Skip to content
2000
Volume 4, Issue 2
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882

Abstract

Background

The topic of COVID-19 (coronavirus disease)-associated complications during pregnancy is poorly postulated and remains an area that requires elucidation for the underlying pathophysiology mechanism in order to evaluate a new therapeutic strategy and optimize current therapies.

Aims

The study aimed to assess the proportion of associated complications with COVID-19 and the underlying pathophysiology in pregnant women.

Methods

The MedLine and Embase databases were searched for studies relevant to the study topic.

Results

Preterm delivery and C-section have been found to be the most frequently reported complications. Approximately, 28.55% of pregnant women with symptomatic COVID-19 have been reported to require a C-section and 8.8% preterm delivery. In addition, anxiety and depression have also been frequently reported in 57% and 37% of pregnant women, respectively.

Conclusion

Symptomatic pregnant women with COVID-19 have a high risk of preterm labor, mortality and morbidity rates, and C-section requirements. The underlying pathophysiology of COVID-19-associated complications during pregnancy includes homeostatic disturbances of the immune system, pulmonary system, and hemostatic system. In addition to endothelial dysfunction, excessive immune response, coagulopathy, hypoxemia, and hypotension are involved in the pathogenesis that negatively affects neonates' health outcomes.

© 2023 The Author(s). Published by Bentham Science Publisher. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
Loading

Article metrics loading...

/content/journals/nemj/10.2174/0250688204666230519145707
2023-07-18
2025-07-05
The full text of this item is not currently available.

References

  1. HarelL. EliasiE. LifshitzS. J. SchindlerY. RosenD. OlteanuI. RottenstreichA. TzabariA. Does the presence of symptoms affect pregnancy outcomes in third trimester in women with SARS-CoV-2.J. Matern. -Fetal Neonatal Med.20217582758910.1080/14767058.2021.1956895
    [Google Scholar]
  2. TrombettaA. ComarM. TommasiniA. CantonM. CampiscianoG. ZanottaN. CasonC. MasoG. RissoF.M. SARS-CoV-2 infection and inflammatory response in a twin pregnancy.Int. J. Environ. Res. Public Health2021186307510.3390/ijerph1806307533802696
    [Google Scholar]
  3. KumarV. PrasathA. BlancoC. KenneyP. OstwaldC. MeyerT. ClementiC. MaciejewskiR. WilbyM. ReynoldsA. HpaN. YuK. Respiratory failure in an extremely premature neonate with COVID-19.Children20218647710.3390/children806047734200043
    [Google Scholar]
  4. Dávila-AliagaC. Espínola-SánchezM. Mendoza-IbáñezE. Guevara-RíosE. Torres-MarcosE. Hinojosa-PérezR. Espinoza-VivasY. Álvarez-CarrascoR. Velásquez-VásquezC. Meza-SantibáñezL. Gonzales-CarrilloO. Arango-OchanteP. Racchumí-VelaA. Saldaña-DíazC. Perinatal outcomes and serological results in neonates of pregnant women seropositive to SARS-CoV-2: A cross-sectional descriptive study.Medwave20202011e8084e808410.5867/medwave.2020.11.808433382393
    [Google Scholar]
  5. MullinsE. HudakM.L. BanerjeeJ. GetzlaffT. TownsonJ. BarnetteK. PlayleR. PerryA. BourneT. LeesC.C. NallapetaS. MillsE. PeersB. StablesS. IliodromitiS. ArmstrongM. OwenH. MccootyS. AsgharA. MutemaE. TantonE. SysonJ. ThorntonD. GoddardJ. GoddardJ. RomeroE. BrayM. BourkeM. TrepteL. CresswellJ. BallingT. AtkinsonV. AjayB. MargaritL. ToureS. WindsorL. WixtedD. Zill-E-HumaR. VasuV. WoodwardZ. HammondB. HassanW. GadaR. MasonN. MidwifC. EmmetL. ChapmanL. CoxonS. Moller-ChristensenC. JaleelS. HarringtonS.C. DaviesR. KnightC. RevellK. NejadA. AminA. AladangadyN. SherrisL. MullinsE. MansfieldR. RavenJ-L. MartinH. WyattC. RobinsonK. JavaidM. SukruthaV. MahdiA. FayadhA. SwaminathanL. RatcliffeS. GbinigieH. KausarS. HarringtonA. SouthamD. LearE. KousarR. MeadJ. BlackM. CrawfordI. VinerA. NicollA. HarrisL. BaleN. RatherB. EssienS. GowansS. HusonC. HusonC. BarkerK. CantliffeJ. MossopJ. NewportR. Susara BlundenR.M. GarnerZ. HigginsS. LeeF. WatkinsK. TipperJ. AndersonM. EverdenC. BressingtonC. RandA. ShahN. JokhiR. RajeswaryJ. MillwardH. MackayA. KhundaA. Co-PI is Kim HinshawA.A. O’BrienC. McKeownG. BishopL. RobinsonS. GreerS. HealC. GortiM. JonesS. Anim-SomuahM. JarvieW.E. CamarasaL. MurthaV. WeeL. KidwaiS. ChurchillD. ClohertyK. FloodC. EkladiosS. KermackA. MalarselviM. GiriV. LieblingR. SatodiaP. RadfordJ. ChesterM. KhareM. WuP. HalawaS. PerkinsD. AryaR. NarayananS. SinhaB. MeadowsE. GrindeyJ. BrainJ. VermaA. CollinsE. ShahA. PandeyB. HughesR. DooksE. JamesT. TarftH. DanielsA. ParrottM. NewmanT. ThomasA. DaviesS. HollinsM. WoodheadA. TakacsF. StoddardE. RheadK. EedleJ. FranklandL. HomeM. HolroydK. Sutton-ColeA. KeepingV. SinghN. WestA. Kelly-BaxterM. Barker-WilliamsK. JenningsJ. UpsonG. PikeJ. CreethA. GriceA. SellersH. JohnsonS. RandJ. HazeltonT. HooleL. TaylorS. ParlapalliS. ClarkeG. Gross-GibbsK. EdwardsA. SmithC. GrantR. TrusloveT. LewinA. AriasA.M. DunhamT. WillisL. MathewA. Bowdler-HayesM. PerryA. GoodierJ. JenkinsE. KeableJ. GoodwinG. ClarkK. MaternityK. EarnshawJ. WagstffJ. SaadC. HoltS. HadlowP. HyslopM. AmblerS-J. VirdeeS. MphansiE. PepperS. DixonC. CastleG. ClareE. PauloseM. CampbellC. CokeL. AlvarezM. HardyR. GovindA. RamshawA. CarpenterJ. MorriesK. Ashbrook-RabyC. AndersonH. HodgenL. BuckL. NewportR. GrigsbyS. Glyn-JonesL. ChapmanL. DorningA. BlakeC. PyartE. BlackG. BurnardS. MorganH. HenryL. GillM. KennyT. O’BrienK. HarwoodH. ParishG. JukesK. ThompsonF. HaslamZ. HakeD. BennettS. MaherS. WatkinsE. RudingE. VigniD. LalK. YelnoorkarF. RichesJ. StainesN. CotonZ. DevisonL. MarshallC. NethertonK. LeverE. WellsteadS. O’LearyL. WattsR. HanningtonR.L.A. BrewerF. PrinceC. MillerS. PattersonM. O’RourkeA. HollandsH. CopeV. RoughleyL. DurneaU. MaudlinL. RiddlesL. CannonsV. TownsendK. WilliamsC. EvansM. WoodD. ElliottK. InghamJ. Pregnancy and neonatal outcomes of COVID-19: Coreporting of common outcomes from PAN-COVID and AAP-SONPM registries.Ultrasound Obstet. Gynecol.202157457358110.1002/uog.2361933620113
    [Google Scholar]
  6. YangR. MeiH. ZhengT. FuQ. ZhangY. BukaS. YaoX. TangZ. ZhangX. QiuL. ZhangY. ZhouJ. CaoJ. WangY. ZhouA. Pregnant women with COVID-19 and risk of adverse birth outcomes and maternal-fetal vertical transmission: A population-based cohort study in Wuhan, China.BMC Med.202018133010.1186/s12916‑020‑01798‑133070775
    [Google Scholar]
  7. EgerupP. Fich OlsenL. ChristiansenA.M.H. WestergaardD. SeverinsenE.R. HviidK.V.R. KolteA.M. BojeA.D. BertelsenM.L.M.F. PrætoriusL. ZedelerA. NielsenJ.R. BangD. BerntsenS. Ethelberg-FindsenJ. StormD.M. Bello-RodríguezJ. InghamA. Ollé-LópezJ. HoffmannE.R. Wilken-JensenC. KrebsL. JørgensenF.S. WesthH. JørgensenH.L. la Cour FreieslebenN. NielsenH.S. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies at Delivery in Women, Partners, and Newborns.Obstet. Gynecol.20211371495510.1097/AOG.000000000000419933116054
    [Google Scholar]
  8. WeiS.Q. Bilodeau-BertrandM. LiuS. AugerN. The impact of COVID-19 on pregnancy outcomes: A systematic review and meta-analysis.CMAJ202119316E540E54810.1503/cmaj.20260433741725
    [Google Scholar]
  9. Martinez-PerezO. Prats RodriguezP. Muner HernandezM. Encinas PardillaM.B. Perez PerezN. Vila HernandezM.R. Villalba YarzaA. Nieto VelascoO. Del Barrio FernandezP.G. Forcen AcebalL. Orizales LagoC.M. Martinez VareaA. Muñoz AbellanaB. Suarez AranaM. Fuentes RicoyL. Martinez DiagoC. Janeiro FreireM.J. Alférez Alvarez-MalloM. Casanova PedrazC. Alomar MateuO. Lesmes HerediaC. Wizner de AlvaJ.C. Bernardo VegaR. Macia BadiaM. Alvarez ColomoC. Sanchez MuñozA. Pratcorona AlicartL. Alonso SaizR. Lopez RodriguezM. CarmenD.B.L.M. MecaC.M.R. VaquerizoR.O. MoranA.E. NuñezV.M.J. FernandezF.C. TubauN.A. Cano GarciaA.M. Baena LuqueC. Soldevilla PerezS. Gastaca AbasoloI. Adanez GarciaJ. Teulon GonzalezM. PuertasP.A. OstosS.R. del PilarG.M.M. CatalinaC.M. FerriolsP.E. CañoA.A. De la Cruz ContyM.L. SainzB.J.A. The association between SARS-CoV-2 infection and preterm delivery: A prospective study with a multivariable analysis.BMC Pregnancy Childbirth202121127310.1186/s12884‑021‑03742‑433794829
    [Google Scholar]
  10. PapageorghiouA.T. DeruelleP. GunierR.B. RauchS. García-MayP.K. MhatreM. UsmanM.A. Abd-ElsalamS. EtukS. SimmonsL.E. NapolitanoR. DeantoniS. LiuB. PrefumoF. SavasiV. do ValeM.S. BaafiE. ZainabG. NietoR. MaizN. AminuM.B. Cardona-PerezJ.A. CraikR. WinseyA. TavchioskaG. BakoB. OrosD. RegoA. BenskiA.C. Hassan-HangaF. SavoraniM. GiulianiF. SentilhesL. RissoM. TakahashiK. VecchiarelliC. IkenoueS. ThiruvengadamR. Soto ContiC.P. FerrazziE. CetinI. NachinabV.B. ErnawatiE. DuroE.A. KholinA. FirlitM.L. EasterS.R. SichitiuJ. BowaleA. CasaleR. CerboR.M. CavorettoP.I. EskenaziB. ThorntonJ.G. BhuttaZ.A. KennedyS.H. VillarJ. Preeclampsia and COVID-19: Results from the INTERCOVID prospective longitudinal study.Am. J. Obstet. Gynecol.20212253289.e1289.e1710.1016/j.ajog.2021.05.01434187688
    [Google Scholar]
  11. HarahapA. HariantoA. EtikaR. UtomoM.T. AngelikaD. HandayaniK.D. Arif SampurnaM.T. Spontaneous Ileum Perforation in a premature twin with Coronavirus-19 positive mother.J. Pediatr. Surg. Case Rep.20216710180710.1016/j.epsc.2021.10180733564621
    [Google Scholar]
  12. LiuC. AndrusierM. SilverM. ApplewhiteL. ClareC.A. Effect of SARS-CoV-2 infection on pregnancy outcomes in an inner-city black patient population.J. Community Health20214651029103510.1007/s10900‑021‑00988‑z33855649
    [Google Scholar]
  13. de Vasconcelos GasparA. Santos SilvaI. SARS-CoV-2 in Pregnancy—The First Wave.Medicina (Kaunas)202157324110.3390/medicina57030241
    [Google Scholar]
  14. KoJ.Y. DeSistoC.L. SimeoneR.M. EllingtonS. GalangR.R. OduyeboT. GilboaS.M. LaveryA.M. GundlapalliA.V. Shapiro-MendozaC.K. Adverse pregnancy outcomes, maternal complications, and severe illness among US delivery hospitalizations with and without a coronavirus disease 2019 (COVID-19) diagnosis.Clin. Infect. Dis.202173Suppl. 1S24S3110.1093/cid/ciab34433977298
    [Google Scholar]
  15. SinghV. ChoudharyA. DattaM.R. RayA. Maternal and neonatal outcomes of COVID-19 in pregnancy: A single-centre observational study.Cureus2021132e1318410.7759/cureus.1318433717728
    [Google Scholar]
  16. Gurol-UrganciI. JardineJ.E. CarrollF. DraycottT. DunnG. FremeauxA. HarrisT. HawdonJ. MorrisE. MullerP. WaiteL. WebsterK. van der MeulenJ. KhalilA. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: National cohort study.Am. J. Obstet. Gynecol.20212255522.e1522.e1110.1016/j.ajog.2021.05.01634023315
    [Google Scholar]
  17. PirjaniR. HosseiniR. SooriT. RabieiM. HosseiniL. AbiriA. MoiniA. ShizarpourA. RazaniG. SepidarkishM. Maternal and neonatal outcomes in COVID-19 infected pregnancies: A prospective cohort study.J. Travel Med.2020277taaa15810.1093/jtm/taaa15832889551
    [Google Scholar]
  18. MeloG.C. AraújoK.C.G.M. COVID-19 infection in pregnant women, preterm delivery, birth weight, and vertical transmission: A systematic review and meta-analysis.Cad. Saude Publica2020367e0008732010.1590/0102‑311x00087320
    [Google Scholar]
  19. TrahanM.J. MalhaméI. O’FarrellP. MitricC. DesiletsJ. BastrashM.P. El-MessidiA. AbenhaimH.A. Obstetrical and Newborn Outcomes Among Patients With SARS-CoV-2 During Pregnancy.J. Obstet. Gynaecol. Can.2021437888892.e110.1016/j.jogc.2021.03.01233785466
    [Google Scholar]
  20. BiasucciG. CannalireG. RaymondA. CapraM.E. BenenatiB. VadaccaG. SchiavoR. PavesiC. BoniniR. Safe Perinatal Management of Neonates Born to SARS-CoV-2 Positive Mothers at the Epicenter of the Italian Epidemic.Front Pediatr.2020856552210.3389/fped.2020.56552233194893
    [Google Scholar]
  21. SteffenH.A. SwartzS.R. JacksonJ.B. KenneK.A. Ten EyckP.P. MerrymanA.S. CastanedaC.N. MarsdenK. MaxwellT. MerrillA.E. KrasowskiM.D. RysavyM.B. SARS-CoV-2 infection during pregnancy in a rural midwest all-delivery cohort and associated maternal and neonatal outcomes.Am. J. Perinatol.202138661462110.1055/s‑0041‑172393833611783
    [Google Scholar]
  22. VillarJ. AriffS. GunierR.B. ThiruvengadamR. RauchS. KholinA. RoggeroP. PrefumoF. do ValeM.S. Cardona-PerezJ.A. MaizN. CetinI. SavasiV. DeruelleP. EasterS.R. SichitiuJ. Soto ContiC.P. ErnawatiE. MhatreM. TejiJ.S. LiuB. CapelliC. ObertoM. SalazarL. GravettM.G. CavorettoP.I. NachinabV.B. GaladanciH. OrosD. AyedeA.I. SentilhesL. BakoB. SavoraniM. CenaH. García-MayP.K. EtukS. CasaleR. Abd-ElsalamS. IkenoueS. AminuM.B. VecciarelliC. DuroE.A. UsmanM.A. John-AkinolaY. NietoR. FerrazziE. BhuttaZ.A. LangerA. KennedyS.H. PapageorghiouA.T. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection.JAMA Pediatr.2021175881782610.1001/jamapediatrics.2021.105033885740
    [Google Scholar]
  23. CanigliaE.C. MagosiL.E. ZashR. DisekoM. MayondiG. MabutaJ. PowisK. Dryden-PetersonS. MosepeleM. LuckettR. MakhemaJ. MmalaneM. LockmanS. ShapiroR. Modest reduction in adverse birth outcomes following the COVID-19 lockdown.Am. J. Obstet. Gynecol.20212246615.e1615.e1210.1016/j.ajog.2020.12.119833347842
    [Google Scholar]
  24. HigginsJ.P.T. AltmanD.G. GøtzscheP.C. JüniP. MoherD. OxmanA.D. SavovićJ. SchulzK.F. WeeksL. SterneJ.A.C. Cochrane Bias Methods Group Cochrane Statistical Methods Group The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials.BMJ2011343oct18 2d592810.1136/bmj.d592822008217
    [Google Scholar]
  25. JordanZ. LockwoodC. MunnZ. AromatarisE. The updated joanna briggs institute model of evidence-based healthcare.Int. J. Evid.-Based Healthc.2019171587110.1097/XEB.000000000000015530256247
    [Google Scholar]
  26. Di MascioD. KhalilA. SacconeG. RizzoG. BucaD. LiberatiM. VecchietJ. NappiL. ScambiaG. BerghellaV. D’AntonioF. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: A systematic review and meta-analysis.Am. J. Obstet. Gynecol. MFM20202210010710.1016/j.ajogmf.2020.10010732292902
    [Google Scholar]
  27. LokkenE.M. WalkerC.L. DelaneyS. KachikisA. KretzerN.M. EricksonA. ResnickR. VanderhoevenJ. HwangJ.K. BarnhartN. RahJ. McCartneyS.A. MaK.K. HuebnerE.M. ThomasC. ShengJ.S. PaekB.W. RetzlaffK. KlineC.R. MunsonJ. BlainM. LaCourseS.M. DeutschG. Adams WaldorfK.M. Clinical characteristics of 46 pregnant women with a severe acute respiratory syndrome coronavirus 2 infection in Washington State.Am. J. Obstet. Gynecol.20202236911.e1911.e1410.1016/j.ajog.2020.05.03132439389
    [Google Scholar]
  28. SavasiV.M. ParisiF. PatanèL. FerrazziE. FrigerioL. PellegrinoA. SpinilloA. TateoS. OttoboniM. VeroneseP. PetragliaF. VerganiP. FacchinettiF. SpazziniD. CetinI. Clinical findings and disease severity in hospitalized pregnant women with coronavirus disease 2019 (COVID-19).Obstet. Gynecol.2020136225225810.1097/AOG.000000000000397932433453
    [Google Scholar]
  29. SentilhesL. De MarcillacF. JouffrieauC. KuhnP. ThuetV. HansmannY. RuchY. Fafi-KremerS. DeruelleP. Coronavirus disease 2019 in pregnancy was associated with maternal morbidity and preterm birth.Am. J. Obstet. Gynecol.20202236914.e1914.e1510.1016/j.ajog.2020.06.02232553908
    [Google Scholar]
  30. LokkenE.M. HuebnerE.M. TaylorG.G. HendricksonS. VanderhoevenJ. KachikisA. ColerB. WalkerC.L. ShengJ.S. al-HaddadB.J.S. McCartneyS.A. KretzerN.M. ResnickR. BarnhartN. SchulteV. BergamB. MaK.K. AlbrightC. LariosV. KelleyL. LariosV. EmhoffS. RahJ. RetzlaffK. ThomasC. PaekB.W. HsuR.J. EricksonA. ChangA. MitchellT. HwangJ.K. EricksonS. DelaneyS. ArchabaldK. KlineC.R. LaCourseS.M. Adams WaldorfK.M. Washington State COVID-19 in Pregnancy Collaborative Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State.Am. J. Obstet. Gynecol.2021225177.e177.e1410.1016/j.ajog.2020.12.122133515516
    [Google Scholar]
  31. WangY. ChenL. WuT. ShiH. LiQ. JiangH. ZhengD. WangX. WeiY. ZhaoY. QiaoJ. Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: A longitudinal cohort study in China.BMC Med.202018134710.1186/s12916‑020‑01825‑133143711
    [Google Scholar]
  32. AntounL. TaweelN.E. AhmedI. PatniS. HonestH. Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study.Eur. J. Obstet. Gynecol. Reprod. Biol.202025255956210.1016/j.ejogrb.2020.07.00832732059
    [Google Scholar]
  33. NormanM. NavérL. SöderlingJ. AhlbergM. Hervius AsklingH. AronssonB. ByströmE. JonssonJ. SengpielV. LudvigssonJ.F. HåkanssonS. StephanssonO. Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes.JAMA2021325202076208610.1001/jama.2021.577533914014
    [Google Scholar]
  34. HarveyE. M. McNeerE. McDonaldM. F. Shapiro-MendozaC. K. DupontW. D. BarfieldW. PatrickS. W. Association of preterm birth rate with COVID-19 Statewide Stay-at-Home Orders in Tennessee.JAMA Pediatrics202163563710.1001/jamapediatrics.2020.6512
    [Google Scholar]
  35. GulersenM. BlitzM.J. RochelsonB. NimaroffM. ShanW. BornsteinE. Clinical Implications of SARS-CoV-2 Infection in the Viable Preterm Period.Am. J. Perinatol.202037111077108310.1055/s‑0040‑171385132615621
    [Google Scholar]
  36. Ortiz MolinaE. Hernandez PailosR. Pola GuillenM. Pascual PedrenoA. Rodriguez RodriguezE. Hernandez MartinezA. COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: A retrospective analysis.Ginekol. Pol.2020911275576310.5603/GP.a2020.013033447995
    [Google Scholar]
  37. PatelP. KulkarniS. GuerreroM. PersaudC. ZuberiJ. RebeinB. Emergency Cesarean Section at 38 Weeks of Gestation with COVID-19 Pneumonia: A Case Report.Am. J. Case Rep.202122e92659110.12659/AJCR.92659133339814
    [Google Scholar]
  38. ChenS. BernsteinP. NairS. RomanelliE. KhouryR. LabinsJ. FioricaG. ReddyS. A review of 92 obstetric patients with COVID-19 in the Bronx, New York and their peripartum anaesthetic management.Anaesthesiol. Intensive Ther.202153211512510.5114/ait.2021.10512034006045
    [Google Scholar]
  39. Martínez-PerezO. VougaM. Cruz MelguizoS. Forcen AcebalL. PanchaudA. Muñoz-ChápuliM. BaudD. Association between mode of delivery among pregnant women with COVID-19 and maternal and neonatal outcomes in Spain.JAMA2020324329629910.1001/jama.2020.1012532511673
    [Google Scholar]
  40. CarrascoI. Muñoz-ChapuliM. Vigil-VázquezS. Aguilera-AlonsoD. HernándezC. Sánchez-SánchezC. OliverC. RiazaM. ParejaM. SanzO. Pérez-SeoaneB. LópezJ. MárquezE. Domínguez-RodríguezS. Hernanz-LoboA. De León-LuisJ.A. Sánchez-LunaM. NavarroM.L. SARS-COV-2 infection in pregnant women and newborns in a Spanish cohort (GESNEO-COVID) during the first wave.BMC Pregnancy Childbirth202121132610.1186/s12884‑021‑03784‑833902483
    [Google Scholar]
  41. CavalcanteM.B. CavalcanteC.T.M.B. SarnoM. BariniR. Kwak-KimJ. Maternal immune responses and obstetrical outcomes of pregnant women with COVID-19 and possible health risks of offspring.J. Reprod. Immunol.202114310325010.1016/j.jri.2020.10325033249335
    [Google Scholar]
  42. MokhtariN.B. DrassinowerD. OrrL.A. CobbN.K. MimsO.L.Jr LandyH.J. Expectant management of severe COVID-19 pneumonia in late preterm pregnancy and subsequent cholecystitis: lessons learned.AJP Rep.2021111e29e3310.1055/s‑0040‑172167233598363
    [Google Scholar]
  43. RosenH. BartY. ZlatkinR. Ben-SiraL. Ben BashatD. AmitS. CohenC. Regev-YochayG. YinonY. Fetal and perinatal outcome following first and second trimester COVID-19 infection: Evidence from a prospective cohort study.J. Clin. Med.20211010215210.3390/jcm1010215234065646
    [Google Scholar]
  44. RottenstreichA. TsurA. BravermanN. KabiriD. PoratS. BenensonS. OsterY. KamH.A. WalfischA. BartY. MeyerR. LifshitzS.J. AmikamU. Biron-ShentalT. CohenG. Sciaky-TamirY. ShacharI.B. YinonY. ReubinoffB. Vaginal delivery in SARS-CoV-2-infected pregnant women in Israel: A multicenter prospective analysis.Arch. Gynecol. Obstet.202130361401140510.1007/s00404‑020‑05854‑233123808
    [Google Scholar]
  45. KolkovaZ. BjurströmM.F. LänsbergJ.K. SvedasE. HamerM.A. HanssonS.R. HerbstA. ZaighamM. Obstetric and intensive-care strategies in a high-risk pregnancy with critical respiratory failure due to COVID-19: A case report.Case Rep. Womens Health202027e0024010.1016/j.crwh.2020.e0024032714844
    [Google Scholar]
  46. BajpaiD. ShahS. COVID-19 pandemic and pregnancy in kidney disease.Adv. Chronic Kidney Dis.202027539740310.1053/j.ackd.2020.08.00533308505
    [Google Scholar]
  47. MetzT.D. CliftonR.G. HughesB.L. SandovalG. SaadeG.R. GrobmanW.A. ManuckT.A. MiodovnikM. SowlesA. ClarkK. Gyamfi-BannermanC. Mendez-FigueroaH. SehdevH.M. RouseD.J. TitaA.T.N. BailitJ. CostantineM.M. SimhanH.N. MaconesG.A. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19).Obstet. Gynecol.2021137457158010.1097/AOG.000000000000433933560778
    [Google Scholar]
  48. LebelC. MacKinnonA. BagshaweM. Tomfohr-MadsenL. GiesbrechtG. Elevated depression and anxiety symptoms among pregnant individuals during the COVID-19 pandemic.J. Affect. Disord.202027751310.1016/j.jad.2020.07.12632777604
    [Google Scholar]
  49. McFarlandM.J. McFarlandC.A.S. HillT.D. D’OriaR. Postpartum depressive symptoms during the beginning of the COVID-19 Pandemic: An examination of population birth data from central New Jersey.Matern. Child Health J.202125335335910.1007/s10995‑020‑03116‑w33492587
    [Google Scholar]
  50. HiiragiK. ObataS. MisumiT. MiyagiE. AokiS. Psychological stress associated with the COVID ‐19 pandemic in postpartum women in Yokohama, Japan.J. Obstet. Gynaecol. Res.20214762126213010.1111/jog.1477633759283
    [Google Scholar]
  51. PreisH. MahaffeyB. PatiS. HeiselmanC. LobelM. Adverse perinatal outcomes predicted by prenatal maternal stress among U.S. women at the COVID-19 pandemic onset.Ann. Behav. Med.202155317919110.1093/abm/kaab00533724334
    [Google Scholar]
  52. SeyedA. KarimiA. ShobeiriP. NowrooziA. MehraeenE. AfsahiA. BarzegaryA. Psychological symptoms of COVID-19 epidemic: A systematic review of current evidence.Psihologija202154217319210.2298/PSI200703035S
    [Google Scholar]
  53. WangM.J. SchaperoM. IversonR. YarringtonC.D. Obstetric hemorrhage risk associated with novel COVID-19 diagnosis from a single-institution cohort in the United States.Am. J. Perinatol.202037141411141610.1055/s‑0040‑171840332992351
    [Google Scholar]
  54. Cruz MelguizoS. de la Cruz ContyM. Carmona PayánP. Abascal-SaizA. Pintando RecarteP. González RodríguezL. Cuenca MarínC. Martínez VareaA. Oreja CuestaA. RodríguezP. Fernández BuhigasI. Rodríguez GallegoM. Fernández AlonsoA. López PérezR. Broullón MolanesJ. Encinas PardillaM. Ramírez GómezM. Gimeno GimenoM. Sánchez MuñozA. Martínez-PérezO. Pregnancy outcomes and SARS-CoV-2 infection: The Spanish obstetric emergency group study.Viruses202113585310.3390/v1305085334067086
    [Google Scholar]
  55. BloiseE. ZhangJ. NakpuJ. HamadaH. DunkC.E. LiS. ImperioG.E. NadeemL. KibschullM. LyeP. MatthewsS.G. LyeS.J. Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia.Am. J. Obstet. Gynecol.20212243298.e1298.e810.1016/j.ajog.2020.08.05532853537
    [Google Scholar]
  56. MarzoogB.A. VlasovaT.I. The possible puzzles of BCG vaccine in protection against COVID-19 infection.Egypt. J. Bronchol.2021151710.1186/s43168‑021‑00052‑3
    [Google Scholar]
  57. ZhouC. G. PackerC. H. HershA. R. CaugheyA. B. Antenatal corticosteroids for pregnant women with COVID-19 infection and preterm prelabor rupture of membranes: A decision analysis.J. Matern. Neonatal Med.20203591643165110.1080/14767058.2020.1763951
    [Google Scholar]
  58. Abdullah MarzoogB. Adaptive and Compensatory Mechanisms of the Cardiovascular System and Disease Risk Factors in young males and females.Emir. Med. J.2022410.2174/04666221128110145
    [Google Scholar]
  59. MarzoogB.A. Tree of Life; Endothelial Cell Physiopathology, the Good Guy Is a Partner in Crime!Anat. Cell Biol.2023
    [Google Scholar]
  60. MarzoogB.A. Endothelial cell autophagy in the context of disease development.Anat. Cell Biol.2023561162410.5115/acb.22.09836267005
    [Google Scholar]
  61. MarzoogB.A. Local Lung Fibroblast Autophagy in the Context of Lung Fibrosis Pathogenesis.Curr. Respir. Med. Rev.202319161110.2174/1573398X19666221130141600
    [Google Scholar]
  62. MarzoogB. Lipid behavior in metabolic syndrome pathophysiology.Curr. Diabetes Rev.2022186e15092119649710.2174/157339981766621091510132134525924
    [Google Scholar]
  63. MarzoogB.A. Pulmonary fibrosis; risk factors and molecular triggers, insight for neo therapeutic approach.Curr. Respir. Med. Rev.202218425926610.2174/1573398X18666220806124019
    [Google Scholar]
  64. MarzoogB.A. Recent advances in molecular biology of metabolic syndrome pathophysiology: endothelial dysfunction as a potential therapeutic target.J. Diabetes Metab. Disord.20222121903191110.1007/s40200‑022‑01088‑y36065330
    [Google Scholar]
  65. MarzoogB.A. VlasovaT.I. Membrane lipids under norm and pathology.Euro. J. Clini. Exp. Medi.2021191597510.15584/ejcem.2021.1.9
    [Google Scholar]
  66. MarzoogB.A. VlasovaT.I. The metabolic syndrome puzzles; possible pathogenesis and management.Curr. Diabetes Rev.20221810.2174/157339981866622042910041135507784
    [Google Scholar]
  67. RebutiniP.Z. ZanchettinA.C. StonogaE.T.S. PráD.M.M. de OliveiraA.L.P. DezidérioF.S. FonsecaA.S. DagostiniJ.C.H. HlatchukE.C. FuruieI.N. LongoJ.S. CavalliB.M. DinoC.L.T. DiasV.M.C.H. PercicoteA.P. NogueiraM.B. RaboniS.M. de CarvalhoN.S. Machado-SouzaC. de NoronhaL. Association between COVID-19 Pregnant women symptoms severity and placental morphologic features.Front. Immunol.20211268591910.3389/fimmu.2021.68591934122449
    [Google Scholar]
  68. AghaamooS. GhodsK. RahmanianM. Pregnant women with COVID-19: the placental involvement and consequences.J. Mol. Histol.202152342743510.1007/s10735‑021‑09970‑433871721
    [Google Scholar]
  69. Ana OrostizagaA. Francisca ApablazaR. Bárbara GarridoL. Paulina ZúñigaF. Italo VaccarezzaP. WittkopfD. Case Report: Multidisciplinary Management in Case of 31 Weeks Pregnant Woman and COVID 19 Infection with Severe Disease Presentation | Reporte de Caso: Manejo Multidisciplinario En Gestante Con Embarazo de 31 Semanas y COVID-19 Positivo Con Evolución Grav.Rev. Chil. Obstet. Ginecol.202085S97S10010.4067/S0717‑75262020000700013
    [Google Scholar]
  70. AndrikopoulouM. MaddenN. WenT. AubeyJ.J. AzizA. BaptisteC.D. BreslinN. D’AltonM.E. FuchsK.M. GoffmanD. Gyamfi-BannermanC. Matseoane-PeterssenD.N. MillerR.S. SheenJ.J. SimpsonL.L. SuttonD. ZorkN. FriedmanA.M. Symptoms and Critical Illness Among Obstetric Patients With Coronavirus Disease 2019 (COVID-19) Infection.Obstet. Gynecol.2020136229129910.1097/AOG.000000000000399632459701
    [Google Scholar]
  71. Karimi-ZarchiM. NeamatzadehH. DastgheibS.A. AbbasiH. MirjaliliS.R. BehforouzA. FerdosianF. BahramiR. Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: A review.Fetal Pediatr. Pathol.202039324625010.1080/15513815.2020.174712032238084
    [Google Scholar]
  72. LiuW. ChengH. WangJ. DingL. ZhouZ. LiuS. ChangL. RongZ. Clinical analysis of neonates born to mothers with or without COVID-19: A retrospective analysis of 48 cases from two neonatal intensive care units in hubei province.Am. J. Perinatol.202037131317132310.1055/s‑0040‑171650532892325
    [Google Scholar]
  73. JomaM. FovetC.M. SeddikiN. GressensP. LaforgeM. COVID-19 and pregnancy: Vertical transmission and inflammation impact on newborns.Vaccines (Basel)20219439110.3390/vaccines904039133921113
    [Google Scholar]
  74. VivantiA.J. Vauloup-FellousC. PrevotS. ZupanV. SuffeeC. Do CaoJ. BenachiA. De LucaD. Transplacental transmission of SARS-CoV-2 infection.Nat. Commun.2020111357210.1038/s41467‑020‑17436‑632665677
    [Google Scholar]
  75. SchwartzD.A. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes.Arch. Pathol. Lab. Med.2020144779980510.5858/arpa.2020‑0901‑SA32180426
    [Google Scholar]
  76. GulersenM. PrasannanL. Tam TamH. MetzC.N. RochelsonB. MeirowitzN. ShanW. EdelmanM. MillingtonK.A. Histopathologic evaluation of placentas after diagnosis of maternal severe acute respiratory syndrome coronavirus 2 infection.Am. J. Obstet. Gynecol. MFM20202410021110.1016/j.ajogmf.2020.10021132838277
    [Google Scholar]
  77. SpringerD. JiskraJ. LimanovaZ. ZimaT. PotlukovaE. Thyroid in pregnancy: From physiology to screening.Crit. Rev. Clin. Lab. Sci.201754210211610.1080/10408363.2016.126930928102101
    [Google Scholar]
  78. AnaK.M.S. KarinaM.S. ThaílaC.C. Immunological aspects of pregnancy (Obzor Literature).J. Clin. Neonatol.201344313410.24966/NCP‑878X/100016
    [Google Scholar]
  79. VasilopoulouE. LoubièreL.S. LashG.E. OhizuaO. McCabeC.J. FranklynJ.A. KilbyM.D. ChanS.Y. Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner.Hum. Reprod.20142961161117210.1093/humrep/deu04624626803
    [Google Scholar]
  80. FerreiraG. BlasinaF. Rodríguez ReyM. AnesettiG. SapiroR. ChavarríaL. CardozoR. ReyG. SobreviaL. NicolsonG.L. Pathophysiological and molecular considerations of viral and bacterial infections during maternal-fetal and –neonatal interactions of SARS-CoV-2, Zika, and Mycoplasma infectious diseases.Biochim. Biophys. Acta Mol. Basis Dis.20221868116628510.1016/j.bbadis.2021.16628534624499
    [Google Scholar]
  81. Abbas-HanifA. RezaiH. AhmedS.F. AhmedA. The Impact of COVID-19 on Pregnancy and Therapeutic Drug Development.Br. J. Pharmacol.2022179102108212010.1111/bph.1558234085281
    [Google Scholar]
  82. MarzoogB. Anticoagulant status under COVID-19: The potential pathophysiological mechanism.J. App. Hematol.y202213416710.4103/joah.joah_154_21
    [Google Scholar]
  83. Organizm Women in Pregnancy: Extragenital Changes (Obzor Literature).In: Federal State Unitary Enterprise «Izdatelstvo Sibirskogo otsadeniya Rossiiskoi Akademii Nauk»2005
    [Google Scholar]
  84. MadjunkovM. DviriM. LibrachC. A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective.J. Ovarian Res.202013114010.1186/s13048‑020‑00737‑1
    [Google Scholar]
  85. ShatunovaP.O. BykovA.S. SvitichO.A. ZverevV.V. Angiotensin-converting enzyme 2. Approaches to pathogenetic therapy of COVID-19.Journal of microbiology, epidemiology and immunobiology202097433934510.36233/0372‑9311‑2020‑97‑4‑6
    [Google Scholar]
  86. AlloteyJ. FernandezS. BonetM. StallingsE. YapM. KewT. ZhouD. CoomarD. SheikhJ. LawsonH. AnsariK. AttardeS. LittmodenM. BanjokoA. BarryK. AkandeO. SambamoorthiD. van WelyM. van LeeuwenE. KostovaE. KunstH. KhalilA. TiberiS. BrizuelaV. BroutetN. KaraE. KimC.R. ThorsonA. EscurietR. GottliebS. TongV.T. EllingtonS. OladapoO.T. MofensonL. ZamoraJ. ThangaratinamS. for PregCOV-19 Living Systematic Review Consortium Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.BMJ2020370m332010.1136/bmj.m332032873575
    [Google Scholar]
  87. VousdenN. BunchK. MorrisE. SimpsonN. GaleC. O’BrienP. QuigleyM. BrocklehurstP. KurinczukJ.J. KnightM. The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: A national cohort study using the UK Obstetric Surveillance System (UKOSS).PLoS One2021165e025112310.1371/journal.pone.025112333951100
    [Google Scholar]
  88. Laresgoiti-ServitjeE. Cardona-PérezJ.A. Hernández-CruzR.G. COVID-19 infection in pregnancy: PCR cycle thresholds, placental pathology, and perinatal outcomes.Viruses202113918810.3390/v13091884
    [Google Scholar]
  89. Şahi̇nD. TanaçanA. WebsterS.N.E. Moraloğlu Teki̇nÖ. Pregnancy and COVID-19: prevention, vaccination, therapy, and beyond.Turk. J. Med. Sci.202151SI-13312332610.3906/sag‑2106‑134
    [Google Scholar]
  90. KarasekD. BaerR.J. McLemoreM.R. BellA.J. BlebuB.E. CaseyJ.A. Coleman-PhoxK. CostelloJ.M. FelderJ.N. FlowersE. FuchsJ.D. GomezA.M. KarvonenK. KuppermannM. LiangL. McKenzie-SampsonS. McCullochC.E. OltmanS.P. PantellM.S. PiaoX. PratherA.A. SchmidtR.J. ScottK.A. SpellenS. StookeyJ.D. TesfalulM. RandL. Jelliffe-PawlowskiL.L. The association of COVID-19 infection in pregnancy with preterm birth: A retrospective cohort study in California.Lancet Regional Health - Americas2021210002710.1016/j.lana.2021.10002734642685
    [Google Scholar]
  91. NanaM. Nelson-PiercyC. COVID-19 in Pregnancy.Clin. Med.2021215e44610.7861/clinmed.2021‑0503
    [Google Scholar]
  92. YanJ. GuoJ. FanC. JuanJ. YuX. LiJ. FengL. LiC. ChenH. QiaoY. LeiD. WangC. XiongG. XiaoF. HeW. PangQ. HuX. WangS. ChenD. ZhangY. PoonL.C. YangH. Coronavirus disease 2019 in pregnant women: a report based on 116 cases.Am. J. Obstet. Gynecol.20202231111.e1111.e1410.1016/j.ajog.2020.04.01432335053
    [Google Scholar]
  93. ElejeG.U. UgwuE.O. EnebeJ.T. OkoroC.C. OkpalaB.C. EzeoraN.C. IloghaluE.I. AnikweC.C. OkaforC.G. AguP.U. IgbodikeE.P. AkeI.D. EkwuaziK.E. OnwuegbunaA.A. UmeononihuO.S. AnaeduO.P. IkwukaD.C. NwaolisaH.I. NjokuC.C. NwankwoC.P. EmekaE.A. ElejeL.I. AdinnuK.M. OkoyeC.O. UgwuA.O. NwachukwuE.O. MbaS.G. EzenkweleE.P. OkoyeU.E. OfiaeliC.I. IkpezeG.C. OnahL.N. IkpezeO.Z. EjikemeT.B. UdigweG.O. IkechebeluJ.I. Cesarean section rate and outcomes during and before the first wave of COVID-19 pandemic.SAGE Open Med.20221010.1177/2050312122108545335342633
    [Google Scholar]
  94. BandyopadhyayD. AkhtarT. HajraA. GuptaM. DasA. ChakrabortyS. PalI. PatelN. AmgaiB. GhoshR.K. FonarowG.C. LavieC.J. NaiduS.S. COVID-19 Pandemic: Cardiovascular Complications and Future Implications.Am. J. Cardiovasc. Drugs202020431132410.1007/s40256‑020‑00420‑232578167
    [Google Scholar]
  95. MitraniR.D. DabasN. GoldbergerJ.J. COVID-19 cardiac injury: Implications for long-term surveillance and outcomes in survivors.Heart Rhythm202017111984199010.1016/j.hrthm.2020.06.02632599178
    [Google Scholar]
  96. JuuselaA. NazirM. GimovskyM. Two cases of coronavirus 2019–related cardiomyopathy in pregnancy.Am. J. Obstet. Gynecol. MFM20202210011310.1016/j.ajogmf.2020.10011332363336
    [Google Scholar]
  97. HammadW.A.B. Al BeloushiM. AhmedB. KonjeJ.C. Severe acute respiratory syndrome (SARS) coronavirus-2 infection (COVID-19) in pregnancy – An overview.Eur. J. Obstet. Gynecol. Reprod. Biol.202126310611610.1016/j.ejogrb.2021.06.00134225131
    [Google Scholar]
  98. Karimi-ZarchiM. SchwartzD.A. BahramiR. DastgheibS.A. JavaheriA. TabatabaieeR.S. FerdosianF. AsadianF. NeamatzadehH. A meta-analysis for the risk and prevalence of preeclampsia among pregnant women with COVID-19.J. Turkish Soci. Obstet. Gynecol.202118322423510.4274/tjod.galenos.2021.6675034580872
    [Google Scholar]
  99. RosenbloomJ.I. RaghuramanN. CarterE.B. KellyJ.C. Coronavirus disease 2019 infection and hypertensive disorders of pregnancy.Am. J. Obstet. Gynecol.2021224662362410.1016/j.ajog.2021.03.00133675794
    [Google Scholar]
  100. ZaighamM. AnderssonO. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies.Acta Obstet. Gynecol. Scand.202099782382910.1111/aogs.1386732259279
    [Google Scholar]
  101. DashraathP. WongJ.L.J. LimM.X.K. LimL.M. LiS. BiswasA. ChoolaniM. MattarC. SuL.L. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy.Am. J. Obstet. Gynecol.2020222652153110.1016/j.ajog.2020.03.02132217113
    [Google Scholar]
  102. Di MascioD. BucaD. BerghellaV. KhalilA. RizzoG. OdiboA. SacconeG. GalindoA. LiberatiM. D’AntonioF. Counseling in maternal–fetal medicine: SARS-CoV-2 infection in pregnancy.Ultrasound Obstet. Gynecol.202157568769710.1002/uog.2362833724545
    [Google Scholar]
  103. SiddiquiS. NajamR. Pregnancy outcomes with COVID-19 lessons learned from the pandemic.Cureus2021137e1635810.7759/cureus.1635834395135
    [Google Scholar]
  104. DeBoltC.A. BiancoA. LimayeM.A. SilversteinJ. PenfieldC.A. RomanA.S. RosenbergH.M. FerraraL. LambertC. KhouryR. BernsteinP.S. BurdJ. BerghellaV. KaplowitzE. OverbeyJ.R. StoneJ. Pregnant women with severe or critical coronavirus disease 2019 have increased composite morbidity compared with nonpregnant matched controls.Am. J. Obstet. Gynecol.20212245510.e1510.e1210.1016/j.ajog.2020.11.02233221292
    [Google Scholar]
  105. JafariM. PormohammadA. Sheikh NeshinS.A. GhorbaniS. BoseD. AlimohammadiS. BasirjafariS. MohammadiM. Rasmussen-IveyC. RazizadehM.H. Nouri-VaskehM. ZareiM. Clinical characteristics and outcomes of pregnant women with COVID-19 and comparison with control patients: A systematic review and meta-analysis.Rev. Med. Virol.202131511610.1002/rmv.220833387448
    [Google Scholar]
  106. MolteniE. AstleyC.M. MaW. SudreC.H. MageeL.A. MurrayB. FallT. GomezM.F. TsereteliN. FranksP.W. SARS-CoV-2 (COVID-19) infection in pregnant women: characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology.medRxiv20202020.08.17.2016176010.1101/2020.08.17.20161760
    [Google Scholar]
  107. AdhikariE.H. MorenoW. ZofkieA.C. MacDonaldL. McIntireD.D. CollinsR.R.J. SpongC.Y. Pregnancy outcomes among women with and without severe acute respiratory syndrome coronavirus 2 infection.JAMA Netw. Open2020311e202925610.1001/jamanetworkopen.2020.2925633211113
    [Google Scholar]
  108. Vergara-MerinoL. MezaN. Couve-PérezC. CarrascoC. Ortiz-MuñozL. MadridE. Bohorquez-BlancoS. Pérez-BracchiglioneJ. Maternal and perinatal outcomes related to COVID-19 and pregnancy: An overview of systematic reviews.Acta Obstet. Gynecol. Scand.202110071200121810.1111/aogs.1411833560530
    [Google Scholar]
  109. TaghaviS.A. HeidariS. JahanfarS. AmirjaniS. Aji-ramkaniA. Azizi-KutenaeeM. BazarganipourF. Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study.Middle East Fertil. Soc. J.20212611710.1186/s43043‑021‑00059‑234149282
    [Google Scholar]
  110. EdlowA.G. LiJ.Z. CollierA.Y. AtyeoC. JamesK.E. BoatinA.A. GrayK.J. BordtE.A. ShookL.L. YonkerL.M. FasanoA. DioufK. CroulN. DevaneS. YockeyL.J. LimaR. ShuiJ. MatuteJ.D. LerouP.H. AkinwunmiB.O. SchmidtA. FeldmanJ. HauserB.M. CaradonnaT.M. De la FlorD. D’AvinoP. ReganJ. CorryH. CoxenK. FajnzylberJ. PepinD. SeamanM.S. BarouchD.H. WalkerB.D. YuX.G. KaimalA.J. RobertsD.J. AlterG. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic.JAMA Netw. Open2020312e203045510.1001/jamanetworkopen.2020.3045533351086
    [Google Scholar]
  111. DelahoyM.J. WhitakerM. O’HalloranA. ChaiS.J. KirleyP.D. AldenN. KawasakiB. MeekJ. Yousey-HindesK. AndersonE.J. OpenoK.P. MonroeM.L. RyanP.A. FoxK. KimS. LynfieldR. SiebmanS. DavisS.S. SosinD.M. BarneyG. MuseA. BennettN.M. FelsenC.B. BillingL.M. ShiltzJ. SuttonM. WestN. SchaffnerW. TalbotH.K. GeorgeA. SpencerM. EllingtonS. GalangR.R. GilboaS.M. TongV.T. PiaseckiA. BrammerL. FryA.M. HallA.J. WorthamJ.M. KimL. GargS. ApostolM. BrooksS. CoatesA. FrankL. HeidengaB. HundalK. NadleJ. QuachS. RolandJ. RosalesM. ArmisteadI. HerlihyR. McLaffertyS. MisiorskiA. ParisiC. OlsonD. LyonsC. MaslarA. ClogherP. BlytheD. BrooksA. ParkR. WilsonM. ByeE. Como-SabettiK. DanilaR. SullivanM. AngelesK.M. ChristianM. EisenbergN. HabrunC. HancockE.B. KhanlianS.A. NoviM. Salazar-SanchezY. DufortE. SpinaN. Owusu-DommeyA. MarkusT. ChatelainR. McCulloughL. OrtegaJ. PriceA. SwainA. KambhampatiA. MeadorS. Characteristics and maternal and birth outcomes of hospitalized pregnant women with laboratory-confirmed COVID-19 — COVID-NET, 13 States, March 1–August 22, 2020.MMWR Morb. Mortal. Wkly. Rep.202069381347135410.15585/mmwr.mm6938e132970655
    [Google Scholar]
  112. AlzamoraM.C. ParedesT. CaceresD. WebbC.M. ValdezL.M. La RosaM. Severe COVID-19 during pregnancy and possible vertical transmission.Am. J. Perinatol.202037886186510.1055/s‑0040‑171005032305046
    [Google Scholar]
  113. SeyedAlinaghiS. MirzapourP. DadrasO. PashaeiZ. KarimiA. MohsseniPourM. SoleymanzadehM. BarzegaryA. AfsahiA.M. VahediF. ShamsabadiA. BehnezhadF. SaeidiS. MehraeenE. Shayesteh Jahanfar Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review.Eur. J. Med. Res.20212615110.1186/s40001‑021‑00524‑834103090
    [Google Scholar]
  114. SeyedAlinaghiS. AfsahiA.M. MohsseniPourM. BehnezhadF. SalehiM.A. BarzegaryA. MirzapourP. MehraeenE. DadrasO. Late complications of COVID-19; a systematic review of current evidence.Arch. Acad. Emerg. Med.202191e14e1410.22037/AAEM.V9I1.105833681819
    [Google Scholar]
  115. MarzoogB.A. Coagulopathy and brain injury pathogenesis in post-covid-19 syndrome.Cardiovasc. Hematol. Agents Med. Chem.202220317818810.2174/187152572066622040512402135382728
    [Google Scholar]
  116. VougaM. FavreG. Martinez-PerezO. PomarL. AcebalL.F. Abascal-SaizA. HernandezM.R.V. HciniN. LambertV. CarlesG. SichitiuJ. SalomonL. StirnemannJ. VilleY. de TejadaB.M. GoncéA. Hawkins-VillarrealA. CastilloK. SolsonaE.G. TrigoL. ClearyB. GearyM. BartelsH. Al-KharoufF. MaloneF. HigginsM. KeatingN. KnowlesS. PonceletC. Ribeiro-do-ValleC.C. SuritaF. Dantas-SilvaA. BorrelliC. LuzA.G. FuenzalidaJ. CarvajalJ. CanalesM.G. HernandezO. GrechukhinaO. KoA.I. ReddyU. FigueiredoR. MouchoM. PintoP.V. De LucaC. De SantisM. de CamposD.A. MartinsI. GarabedianC. SubtilD. BohrerB. Da Rocha OppermannM.L. WenderM.C.O. Schuler-FacciniL. SanseverinoM.T.V. GiuglianiC. FriedrichL. SchererM.H. MottetN. DucarmeG. PelerinH. MoreauC. BretonB. QuibelT. RozenbergP. GiannoniE. GranadoC. MonodC. MuellerD. HoesliI. BasslerD. HeldstabS. KölbleN.O. SentilhesL. CharvetM. DeprestJ. RichterJ. Van der VeekenL. Eggel-HortB. PlantefeveG. DerouichM. CalvacheA.J.N. Lopez-GironM.C. Burgos-LunaJ.M. Escobar-VidarteM.F. HecherK. TallarekA.C. HadarE. HaratzK.K. AmikamU. MalingerG. MaymonR. YogevY. SchäfferL. ToussaintA. RossierM.C. De SaR.A.M. GraweC. Aebi-PoppK. RadanA.P. RaioL. SurbekD. BöckenhoffP. StrizekB. KaufmannM. BlochA. BoulvainM. JohannS. HeldstabS.A. BernasconiM.T. GrantG. FekiA. BrochutA.C.M. GiralM. SedilleL. PapadiaA. BruggerR.C. WeberB. FischerT. KahlertC. SainesK.N. CambouM. KanellosP. ChenX. YinM. HaessigA. AckermannS. BaudD. PanchaudA. Maternal outcomes and risk factors for COVID-19 severity among pregnant women.Sci. Rep.20211111389810.1038/s41598‑021‑92357‑y34230507
    [Google Scholar]
  117. ChenT. WuD. ChenH. YanW. YangD. ChenG. MaK. XuD. YuH. WangH. WangT. GuoW. ChenJ. DingC. ZhangX. HuangJ. HanM. LiS. LuoX. ZhaoJ. NingQ. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study.BMJ2020368m109110.1136/bmj.m109132217556
    [Google Scholar]
  118. GrechukhinaO. GreenbergV. LundsbergL.S. DeshmukhU. CateJ. LipkindH.S. CampbellK.H. PettkerC.M. KohariK.S. ReddyU.M. Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population.Am. J. Obstet. Gynecol. MFM20202410024610.1016/j.ajogmf.2020.10024633047100
    [Google Scholar]
/content/journals/nemj/10.2174/0250688204666230519145707
Loading
/content/journals/nemj/10.2174/0250688204666230519145707
Loading

Data & Media loading...

Supplements

PRISMA checklist is available as supplementary material on the publisher’s website along with the published article.

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test