Natural Products Journal, The - Volume 2, Issue 4, 2012

The effect of extraction solvents (methanol, 95%ethanol, and water) on total phenolic contents and free radical scavenging activity (FRSA) of Gynura procumbens leaf was investigated. The contents of total phenolic and in vitro FRSA were significantly higher in the methanol extract compared to the 95% ethanol and water extracts. Consequently, the effect of the methanol extract on plasma lipid peroxidation and pla Read More

Phytochemical investigation of the methanolic extract of Aegle marmelos (L.) Corr. (Rutaceae) roots resulted in the isolation of two new diterpenic coumarin ethers characterized as 8-(2´,6´,10´,14´-tetramethylhexadec-5´,13´-dien-3´-oxo) coumarin (2) and 8-(2´,6´,10´,14´-tetramethylhexadec-13´-en-3´-oxo) coumarin (3) and two new sesquiterpenic coumarin ethers identified as 8-(4´β,10´α-dimethyl-7´-iso Read More

A new phenyl alcohol and two new phenolic glycosides isolated from the methanolic extract of the stem bark of Morus alba L. (Moraceae) have been characterized as n-triacontan-7-ol-13-oxo-yl 3,4-dioxymethylene benzene (1), noctadecanyl- β-D-arabinofuranosyl-(1→2)-β-D-arabinofuranosyl-(1→2)-β-D-arabinofuranosyl-3” ” -methoxy-4” ” -hydroxy cinnamate (stearyltriarabinoferulate) (2) and 3-methoxy-4,5-d Read More

Objective: Alpinia calcarata Roscoe (F. Zingiberaceae) rhizomes are often used in Sri Lankan traditional systems of medicine as a remedy for bronchitis, cough, respiratory ailments, diabetics, asthma and arthritis. Present review summarizes chemical, pharmacognostical, pharmacological and toxicological investigations carried out on A. calcarata of Sri Lankan origin. Methods: Composition of A. calcarata essential oil was a Read More

Complementary and alternative medicine (CAM) has use in certain parts of the world and has gained increasing interest. People with epilepsy (PWE) take natural products or other forms of CAM mainly to enhance general health, but also to prevent seizures or to alleviate symptoms of co-morbidities or side effects of antiepileptic medications. The well developed medical systems, such as traditional Chinese Medicine (TCM), Read More

The present work was designed to compare the in vitro antioxidant, antibacterial and cytotoxic properties of microwave assisted (MWSV) and Soxhlet assisted extracts of Solanum viarum fruits (SESV). The total phenol and flavonol contents of both the extracts were determined. The extracts were evaluated for in vitro antioxidant activity in different models and antibacterial activity against different bacterias and also Read More

Investigation on the secondary metabolites of the leaves of Phlogacanthus pubinervius Nees. led to the isolation of a new terpenoidal glycoside, 3-O-[ß-D-glucopyranosyl-(1’→2’)-α-L-rhamnopyranosylphlogaca-nthoside], 5 along with five other compounds including β-sitosterol (1), β-sitosterol-D-glucoside (2), Stigmasta-5,22-dien-7-on-3ß-ol (3), 19-hydroxy- phlogacantholide (4), and (2E,7Z)-2,6-dihydroxycycloocta-2,7-dienone (6). Read More

The contents of cell wall polysaccharides in pericarp tissues of immature Hayward kiwifruit were determined during development. Two methods employed to remove starch from the crude cell wall preparations were enzymatic digestion (porcine pancreatic α-amylase and Pseudomonas iso-amylase, Method 1) and dimethyl sulfoxide extraction (DMSO, Method 2). Method 2 was more effective in removing starch than Method Read More

An in vitro method to improve the production of vincristine (VCR) was developed by using CaCl2 elicitor in embryogenic suspension culture of C. roseus. CaCl2 at various levels [0 mM (T0), 5 mM (T1), 25 mM (T2), 50 mM (T3), 75 mM (T4) and 100 mM (T5)] was added in MS medium as an elicitor molecule. Cultural growth in terms of absolute dry mass, packed cell volume, colony area was increased up to T2 treatment and Read More

Objective: To investigate nephroprotective potential of Urtica parviflora (UP) against paracetamol (PCM) induced nephrotoxicity in rats. Methods: Nephrotoxicity was induced in rats by chronic administration of PCM (1 g/kg body weight p.o.) for 21 days. Different doses of UP (250, 500 and 750 mg/kg b.w., p.o.) were administered for 21 days along with PCM. Blood urea, blood urea nitrogen (BUN), serum creatinine, total protein, Read More

Context: Celtis australis L. (Ulmaceae) is a deciduous tree distributed in mountainous and sub-mountainous Himalaya. This plant has been used as traditional medicine in bone fracture, pimples, contusions, sprains and joint pains in India. Objectives: This is the first evaluation of C. australis extracts (bark and fruits) and fatty acids (fruits) for acute toxicity, analgesic, and anti-inflammatory activities. Materials and methods: Th Read More

Although there are many chemicals used for sterilization purposes such as ethanol, hydrogen peroxide, bromine water, mercuric chloride, silver nitrate and antibiotics, sodium hypochlorite solutions have been most widely used. Since NaOCl has a strong oxidizing property which makes it highly reactive with amino acids, nucleic acids, amines, and amides, it is highly effective against all kinds of bacteria, fungi, and viruses. Read More