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image of A Case Report of Severe Hypothyroidism-induced Cardiomyopathy and Anemia: The Concealed Cause
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Abstract

Background:

Cardiomyopathies are a broad range of cardiac illnesses defined by mechanical and/or electrical dysfunction and abnormal ventricular hypertrophy or dilatation. Cardiomyopathies are classified into two categories: either primarily related to myocardial disease or secondary to other systemic or organ disorders, including the thyroid gland. Thyroid hormones have been linked to a wide range of significant effects on the cardiovascular system.

Case Presentation:

We experienced a case of a 37-year-old male who presented with symptoms of heart failure and was discovered to have dilated cardiomyopathy. The echocardiography study revealed significant left ventricular global hypokinesia and severely depressed left ventricular systolic function. The laboratory testing confirms the presence of severe normocytic, normochromic anemia with severe hypothyroidism.

Conclusion:

The present case illustrates that hypothyroidism should be addressed systematically by healthcare providers when dilated cardiomyopathy is identified, and thyroid function testing should be regularly performed.

2024 © 2024 The Author(s). Published by Bentham Science Publisher. The Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-12-24
2025-01-19

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References

  1. Maron B.J. Towbin J.A. Thiene G. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 2006 113 14 1807 1816 10.1161/CIRCULATIONAHA.106.174287
    [Google Scholar]
  2. Sisakian H. Cardiomyopathies: Evolution of pathogenesis concepts and potential for new therapies. World J. Cardiol. 2014 6 6 478 494 10.4330/wjc.v6.i6.478
    [Google Scholar]
  3. Udovcic M. Pena R.H. Patham B. Tabatabai L. Kansara A. Hypothyroidism and the Heart. Methodist DeBakey Cardiovasc. J. 2017 13 2 55 59 10.14797/mdcj‑13‑2‑55
    [Google Scholar]
  4. Bielecka-Dabrowa A. Godoy B. Suzuki T. Banach M. von Haehling S. Subclinical hypothyroidism and the development of heart failure: an overview of risk and effects on cardiac function. Clin. Res. Cardiol. 2019 108 3 225 233 10.1007/s00392‑018‑1340‑1
    [Google Scholar]
  5. Biondi B. Mechanisms in endocrinology: Heart failure and thyroid dysfunction. Eur. J. Endocrinol. 2012 167 5 609 618 10.1530/EJE‑12‑0627
    [Google Scholar]
  6. Klein I. Danzi S. Thyroid disease and the heart. Circulation 2007 116 15 1725 1735 10.1161/CIRCULATIONAHA.106.678326
    [Google Scholar]
  7. Zawadzka K Dziedzic R Surdacki A Chyrchel B. 2021
  8. Abdel-Moneim A. Gaber A.M. Gouda S. Osama A. Othman S.I. Allam G. Relationship of thyroid dysfunction with cardiovascular diseases: updated review on heart failure progression. Hormones (Athens) 2020 19 3 301 309 10.1007/s42000‑020‑00208‑8
    [Google Scholar]
  9. Biondi B. Cooper D.S. The clinical significance of subclinical thyroid dysfunction. Endocr. Rev. 2008 29 1 76 131 10.1210/er.2006‑0043
    [Google Scholar]
  10. Duntas L.H. Chiovato L. Cardiovascular Risk in Patients with Subclinical Hypothyroidism. Eur. Endocrinol. 2014 10 2 157 160 10.17925/EE.2014.10.02.157
    [Google Scholar]
  11. Kaushik A Agrawal M. Relationship Between Subclinical Hypothyroidism and the Risk of Cardiovascular Complications. 2023
    [Google Scholar]
  12. Zúñiga D Balasubramanian S Mehmood KT Al-Baldawi S Zúñiga Salazar G Hypothyroidism and Cardiovascular Disease: A Review. 2024
    [Google Scholar]
  13. Dorgalaleh A. Mahmoodi M. Varmaghani B. Effect of thyroid dysfunctions on blood cell count and red blood cell indice. Iran. J. Ped. Hematol. Oncol. 2013 3 2 73 77
    [Google Scholar]
  14. Soliman AT De Sanctis V Yassin M Wagdy M Soliman N Chronic anemia and thyroid function. 2017
    [Google Scholar]
  15. Szczepanek-Parulska E. Hernik A. Ruchała M. Anemia in thyroid diseases. Pol Arch Intern Med. 2017 127 5 352 360 10.20452/pamw.3985
    [Google Scholar]
  16. Cappola A.R. Desai A.S. Medici M. Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment. Circulation 2019 139 25 2892 2909 10.1161/CIRCULATIONAHA.118.036859
    [Google Scholar]
  17. Wilson S.A. Stem L.A. Bruehlman R.D. Hypothyroidism: Diagnosis and Treatment. Am. Fam. Physician 2021 103 10 605 613
    [Google Scholar]
  18. Dhir G. Jain V. Merritt A. Thyroid Disorders. Prim. Care 2024 51 3 405 415 10.1016/j.pop.2024.04.001
    [Google Scholar]
  19. Rastogi P. Dua A. Attri S. Sharma H. Hypothyroidism-induced reversible dilated cardiomyopathy. J. Postgrad. Med. 2018 64 3 177 179 10.4103/jpgm.JPGM_154_17
    [Google Scholar]
  20. Nakova V.V. Krstevska B. Kostovska E.S. Vaskova O. Ismail L.G. The effect of levothyroxine treatment on left ventricular function in subclinical hypothyroidism. Arch. Endocrinol. Metab. 2018 62 4 392 398 10.20945/2359‑3997000000052
    [Google Scholar]
  21. Ladenson P.W. Sherman S.I. Baughman K.L. Ray P.E. Feldman A.M. Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism. Proc. Natl. Acad. Sci. USA 1992 89 12 5251 5255 [published correction appears in Proc Natl Acad Sci U S A 1992 Sep 15;89(18):8856]. 10.1073/pnas.89.12.5251
    [Google Scholar]
/content/journals/nemj/10.2174/0102506882363676241219043835
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A Case Report of Severe Hypothyroidism-induced Cardiomyopathy and Anemia: The Concealed Cause
Bentham Science Publishers , e02506882363676; https://doi.org/10.2174/0102506882363676241219043835
/content/journals/nemj/10.2174/0102506882363676241219043835
/content/journals/nemj/10.2174/0102506882363676241219043835
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  • Article Type:     Case Report
Keywords: Hypothyroidism ; Thyroid gland disorder ; Heart failure ; Anemia ; Dilated cardiomyopathy

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