Skip to content
2000
Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882

Abstract

Annual seasonal influenza has been commonly experienced in most parts of the world since it was first introduced in 1968. The Influenza virus has been evolving genetically with time, which makes an escape into the host cell easier. The H1N1 Influenza pandemic started in 1918; by 1957, H1N1 was replaced by H2N2; following this, H3N2 emerged in 1968, replacing H2N2; in 2009, the H1N1 influenza re-emerged and lasted up to 2019. The increasing cases of the Influenza virus have consistently indicated a sudden re-emergence of a pandemic. To provide a perspective overview of the re-emergence of the Influenza pandemic. With published literature from the past. All studies have been extracted from widely referred databases, such as PubMed and Embase. This data has been extracted in a text file by running several strategic individual searches using specific MeSH terms. In the contemporary world, influenza is still a constant threat. Because of the virus's fast mutation rate due to antigenic drift and shift, increased international travel, and urbanization, it is crucial to have effective surveillance, early diagnosis, and quick reaction mechanisms. Public health initiatives, antiviral medications, and vaccination efforts are essential for reducing the effects of seasonal epidemics and possible pandemics. The resurgence of the influenza virus underscores the need for prioritizing readiness and teamwork. With the help of scientific and technological developments and lessons learned from history, we can lessen the effects of future outbreaks. This finding opens up new avenues for investigation and provides insight into the possibility of pandemic recurrence in the future.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/nemj/10.2174/0102506882291440240101075435
2024-01-26
2025-01-19
Loading full text...

Full text loading...

/deliver/fulltext/nemj/5/1/NEMJ-5-E02506882291440.html?itemId=/content/journals/nemj/10.2174/0102506882291440240101075435&mimeType=html&fmt=ahah

References

  1. AllenJ.D. RossT.M. H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation.Hum. Vaccin. Immunother.20181481840184710.1080/21645515.2018.146263929641358
    [Google Scholar]
  2. JesterB.J. UyekiT.M. JerniganD.B. Fifty years of influenza A(H3N2) following the pandemic of 1968.Am. J. Public Health2020110566967610.2105/AJPH.2019.30555732267748
    [Google Scholar]
  3. SampathS. KhedrA. QamarS. TekinA. SinghR. GreenR. KashyapR. Pandemics throughout the history.Cureus2021139e1813634692344
    [Google Scholar]
  4. JinjarakY. NoyI. TaQ. Pandemics and economic growth: Evidence from the 1968 H3N2 influenza.Econ. Disaster. Clim. Chang.202261739310.1007/s41885‑021‑00096‑134661047
    [Google Scholar]
  5. SpreeuwenbergP. KronemanM. PagetJ. Reassessing the global mortality burden of the 1918 influenza pandemic.Am. J. Epidemiol.2018187122561256710.1093/aje/kwy19130202996
    [Google Scholar]
  6. TaubenbergerJ.K. MorensD.M. The pathology of influenza virus infections.Annu. Rev. Pathol.20083149952210.1146/annurev.pathmechdis.3.121806.15431618039138
    [Google Scholar]
  7. AkinL. GözelM.G. Understanding dynamics of pandemics.Turk. J. Med. Sci.202050SI-151551910.3906/sag‑2004‑13332299204
    [Google Scholar]
  8. PhippsK.L. MarshallN. TaoH. DanzyS. OnuohaN. SteelJ. LowenA.C. Seasonal H3N2 and 2009 pandemic H1N1 influenza a viruses reassort efficiently but produce attenuated progeny.J. Virol.20179117e00830-1710.1128/JVI.00830‑1728637755
    [Google Scholar]
  9. BaralS.D. RucinskiK.B. Twahirwa RwemaJ.O. RaoA. Prata MenezesN. DioufD. KamarulzamanA. Phaswana-MafuyaN. MishraS. The relationship between the global burden of influenza from 2017 to 2019 and COVID-19: Descriptive epidemiological assessment.JMIR Public Health Surveill.202173e2469610.2196/2469633522974
    [Google Scholar]
  10. ZanobiniP. BonaccorsiG. LoriniC. HaagM. McGovernI. PagetJ. CainiS. Global patterns of seasonal influenza activity, duration of activity and virus (sub)type circulation from 2010 to 2020.Influenza Other Respir. Viruses202216469670610.1111/irv.1296935212157
    [Google Scholar]
  11. NelsonM.I. SouzaC.K. TrovãoN.S. DiazA. MenaI. RoviraA. VincentA.L. TorremorellM. MarthalerD. CulhaneM.R. Human-origin influenza A(H3N2) reassortant viruses in Swine, Southeast Mexico.Emerg. Infect. Dis.201925469170010.3201/eid2504.18077930730827
    [Google Scholar]
  12. LiuM. BakkerA.S. NarimatsuY. van KuppeveldF.J.M. ClausenH. de HaanC.A.M. de VriesE. H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic.Proc. Natl. Acad. Sci.202312031e230499212010.1073/pnas.230499212037467282
    [Google Scholar]
  13. BoppanaH. AdhitK.K. KutikuppalaL.V.S. MohapatraR.K. E-ZahanK. The recent H3N2 viral outbreak in India, 2023: Is it worrying?Health Sci. Rep.202367e141710.1002/hsr2.141737448731
    [Google Scholar]
  14. LinaB. History of influenza pandemics.PaleomicrobiologySpringer200819921110.1007/978‑3‑540‑75855‑6_12
    [Google Scholar]
  15. BercheP. The enigma of the 1889 Russian flu pandemic: A coronavirus?Presse Med.202251310411110.1016/j.lpm.2022.10411135124103
    [Google Scholar]
  16. Hajj HusseinI. ChamsN. ChamsS. El SayeghS. BadranR. RaadM. Gerges-GeageaA. LeoneA. JurjusA. Vaccines through centuries: Major cornerstones of global health.Front. Public Health2015326910.3389/fpubh.2015.0026926636066
    [Google Scholar]
  17. MartiniM. GazzanigaV. BragazziN.L. BarberisI. The Spanish influenza pandemic: A lesson from history 100 years after 1918.J. Prev. Med. Hyg.2019601E64E6731041413
    [Google Scholar]
  18. HonigsbaumM. Revisiting the 1957 and 1968 influenza pandemics.Lancet2020395102401824182610.1016/S0140‑6736(20)31201‑032464113
    [Google Scholar]
  19. SharmaA. GhoshD. DivekarN. GoreM. GochhaitS. ShireshiS.S. Comparing the socio‐economic implications of the 1918 Spanish flu and the COVID‐19 pandemic in India: A systematic review of literature.Int. Soc. Sci. J.202171S1233610.1111/issj.1226634230684
    [Google Scholar]
  20. FongI.W. Animals and Mechanisms of Disease Transmission.Emerging Zoonoses2017396110.1007/978‑3‑319‑50890‑0_3
    [Google Scholar]
  21. PepinKM HopkenMW ShrinerSA Improving risk assessment of the emergence of novel influenza A viruses by incorporating environmental surveillance.Philos Trans R Soc Lond B Biol Sci.201937417822018034610.1098/rstb.2018.0346
    [Google Scholar]
  22. KolosovaN.P. IlyichevaT.N. UnguryanV.V. DanilenkoA.V. SvyatchenkoS.V. OnhonovaG.S. GoncharovaN.I. KosenkoM.N. GudymoA.S. MarchenkoV.Y. ShvalovA.N. SusloparovI.M. TregubchakT.V. GavrilovaE.V. MaksyutovR.A. RyzhikovA.B. Re-emergence of circulation of seasonal influenza during COVID-19 pandemic in Russia and receptor specificity of new and dominant clade 3C.2a1b.2a.2 A(H3N2) viruses in 2021–2022.Pathogens20221111138810.3390/pathogens1111138836422639
    [Google Scholar]
  23. KimH. WebsterR.G. WebbyR.J. Influenza virus: Dealing with a drifting and shifting pathogen.Viral Immunol.201831217418310.1089/vim.2017.014129373086
    [Google Scholar]
  24. CoullietteA.D. PerryK.A. EdwardsJ.R. Noble-WangJ.A. Persistence of the 2009 pandemic influenza A (H1N1) virus on N95 respirators.Appl. Environ. Microbiol.20137972148215510.1128/AEM.03850‑1223335770
    [Google Scholar]
  25. DawoodF.S. JainS. FinelliL. ShawM.W. LindstromS. GartenR.J. GubarevaL.V. XuX. BridgesC.B. UyekiT.M. Emergence of a novel swine-origin influenza A (H1N1) virus in humans.N. Engl. J. Med.2009360252605261510.1056/NEJMoa090381019423869
    [Google Scholar]
  26. KangM. ZaninM. WongS.S. Subtype H3N2 influenza a viruses: An unmet challenge in the Western pacific.Vaccines202210111210.3390/vaccines1001011235062773
    [Google Scholar]
  27. KesslerS. HarderT. SchwemmleM. CiminskiK. InfluenzaA. Influenza a viruses and zoonotic events—are we creating our own reservoirs?Viruses20211311225010.3390/v1311225034835056
    [Google Scholar]
  28. AbdelwhabE.M. MettenleiterT.C. Zoonotic animal influenza virus and potential mixing vessel hosts.Viruses202315498010.3390/v1504098037112960
    [Google Scholar]
  29. LimP.L. Travel and the globalization of emerging infections.Trans. R. Soc. Trop. Med. Hyg.2014108630931010.1093/trstmh/tru05124835690
    [Google Scholar]
  30. GoumaS. AndersonE.M. HensleyS.E. Challenges of making effective influenza vaccines.Annu. Rev. Virol.20207149551210.1146/annurev‑virology‑010320‑04474632392457
    [Google Scholar]
  31. MadsenA. CoxR.J. Prospects and challenges in the development of universal influenza vaccines.Vaccines20208336110.3390/vaccines803036132640619
    [Google Scholar]
  32. RomanelliR.J. CablingM. Marciniak-NuquiZ. MarjanovicS. MorrisS. DufresneE. YerushalmiE. The societal and indirect economic burden of seasonal influenza in the United Kingdom.Rand Health Q.2023104237720072
    [Google Scholar]
  33. HagiwaraY. HaradaK. NealonJ. OkumuraY. KimuraT. ChavesS.S. Seasonal influenza, its complications and related healthcare resource utilization among people 60 years and older: A descriptive retrospective study in Japan.PLoS One20221710e027279510.1371/journal.pone.027279536191012
    [Google Scholar]
  34. BchetniaM. GirardC. DuchaineC. LapriseC. The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A review of the current global status.J. Infect. Public Health202013111601161010.1016/j.jiph.2020.07.01132778421
    [Google Scholar]
  35. SomininaA. DanilenkoD. KomissarovA.B. PisarevaM. FadeevA. KonovalovaN. EropkinM. PetrovaP. ZheltukhinaA. MusaevaT. EderV. IvanovaA. KomissarovaK. StolyarovK. KarpovaL. SmorodintsevaE. DoroshA. KrivitskayaV. KuznetzovaE. MajorovaV. PetrovaE. BoyarintsevaA. KsenafontovA. ShtroA. NikolaevaJ. BakaevM. BurtsevaE. LioznovD. Assessing the intense influenza A(H1N1)pdm09 epidemic and vaccine effectiveness in the post-COVID season in the russian federation.Viruses2023158178010.3390/v1508178037632122
    [Google Scholar]
  36. DudinG.A. AzizI.M. AlzayedR.M. AhmedA. HussainT. SomilyA.M. AlsaadiM.M. AlmajhdiF.N. Genetic diversity and evolutionary kinetics of influenza a virus H3N2 subtypes circulating in Riyadh, Saudi Arabia.Vaccines202311370210.3390/vaccines1103070236992286
    [Google Scholar]
  37. GalliC. PellegrinelliL. GiardinaF. FerrariG. Uceda RenteriaS.C. NovazziF. MasiE. PaganiE. PiccirilliG. MauroM.V. BindaS. CorvaroB. TiberioC. LalleE. MaggiF. RussoC. RannoS. VianE. ParianiE. BaldantiF. PirallaA. On the lookout for influenza viruses in Italy during the 2021-2022 season: Along came A(H3N2) viruses with a new phylogenetic makeup of their hemagglutinin.Virus Res.202332419903310.1016/j.virusres.2022.19903336581046
    [Google Scholar]
  38. VoraA. ShaikhA. Awareness, attitude, and current practices toward influenza vaccination among physicians in India: A multicenter, cross-sectional study.Front. Public Health2021964263610.3389/fpubh.2021.64263634497789
    [Google Scholar]
  39. JavanianM. BararyM. GhebrehewetS. KoppoluV. VasigalaV. EbrahimpourS. A brief review of influenza virus infection.J. Med. Virol.20219384638464610.1002/jmv.2699033792930
    [Google Scholar]
  40. NuwardaR.F. AlharbiA.A. KayserV. An overview of influenza viruses and vaccines.Vaccines202199103210.3390/vaccines909103234579269
    [Google Scholar]
/content/journals/nemj/10.2174/0102506882291440240101075435
Loading
/content/journals/nemj/10.2174/0102506882291440240101075435
Loading

Data & Media loading...


  • Article Type:
    Review Article
Keyword(s): H3N2 virus; History; Infectious diseases; Influenza; Novel strains; Pandemic; Re-emergence
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test