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Volume 4, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882
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Abstract

Background

Smoking in any form is a significant risk factor for developing cardiovascular diseases, chronic obstructive pulmonary disease, lung cancer, and other oxidative damage-induced diseases. The increasing global trend of E-cigarettes has led traditional smokers to perceive them as a safer option.

Objectives

This study aimed to compare the levels of malondialdehyde (MDA) as a marker of oxidative damage and high-sensitivity C-reactive protein (hs-CRP) as a marker of inflammation between pure E-cigarette users and tobacco poly-users (smoking combinations of traditional products). Moreover, it also evaluated the influence of Body Mass Index, frequency, and duration of vaping/smoking on these biomarkers.

Materials and Methods

This analytical cross-sectional pilot study included 40 males aged 18-25 (20 pure E-cigarette users and 20 tobacco poly-users). MDA and hs-CRP were estimated on serum, and SPSS-Version 28.0.1.1 was used for data analysis. Mean hs-CRP and MDA levels for the two groups were compared using the Mann-Whitney-U test.

Results

Mean level of hs-CRP between the two groups was not significantly different. However, MDA levels were lower in pure E-cigarette users than in tobacco poly-users, especially among those with normal BMI and those who vaped/smoked more frequently and for a longer duration.

Conclusion

Oxidative damage was lesser for pure E-cigarette users and could potentially be the less harmful option than tobacco poly-use. However, E-cigarettes are not the safest substitute for conventional smoking as it causes a similar extent of risk for inflammation-related CVD. Findings need further exploration to study the long-term effects on a larger population group to draw definitive conclusions.

© 2023 Bentham Science Publishers
© 2023 The Author(s). Published by Bentham Science Publisher. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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/content/journals/nemj/10.2174/04666230302120808
2023-05-10
2025-01-19

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/content/journals/nemj/10.2174/04666230302120808
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Electronic Cigarettes Versus Tobacco Poly Use: Reduced Oxidative Stress but Similar Inflammatory Effect
NEW Emirates Medical J 4, e020323214265 (2023); https://doi.org/10.2174/04666230302120808
/content/journals/nemj/10.2174/04666230302120808
/content/journals/nemj/10.2174/04666230302120808
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  • Article Type:     Research Article
Keyword(s): E-cigarettes; High sensitivity C-reactive protein (hs-CRP); Inflammation; Malondialdehyde (MDA); Oxidative damage; Tobacco polyuse; Vaping

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