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Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882
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Abstract

Aim

To evaluate the suitability of commercially available glucometers in the UAE in terms of accurate and reliable blood glucose measurements.

Background

Portable glucometers are employed for measuring blood glucose levels, offering distinct advantages such as providing instant results and being user-friendly when compared to laboratory reference analyzers. However, certain molecules, such as those found in medications, can interfere with the accuracy of glucometer readings.

Objective

To evaluate the precision and interference in the presence of maltose and vitamin C of three glucometers commercially available in the UAE.

Methods

We utilized plasma samples to conduct two types of experiments: a precision experiment and an interference experiment. We compared the precision of three glucometer brands available in the United Arab Emirates [Accu-Chek InstantTM, One Touch Select Plus FlexTM, and Trister GlucoScanTM] in the presence or not of various interfering molecules, such as Maltose and Ascorbic Acid (Vitamin C).

Results

Accu-Chek InstantTM demonstrated the highest precision among the glucometers tested, with a coefficient of variation of less than 5% for all measured glucose values. In contrast, OneTouch Select Plus FlexTM and Trister GlucoscanTM exhibited higher variability in precision, with coefficients of variation of 11.4% and 11%, respectively. Accu-Chek InstantTM consistently performed well in terms of bias and precision in the presence of interferences, and does not display glucose readings above 50mg/dL of Vitamin C. Notably, Ascorbic acid induced a greater bias compared to Maltose for all three glucometers.

Conclusion

The performance of the glucometer is affected by its testing methodology. Accu-Chek InstantTM shows improved precision and is able to detect the presence of Vitamin C. When it comes to Maltose interference, it results in a higher bias change but lower variability, which can be addressed by applying a correction factor.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-09-23
2025-01-31

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/content/journals/nemj/10.2174/0102506882321867240916045145
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Comparative Study on Precision and Interference of Maltose and Vitamin C among three Glucometers Commonly Used in United Arab Emirates (U.A.E)
NEW Emirates Medical J 5, e02506882321867 (2024); https://doi.org/10.2174/0102506882321867240916045145
/content/journals/nemj/10.2174/0102506882321867240916045145
/content/journals/nemj/10.2174/0102506882321867240916045145
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  • Article Type:     Research Article
Keyword(s): Accuracy; Ascorbic Acid; Glucometers; Interference; Maltose; Precision; United Arab Emirates

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