Chemistry and Pharmacology of Genistein
Authors: Atiya Fatima and Ram SinghGenistein is a natural compound belonging to the chemical class of isoflavone. This molecule is present in the significant portion of our diet in the form of Soy food products. This is the most extensively studied isoflavone due to its significance affinity towards targets of potential pharmacological and neutraceutical benefits. The potential pharmacological applications of this molecule have been found as anti-canc Read More
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Nigella sativa – A Functional Spice From A Pharaoh’s Tomb to Modern Healthcare
Authors: Anna Mrozek-Wilczkiewicz and Robert MusiolBlack cumin, Nigella sativa (NS), which is also known as black seed (Kalijeera), is an annual flowering plant from the Ranunculaceae family. Its seeds were used in most ancient medical systems. For ages it was considered to be a panacea. It is rooted in our traditions and has flourished into an intensively investigated medicinal plant. There is an abundance of reports on the biological activities of Nigella sativa seeds or extracts. Read More
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Adequacy of Quality Assurance Programs for a Corn Meal Production Unit
To ensure the quality, the processing of artisanal corn meal in a production unit located in the southeastern state of São Paulo was evaluated. It handles an average of 15 tons/months, all under GMP and HACCP regulations. Of the 153 items examined on a checklist, only 42 were in compliance. In addition, the following Control Points (CPs) were identified: humidification of hominy and corn. The Critical Control Points ( Read More
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Pharmacological Evaluation of Jambrushila Tablet on Animal Model of Type-2 Diabetes
Authors: Bhavesh C. Variya, Anita K Bakrania, Prabodh V. Shah and Snehal S. PatelThe study was undertaken to obtain the scientific evidence to the efficacious claim of the use of Jambrushila Tablet in the management of type-2 diabetes. The SD rats were divided into 4 groups: normal control, disease control, diseased treated with metformin (10 mg/kg) and diseased treated with Jambrushila Tablet (100 mg/kg). Type 2 diabetes was induced in male Sprague Dawley rats by feeding them a high-fat diet i Read More
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Crocin Rich Extract of Nyctanthes arbor-tristis Flower Calyx Induces Anti-angiogenic Activity
Authors: Neha D.Pawar, Shital S.Panchal, Kumaravelu J., Tasneem Shahmalak and Chhaya GadgoliCrocin is an apocarotenoid present in Nyctanthes arbortrisits (NAT) flower calyx extract in abundant quantity of about 36.7% w/w. The carotenoid rich extract of NAT exhibited dose dependant anti-angiogenic effect in chick-chorioallantoic membrane (CAM) assay. The anti-angiogenic activity of NAT extract (1 mg/ml) was observed to be equivalent to Heparin (1 mg/ml) with the IC50 value of 0.5 mg/ml. The antiangiogenic activity Read More
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Effects of Eleutherococcus senticosus Cortex on Recovery from the Forced Swimming Test and Fatty Acid β-Oxidation in the Liver and Skeletal Muscle of mice
Authors: Maho Sumiyoshi and Yoshiyuki KimuraObjective: The root and stem barks of Eleutherococcus senticosus have been used to treat emotional and physical fatigue in China, Russia, Korea, and Japan. The effects of E. senticosus on recovery from physical fatigue and the expenditure of energy currently remain unclear. We herein examined the effects of E. senticosus extract on recovery from physical fatigue after the forced swimming test as well as fatty acid β-ox Read More
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Anti-Inflammatory and Analgesic Activity of Methanolic and Hydro- Alcoholic Extract of Myrsine africana L. Fruits
Authors: Vasudha Abbhi, Lincy Joseph, Ashish K. Jena and Mathew GeorgeMyrsine africana L. (Family Myrsinaceae) commonly known as mirting, is an evergreen shrub found wildly in tropical Asia to Africa. The plant has been traditionally used to treat various diseases and extensively used in folk medicine. The reported literature reveals that there is no pharmacological activities carried out on the fruits of M. africana in order to validate its traditional claim. The aim of the present study is Read More
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Natural Macromolecules in the Development of Safe and Effective Gastroretentive Floating Microparticles of Metformin Hydrochloride
Authors: Mukesh Pandey, Madhuri Maher, Mona Semalty and Ajay SemaltyBackground: Metformin hydrochloride, an oral hypoglycaemic, shows better absorption from upper part of the gastric region. Natural/herbal substances have been investigated for the development of natural polymer-based drug delivery systems owing to the desirable properties like biodegradability, biocompatibility, aqueous solubility, swelling ability, easy availability and cost effectiveness. Method: Therefore, three n Read More
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Phytochemical Screening and Antibacterial Activity of Aloe Vera Collected from Different Climatic Regions of India
Authors: Sandeep Kumar, Lalita Budhwar, Amita Yadav, Manila Yadav and Jaya Parkash YadavBackground: Metformin hydrochloride, an oral hypoglycaemic, shows better absorption from upper part of the gastric region. Natural/herbal substances have been investigated for the development of natural polymer-based drug delivery systems owing to the desirable properties like biodegradability, biocompatibility, aqueous solubility, swelling ability, easy availability and costeffectiveness. Method: Therefore, three na Read More
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