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Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882
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Abstract

Background

The prevalence of dyslipidemia in the United Arab Emirates (UAE) can be as high as 72.5%. Patients with dyslipidemia usually present with other metabolic risk factors, increasing their risk of acute cardiovascular diseases (CVD). Despite these alarming findings, local data regarding management practices in the UAE are lacking. The current report gathered the perspectives of experts from the UAE regarding the burden and current practices in managing dyslipidemia, as well as the current unmet needs and treatment gaps.

Methods

The present perspective is based on a consensus meeting that gathered the insights of six consultant cardiologists. All experts were affiliated with academic institutions representing the UAE's different geographical areas.

Findings and Conclusion

Data regarding the prevalence of dyslipidemia in the UAE and its associated ethnic differences are lacking. It is suggested that there needs to be more adherence to international recommendations for screening lipid profiles in primary care centers, which may lead to underestimating the burden of dyslipidemia. As CVD presents at a younger age in the UAE, screening for lipid profile at 35 is recommended, regardless of CVD risk. The panel emphasized that most dyslipidemia patients in the UAE are categorized as high or very high-risk groups for CVD; however, current risk assessment tools have not been validated in the UAE population and may not be tailored to the Middle Eastern and Asian populations. International guidelines have recommended the high-intensity statins-ezetimibe combination for high and very high-risk patients; the experts stated that the high-intensity statins-ezetimibe combination could be initiated in high-risk groups in the UAE. Several barriers to effectively controlling dyslipidemia in the UAE have been identified, including non-adherence, limited awareness about screening and management recommendations, and physician inertia toward achieving the recommended therapeutic goals.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-04-23

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References

  1. BhagavathulaA.S. ShehabA. UllahA. RahmaniJ. The burden of cardiovascular disease risk factors in the Middle East: A systematic review and meta-analysis focusing on primary prevention.Curr. Vasc. Pharmacol.202119437938910.2174/157340641666620061110414332525775
     [Google Scholar]
  2. World Health OrganizationCardiovascular diseases.Available From: https://www.who.int/health-topics/cardiovascular-diseases/#tab=tab_1
  3. MotlaghB. O’DonnellM. YusufS. Prevalence of cardiovascular risk factors in the Middle East: A systematic review.Eur. J. Cardiovasc. Prev. Rehabil.200916326828010.1097/HJR.0b013e328322ca1b19398913
     [Google Scholar]
  4. AlmahmeedW. ArnaoutM.S. ChettaouiR. IbrahimM. KurdiM.I. TaherM.A. ManciaG. Coronary artery disease in Africa and the Middle East.Ther. Clin. Risk Manag.20128657210.2147/TCRM.S2641422368447
     [Google Scholar]
  5. MahmoudI. SulaimanN. Dyslipidaemia prevalence and associated risk factors in the United Arab Emirates: A population-based study.BMJ Open2019911e03196910.1136/bmjopen‑2019‑03196931699740
     [Google Scholar]
  6. VosT. LimS.S. AbbafatiC. AbbasK.M. AbbasiM. AbbasifardM. Abbasi-KangevariM. AbbastabarH. Abd-AllahF. AbdelalimA. AbdollahiM. AbdollahpourI. AbolhassaniH. AboyansV. AbramsE.M. AbreuL.G. AbrigoM.R.M. Abu-RaddadL.J. AbushoukA.I. AcebedoA. AckermanI.N. AdabiM. AdamuA.A. AdebayoO.M. AdekanmbiV. AdelsonJ.D. AdetokunbohO.O. AdhamD. AfshariM. AfshinA. AgardhE.E. AgarwalG. AgesaK.M. AghaaliM. AghamirS.M.K. AgrawalA. AhmadT. AhmadiA. AhmadiM. AhmadiehH. AhmadpourE. AkaluT.Y. AkinyemiR.O. AkinyemijuT. AkombiB. Al-AlyZ. AlamK. AlamN. AlamS. AlamT. AlanziT.M. AlbertsonS.B. Alcalde-RabanalJ.E. AlemaN.M. AliM. AliS. AlicandroG. AlijanzadehM. AliniaC. AlipourV. AljunidS.M. AllaF. AllebeckP. Almasi-HashianiA. AlonsoJ. Al-RaddadiR.M. AltirkawiK.A. Alvis-GuzmanN. Alvis-ZakzukN.J. AminiS. Amini-RaraniM. AminorroayaA. AmiriF. AmitA.M.L. AmugsiD.A. AmulG.G.H. AnderliniD. AndreiC.L. AndreiT. AnjomshoaM. AnsariF. AnsariI. Ansari-MoghaddamA. AntonioC.A.T. AntonyC.M. AntriyandartiE. AnvariD. AnwerR. ArablooJ. Arab-ZozaniM. AravkinA.Y. ArianiF. ÄrnlövJ. AryalK.K. ArzaniA. Asadi-AliabadiM. Asadi-PooyaA.A. AsghariB. AshbaughC. AtnafuD.D. AtreS.R. AusloosF. AusloosM. Ayala QuintanillaB.P. AyanoG. AyanoreM.A. AynalemY.A. AzariS. AzarianG. AzeneZ.N. BabaeeE. BadawiA. BagherzadehM. BakhshaeiM.H. BakhtiariA. BalakrishnanS. BalallaS. BalassyanoS. BanachM. BanikP.C. BannickM.S. BanteA.B. BarakiA.G. BarbozaM.A. Barker-ColloS.L. BarthelemyC.M. BaruaL. BarzegarA. BasuS. BauneB.T. BayatiM. BazmandeganG. BediN. BeghiE. BéjotY. BelloA.K. BenderR.G. BennettD.A. BennittF.B. BensenorI.M. BenzigerC.P. BerheK. BernabeE. BertolacciG.J. BhageerathyR. BhalaN. BhandariD. BhardwajP. BhattacharyyaK. BhuttaZ.A. BibiS. BiehlM.H. BikbovB. Bin SayeedM.S. BiondiA. BirihaneB.M. BisanzioD. BisignanoC. BiswasR.K. BohlouliS. BohluliM. BollaS.R.R. BoloorA. Boon-DooleyA.S. BorgesG. BorzìA.M. BourneR. BradyO.J. BrauerM. BrayneC. BreitbordeN.J.K. BrennerH. BriantP.S. BriggsA.M. BrikoN.I. BrittonG.B. BryazkaD. BuchbinderR. BumgarnerB.R. BusseR. ButtZ.A. Caetano dos SantosF.L. CámeraL.L.A.A. Campos-NonatoI.R. CarJ. CárdenasR. CarrerasG. CarreroJ.J. CarvalhoF. Castaldelli-MaiaJ.M. Castañeda-OrjuelaC.A. CastelpietraG. CastleC.D. CastroF. Catalá-LópezF. CauseyK. CederrothC.R. CercyK.M. CerinE. ChandanJ.S. ChangA.R. CharlsonF.J. ChattuV.K. ChaturvediS. Chimed-OchirO. ChinK.L. ChoD.Y. ChristensenH. ChuD-T. ChungM.T. CicuttiniF.M. CiobanuL.G. CirilloM. CollinsE.L. ComptonK. ContiS. CortesiP.A. CostaV.M. CousinE. CowdenR.G. CowieB.C. CromwellE.A. CrossD.H. CroweC.S. CruzJ.A. CunninghamM. DahlawiS.M.A. DamianiG. DandonaL. DandonaR. DarweshA.M. DaryaniA. DasJ.K. Das GuptaR. das NevesJ. Dávila-CervantesC.A. DavletovK. De LeoD. DeanF.E. DeCleeneN.K. DeenA. DegenhardtL. DellavalleR.P. DemekeF.M. DemsieD.G. Denova-GutiérrezE. DerejeN.D. DervenisN. DesaiR. DesalewA. DessieG.A. DharmaratneS.D. DhunganaG.P. DianatinasabM. DiazD. Dibaji ForooshaniZ.S. DingelsZ.V. DiracM.A. DjalaliniaS. DoH.T. DokovaK. DorostkarF. DoshiC.P. DoshmangirL. DouiriA. DoxeyM.C. DriscollT.R. DunachieS.J. DuncanB.B. DuraesA.R. EaganA.W. Ebrahimi KalanM. EdvardssonD. EhrlichJ.R. El NahasN. El SayedI. El TantawiM. ElbaraziI. ElgendyI.Y. ElhabashyH.R. El-JaafaryS.I. ElyazarI.R.F. EmamianM.H. Emmons-BellS. ErskineH.E. EshratiB. EskandariehS. EsmaeilnejadS. EsmaeilzadehF. EsteghamatiA. EstepK. EtemadiA. EtissoA.E. FarahmandM. FarajA. FareedM. FaridniaR. FarinhaC.S.S. FarioliA. FaroA. FaruqueM. FarzadfarF. FattahiN. FazlzadehM. FeiginV.L. FeldmanR. FereshtehnejadS-M. FernandesE. FerrariA.J. FerreiraM.L. FilipI. FischerF. FisherJ.L. FitzgeraldR. FlohrC. FlorL.S. FoigtN.A. FolayanM.O. ForceL.M. FornariC. ForoutanM. FoxJ.T. FreitasM. FuW. FukumotoT. FurtadoJ.M. GadM.M. GakidouE. GallesN.C. GallusS. GamkrelidzeA. Garcia-BasteiroA.L. GardnerW.M. GeberemariyamB.S. GebrehiwotA.M. GebremedhinK.B. GebreslassieA.A.A.A. Gershberg HayoonA. GethingP.W. GhadimiM. GhadiriK. GhafourifardM. GhajarA. GhamariF. GhashghaeeA. GhiasvandH. GhithN. GholamianA. GilaniS.A. GillP.S. GitimoghaddamM. GiussaniG. GoliS. GomezR.S. GopalaniS.V. GoriniG. GormanT.M. GottlichH.C. GoudarziH. GoulartA.C. GoulartB.N.G. GradaA. GrivnaM. GrossoG. GubariM.I.M. GugnaniH.C. GuimaraesA.L.S. GuimarãesR.A. GuledR.A. GuoG. GuoY. GuptaR. HaagsmaJ.A. HaddockB. Hafezi-NejadN. HafizA. HaginsH. HaileL.M. HallB.J. HalvaeiI. HamadehR.R. Hamagharib AbdullahK. HamiltonE.B. HanC. HanH. HankeyG.J. HaroJ.M. HarveyJ.D. HasaballahA.I. HasanzadehA. HashemianM. HassanipourS. HassankhaniH. HavmoellerR.J. HayR.J. HayS.I. HayatK. HeidariB. HeidariG. Heidari-SoureshjaniR. HendrieD. HenriksonH.J. HenryN.J. HerteliuC. HeydarpourF. HirdT.R. HoekH.W. HoleM.K. HollaR. HoogarP. HosgoodH.D. HosseinzadehM. HostiucM. HostiucS. HousehM. HoyD.G. HsairiM. HsiehV.C. HuG. HudaT.M. HugoF.N. HuynhC.K. HwangB-F. IannucciV.C. IbitoyeS.E. IkutaK.S. IlesanmiO.S. IlicI.M. IlicM.D. InbarajL.R. IppolitoH. IrvaniS.S.N. IslamM.M. IslamM.M. IslamS.M.S. IslamiF. IsoH. IversR.Q. IwuC.C.D. IyamuI.O. JaafariJ. JacobsenK.H. Jadidi-NiaraghF. JafariH. JafariniaM. JahagirdarD. JahaniM.A. JahanmehrN. JakovljevicM. JalaliA. JalilianF. JamesS.L. JanjaniH. JanodiaM.D. JayatillekeA.U. JeemonP. JenabiE. JhaR.P. JhaV. JiJ.S. JiaP. JohnO. John-AkinolaY.O. JohnsonC.O. JohnsonS.C. JonasJ.B. JooT. JoshiA. JozwiakJ.J. JürissonM. KabirA. KabirZ. KalaniH. KalaniR. KalankeshL.R. KalhorR. KamiabZ. KanchanT. Karami MatinB. KarchA. KarimM.A. KarimiS.E. KassaG.M. KassebaumN.J. KatikireddiS.V. KawakamiN. KayodeG.A. KeddieS.H. KellerC. KereselidzeM. KhafaieM.A. KhalidN. KhanM. KhatabK. KhaterM.M. KhatibM.N. KhayamzadehM. KhodayariM.T. KhundkarR. KianipourN. KielingC. KimD. KimY-E. KimY.J. KimokotiR.W. KisaA. KisaS. Kissimova-SkarbekK. KivimäkiM. KneibC.J. KnudsenA.K.S. KocarnikJ.M. KololaT. KopecJ.A. KosenS. KoulP.A. KoyanagiA. KravchenkoM.A. KrishanK. KrohnK.J. Kuate DefoB. Kucuk BicerB. KumarG.A. KumarM. KumarP. KumarV. KumareshG. KurmiO.P. KusumaD. KyuH.H. La VecchiaC. LaceyB. LalD.K. LallooR. LamJ.O. LamiF.H. LandiresI. LangJ.J. LansinghV.C. LarsonS.L. LarssonA.O. LasradoS. LassiZ.S. LauK.M-M. LavadosP.M. LazarusJ.V. LedesmaJ.R. LeeP.H. LeeS.W.H. LeGrandK.E. LeighJ. LeonardiM. LescinskyH. LeungJ. LeviM. LewingtonS. LiS. LimL-L. LinC. LinR-T. LinehanC. LinnS. LiuH-C. LiuS. LiuZ. LookerK.J. LopezA.D. LopukhovP.D. LorkowskiS. LotufoP.A. LucasT.C.D. LugoA. LuneviciusR. LyonsR.A. MaJ. MacLachlanJ.H. MaddisonE.R. MaddisonR. MadottoF. MahashaP.W. MaiH.T. MajeedA. MaledV. MalekiS. MalekzadehR. MaltaD.C. MamunA.A. ManafiA. ManafiN. ManguerraH. MansouriB. MansourniaM.A. Mantilla HerreraA.M. MaravillaJ.C. MarksA. Martins-MeloF.R. MartopulloI. MasoumiS.Z. MassanoJ. MassenburgB.B. MathurM.R. MaulikP.K. McAlindenC. McGrathJ.J. McKeeM. MehndirattaM.M. MehriF. MehtaK.M. MeiteiW.B. MemiahP.T.N. MendozaW. MenezesR.G. MengeshaE.W. MengeshaM.B. MerekeA. MeretojaA. MeretojaT.J. MestrovicT. MiazgowskiB. MiazgowskiT. MichalekI.M. MihretieK.M. MillerT.R. MillsE.J. MiricaA. MirrakhimovE.M. MirzaeiH. MirzaeiM. Mirzaei-AlavijehM. MisganawA.T. MithraP. MoazenB. MoghadaszadehM. MohamadiE. MohammadD.K. MohammadY. Mohammad Gholi MezerjiN. Mohammadian-HafshejaniA. MohammadifardN. MohammadpourhodkiR. MohammedS. MokdadA.H. MolokhiaM. MomenN.C. MonastaL. MondelloS. MooneyM.D. MoosazadehM. MoradiG. MoradiM. Moradi-LakehM. MoradzadehR. MoragaP. MoralesL. MorawskaL. Moreno VelásquezI. Morgado-da-CostaJ. MorrisonS.D. MosserJ.F. MouodiS. MousaviS.M. Mousavi KhaneghahA. MuellerU.O. MunroS.B. MuriithiM.K. MusaK.I. MuthupandianS. NaderiM. NagarajanA.J. NagelG. NaghshtabriziB. NairS. NandiA.K. NangiaV. NansseuJ.R. NayakV.C. NazariJ. NegoiI. NegoiR.I. NetsereH.B.N. NgunjiriJ.W. NguyenC.T. NguyenJ. NguyenM. NguyenM. NicholsE. NigatuD. NigatuY.T. NikbakhshR. NixonM.R. NnajiC.A. NomuraS. NorrvingB. NoubiapJ.J. NowakC. Nunez-SamudioV. OţoiuA. OanceaB. OdellC.M. OgboF.A. OhI-H. OkungaE.W. OladnabiM. OlagunjuA.T. OlusanyaB.O. OlusanyaJ.O. OluwasanuM.M. Omar BaliA. OmerM.O. OngK.L. OnwujekweO.E. OrjiA.U. OrpanaH.M. OrtizA. OstroffS.M. OtstavnovN. OtstavnovS.S. ØverlandS. OwolabiM.O. P AM. PadubidriJ.R. PakhareA.P. PalladinoR. PanaA. Panda-JonasS. PandeyA. ParkE-K. ParmarP.G.K. PasupulaD.K. PatelS.K. Paternina-CaicedoA.J. PathakA. PathakM. PattenS.B. PattonG.C. PaudelD. Pazoki ToroudiH. PedenA.E. PenniniA. PepitoV.C.F. PeprahE.K. PereiraA. PereiraD.M. PericoN. PhamH.Q. PhillipsM.R. PigottD.M. PilgrimT. PilzT.M. PirsahebM. Plana-RipollO. PlassD. PokhrelK.N. PolibinR.V. PolinderS. PolkinghorneK.R. PostmaM.J. PourjafarH. PourmalekF. Pourmirza KalhoriR. PourshamsA. PoznańskaA. PradaS.I. PrakashV. PribadiD.R.A. PupilloE. Quazi SyedZ. RabieeM. RabieeN. RadfarA. RafieeA. RafieiA. RaggiA. Rahimi-MovagharA. RahmanM.A. Rajabpour-SanatiA. RajatiF. RamezanzadehK. RanabhatC.L. RaoP.C. RaoS.J. RasellaD. RastogiP. RathiP. RawafD.L. RawafS. RawalL. RazoC. RedfordS.B. ReinerR.C.Jr ReinigN. ReitsmaM.B. RemuzziG. RenjithV. RenzahoA.M.N. ResnikoffS. RezaeiN. RezaiM. RezapourA. RhinehartP-A. RiahiS.M. RibeiroA.L.P. RibeiroD.C. RibeiroD. RickardJ. RobertsN.L.S. RobertsS. RobinsonS.R. RoeverL. RolfeS. RonfaniL. RoshandelG. RothG.A. RubagottiE. RumishaS.F. SabourS. SachdevP.S. SaddikB. SadeghiE. SadeghiM. SaeidiS. SafiS. SafiriS. SagarR. SahebkarA. SahraianM.A. SajadiS.M. SalahshoorM.R. SalamatiP. Salehi ZahabiS. SalemH. SalemM.R.R. SalimzadehH. SalomonJ.A. SalzI. SamadZ. SamyA.M. SanabriaJ. SantomauroD.F. SantosI.S. SantosJ.V. Santric-MilicevicM.M. SaraswathyS.Y.I. Sarmiento-SuárezR. SarrafzadeganN. SartoriusB. SarveazadA. SathianB. SathishT. SattinD. SbarraA.N. SchaefferL.E. SchiavolinS. SchmidtM.I. SchutteA.E. SchwebelD.C. SchwendickeF. SenbetaA.M. SenthilkumaranS. SepanlouS.G. ShackelfordK.A. ShadidJ. ShahabiS. ShaheenA.A. ShaikhM.A. ShalashA.S. Shams-BeyranvandM. ShamsizadehM. ShannawazM. SharafiK. ShararaF. SheenaB.S. SheikhtaheriA. ShettyR.S. ShibuyaK. ShiferawW.S. ShigematsuM. ShinJ.I. ShiriR. ShirkoohiR. ShrimeM.G. ShuvalK. SiabaniS. SigfusdottirI.D. SigurvinsdottirR. SilvaJ.P. SimpsonK.E. SinghA. SinghJ.A. SkiadaresiE. SkouS.T. SkryabinV.Y. SobngwiE. SokhanA. SoltaniS. SorensenR.J.D. SorianoJ.B. SorrieM.B. SoyiriI.N. SreeramareddyC.T. StanawayJ.D. StarkB.A. ŞtefanS.C. SteinC. SteinerC. SteinerT.J. StokesM.A. StovnerL.J. StubbsJ.L. SudaryantoA. SufiyanM.B. SuloG. SultanI. SykesB.L. SylteD.O. SzócskaM. Tabarés-SeisdedosR. TabbK.M. TadakamadlaS.K. TaherkhaniA. TajdiniM. TakahashiK. TaveiraN. TeagleW.L. TeameH. Tehrani-BanihashemiA. TeklehaimanotB.F. TerrasonS. TessemaZ.T. ThankappanK.R. ThomsonA.M. TohidinikH.R. TonelliM. Topor-MadryR. TorreA.E. TouvierM. Tovani-PaloneM.R.R. TranB.X. TravillianR. TroegerC.E. TruelsenT.C. TsaiA.C. TsatsakisA. Tudor CarL. TyrovolasS. UddinR. UllahS. UndurragaE.A. UnnikrishnanB. VacanteM. VakilianA. ValdezP.R. VarugheseS. VasankariT.J. VasseghianY. VenketasubramanianN. ViolanteF.S. VlassovV. VollsetS.E. VongpradithA. VukovicA. VukovicR. WaheedY. WaltersM.K. WangJ. WangY. WangY-P. WardJ.L. WatsonA. WeiJ. WeintraubR.G. WeissD.J. WeissJ. WestermanR. WhisnantJ.L. WhitefordH.A. WiangkhamT. WiensK.E. WijeratneT. WilnerL.B. WilsonS. WojtyniakB. WolfeC.D.A. WoolE.E. WuA-M. Wulf HansonS. WunrowH.Y. XuG. XuR. YadgirS. Yahyazadeh JabbariS.H. YamagishiK. YaminfiroozM. YanoY. YayaS. Yazdi-FeyzabadiV. YearwoodJ.A. YeheyisT.Y. YeshitilaY.G. YipP. YonemotoN. YoonS-J. Yoosefi LebniJ. YounisM.Z. YounkerT.P. YousefiZ. YousefifardM. YousefinezhadiT. YousufA.Y. YuC. YusefzadehH. Zahirian MoghadamT. ZakiL. ZamanS.B. ZamaniM. ZamanianM. ZandianH. ZangenehA. ZastrozhinM.S. ZewdieK.A. ZhangY. ZhangZ-J. ZhaoJ.T. ZhaoY. ZhengP. ZhouM. ZiapourA. ZimsenS.R.M. NaghaviM. MurrayC.J.L. GBD 2019 Diseases and Injuries Collaborators Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019.Lancet2020396102581204122210.1016/S0140‑6736(20)30925‑933069326
     [Google Scholar]
  7. KiharaS. [Dyslipidemia].Jpn. J. Clin. Med.201371227527910.7326/AITC20171205023631206
     [Google Scholar]
  8. LintonMF YanceyPG DaviesSS JeromeWG LintonEF SongWL The role of lipids and lipoproteins in atherosclerosis.Science (80-)2019111166186
     [Google Scholar]
  9. MulitaF LampropoulosC KehagiasD VerrasG-I TchabashviliL KaplanisC Long-term nutritional deficiencies following sleeve gastrectomy: A 6-year single-centre retrospective study.Menopause Rev20212017017610.5114/pm.2021.110954
     [Google Scholar]
  10. QiL. GuoY. LiuC.Q. HuangZ.P. ShengY. ZouD.J. Effects of bariatric surgery on glycemic and lipid metabolism, surgical complication and quality of life in adolescents with obesity: A systematic review and meta-analysis.Surg. Obes. Relat. Dis.201713122037205510.1016/j.soard.2017.09.51629079384
     [Google Scholar]
  11. LiuD. MaZ. ZhangC. LinQ. LiM. SuK. LiY. WangH. ZangQ. DongJ. The effects of bariatric surgery on dyslipidemia and insulin resistance in overweight patients with or without type 2 diabetes: A systematic review and network meta-analysis.Surg. Obes. Relat. Dis.20211791655167210.1016/j.soard.2021.04.00534229937
     [Google Scholar]
  12. AthyrosV.G. StavropoulosK. ImprialosK.P. DoumasM. Suboptimal management of dyslipidemia in everyday clinical practice: Alarming signals from real-world data.Int. J. Cardiol.202031624024110.1016/j.ijcard.2020.06.05932634493
     [Google Scholar]
  13. AliH.I. ElmiF. StojanovskaL. IbrahimN. Cheikh IsmailL. Al DhaheriA.S. Associations of dyslipidemia with dietary intakes, body weight status and sociodemographic factors among adults in the United Arab Emirates.Nutrients20221416340510.3390/nu1416340536014911
     [Google Scholar]
  14. PirilloA. CasulaM. OlmastroniE. NorataG.D. CatapanoA.L. Global epidemiology of dyslipidaemias.Nat. Rev. Cardiol.2021181068970010.1038/s41569‑021‑00541‑433833450
     [Google Scholar]
  15. Al RasadiK. AlmahmeedW. AlHabibK.F. AbifadelM. FarhanH.A. AlSifriS. JambartS. ZubaidM. AwanZ. Al-WailiK. BarterP. Dyslipidaemia in the Middle East: Current status and a call for action.Atherosclerosis201625218218710.1016/j.atherosclerosis.2016.07.92527522462
     [Google Scholar]
  16. TaddeiC. ZhouB. BixbyH. Carrillo-LarcoR.M. DanaeiG. JacksonR.T. FarzadfarF. SophieaM.K. Di CesareM. IurilliM.L.C. MartinezA.R. AsghariG. DhanaK. GulayinP. KakarmathS. SanteroM. VoortmanT. RileyL.M. CowanM.J. SavinS. BennettJ.E. StevensG.A. PaciorekC.J. AekplakornW. CifkovaR. GiampaoliS. KengneA.P. KhangY-H. KuulasmaaK. LaxmaiahA. MargozziniP. MathurP. NordestgaardB.G. ZhaoD. AadahlM. Abarca-GómezL. RahimH.A. Abu-RmeilehN.M. Acosta-CazaresB. AdamsR.J. AgdeppaI.A. Aghazadeh-AttariJ. Aguilar-SalinasC.A. AgyemangC. AhluwaliaT.S. AhmadN.A. AhmadiA. AhmadiN. AhmedS.H. AhrensW. AjlouniK. AlaroujM. AlBuhairanF. AlDhukairS. AliM.M. AlkandariA. AlkerwiA. AlyE. AmarapurkarD.N. AmouyelP. AndersenL.B. AnderssenS.A. AnjanaR.M. Ansari-MoghaddamA. Aounallah-SkhiriH. AraújoJ. AriansenI. ArisT. ArkuR.E. ArlappaN. AryalK.K. AspelundT. AssunçãoM.C.F. AuvinenJ. AvdicováM. AzevedoA. AziziF. AzminM. BalakrishnaN. BamoshmooshM. BanachM. BandoszP. BanegasJ.R. BarbagalloC.M. BarcelóA. BarkatA. BataI. BatiehaA.M. BatyrbekA. BaurL.A. BeagleholeR. BelavendraA. Ben RomdhaneH. BenetM. BennM. BerkinbayevS. Bernabe-OrtizA. BernotieneG. BettiolH. BhargavaS.K. BiY. BienekA. BikbovM. BistaB. BjerregaardP. BjertnessE. BjertnessM.B. BjörkelundC. BlochK.V. BlokstraA. BoS. BoehmB.O. BoggiaJ.G. BoissonnetC.P. BonaccioM. BongardV. BorchiniR. BorghsH. BovetP. BrajkovichI. BreckenkampJ. BrennerH. BrewsterL.M. BrunoG. BuggeA. BuschM.A. de LeónA.C. CacciottoloJ. CanG. CândidoA.P.C. CapanzanaM.V. CapuanoE. CapuanoV. CardosoV.C. CarvalhoJ. CasanuevaF.F. CensiL. ChadjigeorgiouC.A. ChamukuttanS. ChaturvediN. ChenC-J. ChenF. ChenS. ChengC-Y. CheraghianB. ChetritA. ChiouS-T. ChirlaqueM-D. ChoB. ChoY. ChudekJ. ClaessensF. ClarkeJ. ClaysE. ConcinH. ConfortinS.C. CooperC. CostanzoS. CottelD. CowellC. CrujeirasA.B. CsillaS. CuiL. CureauF.V. D’ArrigoG. d’OrsiE. DallongevilleJ. DamascenoA. DanknerR. DantoftT.M. DauchetL. DavletovK. De BackerG. De BacquerD. de GaetanoG. De HenauwS. de OliveiraP.D. De RidderD. De SmedtD. DeepaM. DeevA.D. DehghanA. DelisleH. DennisonE. DeschampsV. DhimalM. Di CastelnuovoA.F. DikaZ. DjalaliniaS. DobsonA.J. DonfrancescoC. DonosoS.P. DöringA. DorobantuM. DraganoN. DrygasW. DuY. DuanteC.A. DudaR.B. DzerveV. Dziankowska-ZaborszczykE. EddieR. EftekharE. EggertsenR. EghtesadS. EibenG. EkelundU. El AtiJ. Eldemire-ShearerD. EliasenM. ElosuaR. ErasmusR.T. ErbelR. EremC. EriksenL. ErikssonJ.G. Escobedo-de la PeñaJ. EslamiS. EsmaeiliA. EvansA. FaehD. FallC.H. FaramarziE. FarjamM. FattahiM.R. Felix-RedondoF.J. FergusonT.S. Fernández-BergésD. FerranteD. FerrariM. FerreccioC. FerrieresJ. FögerB. FooL.H. ForslundA-S. ForsnerM. FouadH.M. FrancisD.K. do Carmo FrancoM. FrancoO.H. FronteraG. FujitaY. FumihikoM. FurusawaT. GaciongZ. GalvanoF. GaoJ. Garcia-de-la-HeraM. GarnettS.P. GaspozJ-M. GasullM. GazzinelliA. GeleijnseJ.M. GhanbariA. GhasemiE. Gheorghe-FroneaO-F. GhimireA. GianfagnaF. GillT.K. GiovannelliJ. GironellaG. GiwercmanA. GoltzmanD. GonçalvesH. Gonzalez-ChicaD.A. Gonzalez-GrossM. González-RivasJ.P. González-VillalpandoC. González-VillalpandoM-E. GonzalezA.R. GottrandF. Graff-IversenS. GrafnetterD. GregorR.D. GrodzickiT. GrøntvedA. GrossoG. GrudenG. GuD. Guallar-CastillónP. GuanO.P. GudmundssonE.F. GudnasonV. GuerreroR. GuessousI. GunnlaugsdottirJ. GuptaR. GutierrezL. GutzwillerF. HaS. HadaeghF. HaghshenasR. HakimiH. HambletonI.R. HamzehB. HantunenS. KumarR.H. Hashemi-ShahriS.M. HataJ. HaugsgjerdT. HayesA.J. HeJ. HeY. HendriksM.E. HenriquesA. HerralaS. HeshmatR. HillA.G. HoS.Y. HoS.C. HobbsM. HofmanA. HomayounfarR. HopmanW.M. HorimotoA.R.V.R. HormigaC.M. HortaB.L. HoutiL. HowittC. HtayT.T. HtetA.S. HtikeM.M.T. HuertaJ.M. HuhtaniemiI.T. HuismanM. HunsbergerM.L. HusseiniA.S. HuybrechtsI. HwallaN. IacovielloL. IannoneA.G. IbrahimM.M. WongN.I. IglesiaI. IkedaN. IkramM.A. IotovaV. IrazolaV.E. IshidaT. IslamM. al-Safi IsmailA. IwasakiM. JacobsJ.M. JaddouH.Y. JafarT. JamesK. JamrozikK. JanszkyI. JanusE. JarvelinM-R. JasienskaG. JelakovicA. JelakovicB. JenningsG. JensenG.B. JeongS. JhaA.K. JiangC.Q. JimenezR.O. JöckelK-H. JoffresM. JokelainenJ.J. JonasJ.B. JørgensenT. JoshiP. JoukarF. JózwiakJ. JuoleviA. KafatosA. KajantieE.O. Kalter-LeiboviciO. KamaruddinN.A. KamstrupP.R. KarkiK.B. KatzJ. KauhanenJ. KaurP. KavousiM. KazakbaevaG. KeilU. Keinänen-KiukaanniemiS. KelishadiR. KeramatiM. KerimkulovaA. KerstingM. KhaderY.S. KhaliliD. KhateebM. KheradmandM. KhosraviA. Kiechl-KohlendorferU. KiechlS. KillewoJ. KimH.C. KimJ. KimY-Y. KlumbieneJ. KnoflachM. KoS. KohlerH-P. KohlerI.V. KolleE. KolsterenP. KönigJ. KorpelainenR. KorrovitsP. KosJ. KoskinenS. KoudaK. KowlessurS. KratzerW. KriemlerS. KristensenP.L. KrokstadS. KromhoutD. KujalaU.M. KurjataP. KyobutungiC. LaamiriF.Z. LaatikainenT. LachatC. LaidY. LamT.H. LambrinouC-P. LanskaV. LappasG. LarijaniB. LattT.S. LaugsandL.E. Lazo-PorrasM. LeeJ. LeeJ. LehmannN. LehtimäkiT. LevittN.S. LiY. LillyC.L. LimW-Y. Lima-CostaM.F. LinH-H. LinX. LinY-T. LindL. LinnebergA. LissnerL. LiuJ. LoitH-M. Lopez-GarciaE. LopezT. LotufoP.A. LozanoJ.E. LuksieneD. LundqvistA. LundqvistR. LunetN. MaG. Machado-CoelhoG.L.L. Machado-RodriguesA.M. MachiS. MadarA.A. MaggiS. MaglianoD.J. MagriplisE. MahasampathG. MaireB. MakdisseM. MalekzadehF. MalekzadehR. RaoK.M. ManiosY. MannJ.I. Mansour-GhanaeiF. ManzatoE. Marques-VidalP. MartorellR. MascarenhasL.P. MathiesenE.B. MatshaT.E. MavrogianniC. McFarlaneS.R. McGarveyS.T. McLachlanS. McLeanR.M. McLeanS.B. McNultyB.A. Mediene-BenchekorS. MehdipourP. MehligK. MehrparvarA.H. MeirhaegheA. MeisingerC. MenezesA.M.B. MenonG.R. MeratS. MerekeA. MeshramI.I. MetcalfP. MeyerH.E. MiJ. MichelsN. MillerJ.C. MindericoC.S. MiniG.K. MiquelJ.F. MirandaJ.J. MirjaliliM.R. MirrakhimovE. ModestiP.A. MoghaddamS.S. MohajerB. MohamedM.K. MohammadK. MohammadiZ. MohammadifardN. MohammadpourhodkiR. MohanV. MohannaS. YusoffM.F.M. MohebbiI. MohebiF. MoitryM. MøllehaveL.T. MøllerN.C. MolnárD. MomenanA. MondoC.K. Monterrubio-FloresE. MoosazadehM. MorejonA. MorenoL.A. MorganK. MorinS.N. MoschonisG. MossakowskaM. MostafaA. MotaJ. MotlaghM.E. MottaJ. MsyambozaK.P. MuiesanM.L. Müller-NurasyidM. MursuJ. MustafaN. NabipourI. NaderimaghamS. NagelG. NaiduB.M. NajafiF. NakamuraH. NámešnáJ. NangE.E.K. NangiaV.B. NauckM. NealW.A. NejatizadehA. NenkoI. NerviF. NguyenN.D. NguyenQ.N. Nieto-MartínezR.E. NihalT. NiiranenT.J. NingG. NinomiyaT. NoaleM. NoboaO.A. NotoD. NsourM.A. NuhoğluI. O’NeillT.W. O’ReillyD. Ochoa-AvilésA.M. OhK. OhtsukaR. OlafssonÖ. OliéV. OliveiraI.O. OmarM.A. OnatA. OngS.K. OrdunezP. OrnelasR. OrtizP.J. OsmondC. OstojicS.M. OstovarA. OteroJ.A. Owusu-DaboE. PaccaudF.M. PahomovaE. PajakA. PalmieriL. PanW-H. Panda-JonasS. PanzaF. ParnellW.R. PatelN.D. PeerN. PeixotoS.V. PeltonenM. PereiraA.C. PetersA. PetersmannA. PetkevicieneJ. PeykariN. PhamS.T. PichardoR.N. PigeotI. PilavA. PilottoL. PiwonskaA. PizarroA.N. Plans-RubióP. PlataS. PohlabelnH. PortaM. PortegiesM.L.P. PoudyalA. PourfarziF. PoustchiH. PradeepaR. PriceJ.F. ProvidenciaR. PuderJ.J. PuhakkaS.E. PunabM. QorbaniM. BaoT.Q. RadisauskasR. RahimikazerooniS. RaitakariO. RaoS.R. RamachandranA. RamosE. RamosR. RampalL. RampalS. RedonJ. ReganitP.F.M. RevillaL. RezaianzadehA. RibeiroR. RichterA. RigoF. Rinke de WitT.F. Rodríguez-ArtalejoF. del Cristo Rodriguez-PerezM. Rodríguez-VillamizarL.A. RoggenbuckU. Rojas-MartinezR. RomagueraD. RomeoE.L. RosengrenA. RoyJ.G.R. RubinsteinA. RuidavetsJ-B. Ruiz-BetancourtB.S. RussoP. RustP. RutkowskiM. SabanayagamC. SachdevH.S. SadjadiA. SafarpourA.R. SafiriS. SaidiO. SakiN. SalanaveB. SalmerónD. SalomaaV. SalonenJ.T. SalvettiM. Sánchez-AbantoJ. SansS. Santaliestra-PasíasA.M. SantosD.A. SantosM.P. SantosR. SaramiesJ.L. SardinhaL.B. SarrafzadeganN. SaumK-U. SavvaS.C. SawadaN. SbarainiM. ScazufcaM. SchaanB.D. SchargrodskyH. Scheidt-NaveC. SchienkiewitzA. SchipfS. SchmidtC.O. SchöttkerB. SchrammS. SebertS. SeinA.A. SenA. SepanlouS.G. ServaisJ. ShakeriR. ShalnovaS.A. Shamah-LevyT. SharafkhahM. SharmaS.K. ShawJ.E. ShayanradA. ShiZ. ShibuyaK. Shimizu-FurusawaH. ShinD.W. ShinY. ShiraniM. ShiriR. ShresthaN. Si-RamleeK. SianiA. SiantarR. SibaiA.M. SilvaD.A.S. SimonM. SimonsJ. SimonsL.A. SjöströmM. SkaabyT. Slowikowska-HilczerJ. SlusarczykP. SmeethL. SnijderM.B. SöderbergS. SoemantriA. SofatR. SolfrizziV. SomiM.H. SonestedtE. SørensenT.I.A. JéromeC.S. SoumaréA. SozmenK. SparrenbergerK. StaessenJ.A. StathopoulouM.G. StavreskiB. Steene-JohannessenJ. StehleP. SteinA.D. StessmanJ. StevanovićR. StieberJ. StöcklD. StokwiszewskiJ. StronksK. StrufaldiM.W. Suárez-MedinaR. SunC-A. SundströmJ. SuriyawongpaisalP. SyR.G. SylvaR.C. SzkloM. TaiE.S. TamosiunasA. TanE.J. TarawnehM.R. Tarqui-MamaniC.B. TaylorA. TaylorJ. TellG.S. TelloT. ThankappanK.R. ThijsL. ThuesenB.H. ToftU. TolonenH.K. TolstrupJ.S. TopbasM. Topór-MadryR. TormoM.J. TornaritisM.J. TorrentM. Torres-ColladoL. TraissacP. TrinhO.T.H. TruthmannJ. TsuganeS. Tulloch-ReidM.K. TuomainenT-P. TuomilehtoJ. Tybjaerg-HansenA. TzourioC. UedaP. UgelE. UlmerH. UnalB. UusitaloH.M.T. ValdiviaG. ValviD. van DamR.M. van der SchouwY.T. Van HerckK. Van MinhH. van RossemL. Van SchoorN.M. van ValkengoedI.G.M. VanderschuerenD. VanuzzoD. VarboA. Varona-PérezP. VasanS.K. VattenL. VegaT. VeidebaumT. Velasquez-MelendezG. Venero-FernándezS.J. VeronesiG. VerschurenW.M.M. VictoraC.G. VidiawatiD. VietL. VillalpandoS. VioqueJ. VirtanenJ.K. Visvikis-SiestS. ViswanathanB. VlasoffT. VollenweiderP. VoutilainenA. WadeA.N. WagnerA. WaltonJ. BebakarW.M.W. MohamudW.N.W. WangM-D. WangN. WangQ. WangY.X. WangY-W. WannametheeS.G. WedderkoppN. WeiW. WhincupP.H. WidhalmK. WidyaheningI.S. WiecekA. WijgaA.H. WilksR.J. WilleitJ. WilleitP. WilsgaardT. WojtyniakB. Wong-McClureR.A. WongA. WongT.Y. WooJ. WoodwardM. WuF.C. WuS. XuH. XuL. YanW. YangX. YasuharuT. YeX. YeowT.P. YiallourosP.K. YoosefiM. YoshiharaA. YouS-L. Younger-ColemanN.O. YusoffA.F. ZainuddinA.A. ZakaviS.R. ZaliM.R. ZamaniF. ZambonS. ZampelasA. ZawK.K. ZdrojewskiT. VrkicT.Z. ZhangZ-Y. ZhaoW. ZhenS. ZhengY. ZholdinB. ZhussupovB. ZoghlamiN. CisnerosJ.Z. GreggE.W. EzzatiM. NCD Risk Factor Collaboration (NCD-RisC) Repositioning of the global epicentre of non-optimal cholesterol.Nature20205827810737710.1038/s41586‑020‑2338‑132494083
     [Google Scholar]
  17. MahmoudI. SulaimanN. Prevalence of metabolic syndrome and associated risk factors in the United Arab Emirates: A cross-sectional population-based study.Front. Public Health2022981100610.3389/fpubh.2021.81100635141192
     [Google Scholar]
  18. Al MahmeedW. BakirS. BeshyahS. MorcosB. WajihS. HorackM. LautschD. AmbegaonkarB. BrudiP. BaxterC. VyasA. GittA. Prevalence of lipid abnormalities and cholesterol target value attainment in patients with stable and acute coronary heart disease in the United Arab Emirates.Heart Views2019202374610.4103/HEARTVIEWS.HEARTVIEWS_32_1831462957
     [Google Scholar]
  19. Al-RasadiK. AlhabibK.F. Al-AllafF. Al-WailiK. Al-ZakwaniI. AlSarrafA. AlmahmeedW. AlSayedN. AlghamdiM. BataisM.A. AlmigbalT.H. AlnouriF. KinsaraA. HammoudaA. AwanZ. KaryH. ElaminO.A. ZadjaliF. Al-JarallahM. ShehabA. SabbourH. AminH. AltaradiH. The gulf familial hypercholesterolemia registry (Gulf FH): Design, rationale and preliminary results.Curr. Vasc. Pharmacol.2019181576410.2174/157016111666618100512545930289081
     [Google Scholar]
  20. NelsonA.J. RochelauS.K. NichollsS.J. Managing dyslipidemia in type 2 diabetes.Endocrinol. Metab. Clin. North Am.201847115317310.1016/j.ecl.2017.10.00429407049
     [Google Scholar]
  21. GazzazZ.J. IftikharR. JameelT. BaigM. MuradM.A. Association of dyslipidemia and comorbidities with risk factors among diabetic patients: A retrospective analysis.Diabetes Metab. Syndr. Obes.20201393594110.2147/DMSO.S23554632280252
     [Google Scholar]
  22. ShahwanM.J. JairounA.A. FarajallahA. ShanabliS. Prevalence of dyslipidemia and factors affecting lipid profile in patients with type 2 diabetes.Diabetes Metab. Syndr.20191342387239210.1016/j.dsx.2019.06.00931405648
     [Google Scholar]
  23. MachF. BaigentC. CatapanoA.L. KoskinasK.C. CasulaM. BadimonL. ChapmanM.J. De BackerG.G. DelgadoV. FerenceB.A. GrahamI.M. HallidayA. LandmesserU. MihaylovaB. PedersenT.R. RiccardiG. RichterD.J. SabatineM.S. TaskinenM.R. TokgozogluL. WiklundO. MuellerC. DrexelH. AboyansV. CorsiniA. DoehnerW. FarnierM. GiganteB. KayikciogluM. KrstacicG. LambrinouE. LewisB.S. MasipJ. MoulinP. PetersenS. PetronioA.S. PiepoliM.F. PintóX. RäberL. RayK.K. ReinerŽ. RiesenW.F. RoffiM. SchmidJ-P. ShlyakhtoE. SimpsonI.A. StroesE. SudanoI. TselepisA.D. ViigimaaM. VindisC. VonbankA. VrablikM. VrsalovicM. ZamoranoJ.L. ColletJ-P. KoskinasK.C. CasulaM. BadimonL. John ChapmanM. De BackerG.G. DelgadoV. FerenceB.A. GrahamI.M. HallidayA. LandmesserU. MihaylovaB. PedersenT.R. RiccardiG. RichterD.J. SabatineM.S. TaskinenM-R. TokgozogluL. WiklundO. WindeckerS. AboyansV. BaigentC. ColletJ-P. DeanV. DelgadoV. FitzsimonsD. GaleC.P. GrobbeeD. HalvorsenS. HindricksG. IungB. JüniP. KatusH.A. LandmesserU. LeclercqC. LettinoM. LewisB.S. MerkelyB. MuellerC. PetersenS. PetronioA.S. RichterD.J. RoffiM. ShlyakhtoE. SimpsonI.A. Sousa-UvaM. TouyzR.M. NiboucheD. ZelveianP.H. SiostrzonekP. NajafovR. van de BorneP. PojskicB. PostadzhiyanA. KyprisL. ŠpinarJ. LarsenM.L. EldinH.S. ViigimaaM. StrandbergT.E. FerrièresJ. AgladzeR. LaufsU. RallidisL. BajnokL. GudjónssonT. MaherV. HenkinY. GuliziaM.M. MussagaliyevaA. BajraktariG. KerimkulovaA. LatkovskisG. HamouiO. SlapikasR. VisserL. DingliP. IvanovV. BoskovicA. NazziM. VisserenF. MitevskaI. RetterstølK. JankowskiP. Fontes-CarvalhoR. GaitaD. EzhovM. FoscoliM. GigaV. PellaD. FrasZ. de IslaL.P. HagströmE. LehmannR. AbidL. OzdoganO. MitchenkoO. PatelR.S. ESC Scientific Document Group 2019 ESC/EAS Guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk.Eur. Heart J.202041111118810.1093/eurheartj/ehz45531504418
     [Google Scholar]
  24. JinJ. Lipid disorders: Screening and treatment.JAMA2016316192056205610.1001/jama.2016.1665027838718
     [Google Scholar]
  25. JellingerP.S. HandelsmanY. RosenblitP.D. BloomgardenZ.T. FonsecaV.A. GarberA.J. GrunbergerG. GuerinC.K. BellD.S.H. MechanickJ.I. Pessah-PollackR. WyneK. SmithD. BrintonE.A. FazioS. DavidsonM. JellingerP.S. HandelsmanY. BellD.S.H. BloomgardenZ.T. BrintonE.A. DavidsonM.H. FazioS. FonsecaV.A. GarberA.J. GrunbergerG. GuerinC.K. MechanickJ.I. Pessah-PollackR. RosenblitP.D. SmithD.A. WyneK. BushM. ZangenehF. HandelsmanY. BellD.S.H. BloomgardenZ.T. BrintonE.A. FazioS. FonsecaV.A. GarberA.J. GrunbergerG. GuerinC.K. JellingerP.S. RosenblitP.D. SmithD.A. WyneK. DavidsonM.H. American association of clinical endocrinologists and american college of endocrinology guidelines for management of dyslipidemia and prevention of cardiovascular disease.Endocr. Pract.201723Suppl. 218710.4158/EP171764.APPGL28437620
     [Google Scholar]
  26. AmirA. AlasnagM. Al-RaddadiR. Al-BassamT. SaeedK. YazıcıoğluM. ShabanaA. Patient journey for hypertension and dyslipidemia in Saudi Arabia: Highlighting the evidence gaps.Arch. Public Health202381112210.1186/s13690‑023‑01121‑337400868
     [Google Scholar]
  27. Di AngelantonioE. GaoP. PennellsL. KaptogeS. CaslakeM. ThompsonA. ButterworthA.S. SarwarN. WormserD. SaleheenD. BallantyneC.M. PsatyB.M. SundströmJ. RidkerP.M. NagelD. GillumR.F. FordI. DucimetiereP. KiechlS. KoenigW. DullaartR.P. AssmannG. D’AgostinoR.B.Sr DagenaisG.R. CooperJ.A. KromhoutD. OnatA. TippingR.W. Gómez-de-la-CámaraA. RosengrenA. SutherlandS.E. GallacherJ. FowkesF.G. CasigliaE. HofmanA. SalomaaV. Barrett-ConnorE. ClarkeR. BrunnerE. JukemaJ.W. SimonsL.A. SandhuM. WarehamN.J. KhawK.T. KauhanenJ. SalonenJ.T. HowardW.J. NordestgaardB.G. WoodA.M. ThompsonS.G. BoekholdtS.M. SattarN. PackardC. GudnasonV. DaneshJ. Emerging Risk Factors Collaboration Lipid-related markers and cardiovascular disease prediction.JAMA2012307232499250610.1001/jama.2012.657122797450
     [Google Scholar]
  28. BaigentC. BlackwellL. EmbersonJ. HollandL.E. ReithC. BhalaN. PetoR. BarnesE.H. KeechA. SimesJ. CollinsR. Cholesterol Treatment Trialists’ (CTT) Collaboration Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170 000 participants in 26 randomised trials.Lancet201037697531670168110.1016/S0140‑6736(10)61350‑521067804
     [Google Scholar]
  29. SathiyakumarV. ParkJ. GolozarA. LazoM. QuispeR. GuallarE. BlumenthalR.S. JonesS.R. MartinS.S. Fasting versus nonfasting and low-density lipoprotein cholesterol accuracy.Circulation20181371101910.1161/CIRCULATIONAHA.117.03067729038168
     [Google Scholar]
  30. MachF. BaigentC. CatapanoA.L. KoskinasK.C. CasulaM. BadimonL. ChapmanM.J. De BackerG.G. DelgadoV. FerenceB.A. GrahamI.M. HallidayA. LandmesserU. MihaylovaB. PedersenT.R. RiccardiG. RichterD.J. SabatineM.S. TaskinenM-R. TokgozogluL. WiklundO. WindeckerS. AboyansV. BaigentC. ColletJ-P. DeanV. DelgadoV. FitzsimonsD. GaleC.P. GrobbeeD. HalvorsenS. HindricksG. IungB. JüniP. KatusH.A. LandmesserU. LeclercqC. LettinoM. LewisB.S. MerkelyB. MuellerC. PetersenS. PetronioA.S. RichterD.J. RoffiM. ShlyakhtoE. SimpsonI.A. Sousa-UvaM. TouyzR.M. NiboucheD. ZelveianP.H. SiostrzonekP. NajafovR. van de BorneP. PojskicB. PostadzhiyanA. KyprisL. ŠpinarJ. LarsenM.L. EldinH.S. ViigimaaM. StrandbergT.E. FerrièresJ. AgladzeR. LaufsU. RallidisL. BajnokL. GudjónssonT. MaherV. HenkinY. GuliziaM.M. MussagaliyevaA. BajraktariG. KerimkulovaA. LatkovskisG. HamouiO. SlapikasR. VisserL. DingliP. IvanovV. BoskovicA. NazziM. VisserenF. MitevskaI. RetterstølK. JankowskiP. Fontes-CarvalhoR. GaitaD. EzhovM. FoscoliM. GigaV. PellaD. FrasZ. Perez de IslaL. HagströmE. LehmannR. AbidL. OzdoganO. MitchenkoO. PatelR.S. Authors/Task Force Members ESC Committee for Practice Guidelines (CPG) ESC National Cardiac Societies 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk.Atherosclerosis201929014020510.1016/j.atherosclerosis.2019.08.01431591002
     [Google Scholar]
  31. PiepoliM.F. HoesA.W. AgewallS. AlbusC. BrotonsC. CatapanoA.L. CooneyM-T. CorràU. CosynsB. DeatonC. GrahamI. HallM.S. HobbsF.D.R. LøchenM-L. LöllgenH. Marques-VidalP. PerkJ. PrescottE. RedonJ. RichterD.J. SattarN. SmuldersY. TiberiM. van der WorpH.B. van DisI. VerschurenW.M.M. 2016 European Guidelines on cardiovascular disease prevention in clinical practice.Eur. Heart J.201637292315238110.1093/eurheartj/ehw10627222591
     [Google Scholar]
  32. OzenG. SunbulM. AtagunduzP. DireskeneliH. TigenK. InancN. The 2013 ACC/AHA 10-year atherosclerotic cardiovascular disease risk index is better than SCORE and QRisk II in rheumatoid arthritis: Is it enough?Rheumatology2015553kev36310.1093/rheumatology/kev36326472565
     [Google Scholar]
  33. Hippisley-CoxJ. CouplandC. VinogradovaY. RobsonJ. MinhasR. SheikhA. BrindleP. Predicting cardiovascular risk in England and Wales: Prospective derivation and validation of QRISK2.BMJ200833676591475148210.1136/bmj.39609.449676.2518573856
     [Google Scholar]
  34. EllahhamS. Understanding the management of hypertension and dyslipidaemia in UAE population: An evidence-based mapping of literature.Saudi J. Med2021611367378
     [Google Scholar]
  35. Pedro-BotetJ. ClimentE. Giralt MartínezE. Flores-Le RouxJ.A. [Map of resources and healthcare needs for patients with dyslipidaemia in Spain: The MADI study].Clin. Investig. Arterioscler.201628625726410.1016/j.arteri.2016.06.00527692631
     [Google Scholar]
  36. AlhajjiS. MojiminiyiS. Adherence to current lipid guidelines by physicians in Kuwait.Med. Princ. Pract.202029543644310.1159/00050524431805555
     [Google Scholar]
  37. PearsonG.J. ThanassoulisG. AndersonT.J. BarryA.R. CoutureP. DayanN. FrancisG.A. GenestJ. GrégoireJ. GroverS.A. GuptaM. HegeleR.A. LauD. LeiterL.A. LeungA.A. LonnE. ManciniG.B.J. ManjooP. McPhersonR. NguiD. PichéM.E. PoirierP. SievenpiperJ. StoneJ. WardR. WrayW. 2021 canadian cardiovascular society guidelines for the management of dyslipidemia for the prevention of cardiovascular disease in adults.Can. J. Cardiol.20213781129115010.1016/j.cjca.2021.03.01633781847
     [Google Scholar]
  38. RheeE.J. KimH.C. KimJ.H. LeeE.Y. KimB.J. KimE.M. SongY. LimJ.H. KimH.J. ChoiS. MoonM.K. NaJ.O. ParkK.Y. OhM.S. HanS.Y. NohJ. YiK.H. LeeS.H. HongS.C. JeongI.K. Committee of Clinical Practice Guideline of Korean Society of Lipid and Atherosclerosis 2018 guidelines for the management of dyslipidemia in Korea.J. Lipid Atheroscler.2019827813110.12997/jla.2019.8.2.7832821702
     [Google Scholar]
  39. KinoshitaM. YokoteK. AraiH. IidaM. IshigakiY. IshibashiS. UmemotoS. EgusaG. OhmuraH. OkamuraT. KiharaS. KobaS. SaitoI. ShojiT. DaidaH. TsukamotoK. DeguchiJ. DohiS. DobashiK. HamaguchiH. HaraM. HiroT. BiroS. FujiokaY. MaruyamaC. MiyamotoY. MurakamiY. YokodeM. YoshidaH. RakugiH. WakatsukiA. YamashitaS. Japan atherosclerosis society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017.J. Atheroscler. Thromb.201825984698410.5551/jat.GL201730135334
     [Google Scholar]
  40. LiuT. ZhaoD. QiY. Global trends in the epidemiology and management of dyslipidemia.J. Clin. Med.20221121637710.3390/jcm1121637736362605
     [Google Scholar]
  41. SoranH. DentR. DurringtonP. Evidence-based goals in LDL-C reduction.Clin. Res. Cardiol.2017106423724810.1007/s00392‑016‑1069‑728124099
     [Google Scholar]
  42. VavlukisM. VavlukisA. Adding ezetimibe to statin therapy: Latest evidence and clinical implications.Drugs Context2018721253410.7573/dic.21253430023003
     [Google Scholar]
  43. WatersD.D. GuytonJ.R. HerringtonD.M. McGowanM.P. WengerN.K. ShearC. TNT Steering Committee Members and Investigators Treating to New Targets (TNT) Study: Does lowering low-density lipoprotein cholesterol levels below currently recommended guidelines yield incremental clinical benefit?Am. J. Cardiol.200493215415810.1016/j.amjcard.2003.09.03114715339
     [Google Scholar]
  44. RobinsonJ.G. RogersW.J. NedergaardB.S. FialkowJ. NeutelJ.M. RamstadD. SomaratneR. LeggJ.C. NelsonP. ScottR. WassermanS.M. WeissR. Rationale and design of LAPLACE-2: A phase 3, randomized, double-blind, placebo- and ezetimibe-controlled trial evaluating the efficacy and safety of evolocumab in subjects with hypercholesterolemia on background statin therapy.Clin. Cardiol.201437419520310.1002/clc.2225224481874
     [Google Scholar]
  45. HongS.J. JeongH.S. AhnJ.C. ChaD.H. WonK.H. KimW. ChoS.K. KimS.Y. YooB.S. SungK.C. RhaS.W. ShinJ.H. HanK.R. ChungW.S. HyonM.S. LeeH.C. BaeJ.H. RheeM.Y. KwanJ. JeonD.W. YooK.D. KimH.S. A phase III, multicenter, randomized, double-blind, active comparator clinical trial to compare the efficacy and safety of combination therapy with ezetimibe and rosuvastatin versus rosuvastatin monotherapy in patients with hypercholesterolemia: I-ROSETTE (ildong rosuvastatin & ezetimibe for hypercholesterolemia) randomized controlled trial.Clin. Ther.2018402226241.e410.1016/j.clinthera.2017.12.01829402522
     [Google Scholar]
  46. BohulaE.A. GiuglianoR.P. CannonC.P. ZhouJ. MurphyS.A. WhiteJ.A. TershakovecA.M. BlazingM.A. BraunwaldE. Achievement of dual low-density lipoprotein cholesterol and high-sensitivity C-reactive protein targets more frequent with the addition of ezetimibe to simvastatin and associated with better outcomes in IMPROVE-IT.Circulation2015132131224123310.1161/CIRCULATIONAHA.115.01838126330412
     [Google Scholar]
  47. BuchwaldH. VarcoR.L. MattsJ.P. LongJ.M. FitchL.L. CampbellG.S. PearceM.B. YellinA.E. EdmistonW.A. SminkR.D.Jr SawinH.S.Jr CamposC.T. HansenB.J. TunaN. KarnegisJ.N. SanmarcoM.E. AmplatzK. Castaneda-ZunigaW.R. HunterD.W. BissettJ.K. WeberF.J. StevensonJ.W. LeonA.S. ChalmersT.C. Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia. Report of the Program on the Surgical Control of the Hyperlipidemias (POSCH).N. Engl. J. Med.19903231494695510.1056/NEJM1990100432314042205799
     [Google Scholar]
  48. SpivakH. SakranN. DickerD. RubinM. RazI. ShohatT. BlumenfeldO. Different effects of bariatric surgical procedures on dyslipidemia: A registry-based analysis.Surg. Obes. Relat. Dis.20171371189119410.1016/j.soard.2017.03.01328456511
     [Google Scholar]
  49. SalminenP. GrönroosS. HelmiöM. HurmeS. JuutiA. JuuselaR. Peromaa-HaavistoP. LeivonenM. NuutilaP. OvaskaJ. Effect of laparoscopic sleeve gastrectomy vs roux-en-Y gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity.JAMA Surg.2022157865666610.1001/jamasurg.2022.222935731535
     [Google Scholar]
  50. DingL. FanY. LiH. ZhangY. QiD. TangS. CuiJ. HeQ. ZhuoC. LiuM. Comparative effectiveness of bariatric surgeries in patients with obesity and type 2 diabetes mellitus: A network meta‐analysis of randomized controlled trials.Obes. Rev.2020218e1303010.1111/obr.1303032286011
     [Google Scholar]
  51. SchauerP.R. BhattD.L. KirwanJ.P. WolskiK. AminianA. BrethauerS.A. Bariatric surgery versus intensive medical therapy for diabetes - 5-year outcomes.N Engl J Med.2017376764165110.1056/NEJMoa1600869
     [Google Scholar]
  52. FadhilI. BelailaB. RazzakH.A. National accountability and response for noncommunicable diseases in the United Arab Emirates.Int. J. Noncommun. Dis.201941410.4103/jncd.jncd_55_18
     [Google Scholar]
  53. AbifadelM. RabèsJ.P. JambartS. HalabyG. Gannagé-YaredM.H. SarkisA. BeainoG. VarretM. SalemN. CorbaniS. AydénianH. JunienC. MunnichA. BoileauC. The molecular basis of familial hypercholesterolemia in Lebanon: Spectrum of LDLR mutations and role of PCSK9 as a modifier gene.Hum. Mutat.2009307E682E69110.1002/humu.2100219319977
     [Google Scholar]
  54. RobinsonJ.G. Management of familial hypercholesterolemia: A Review of the recommendations from the national lipid association expert panel on familial hypercholesterolemia.J. Manag. Care Pharm.201319213914910.18553/jmcp.2013.19.2.13923461430
     [Google Scholar]
  55. ArafahM. Al-HinaiA.T. MahmeedW.A. Al-RasadiK. TamimiO.A. HerzS.A. AnaziF.A. NemerK.A. MetwallyO. AlkhadraA. FakhryM. ElghetanyH. MedaniA.R. YusufaliA.H. JassimO.A. HallaqO.A. BaslaibF.O.A.S. AlawadhiM. AminH. Al-HashmiK. ShehabA. Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia: Results from the CEPHEUS study in Arabian Gulf countries.Angiology2014651091992610.1177/000331971351241424301426
     [Google Scholar]
  56. Al SifriS.N. AlmahmeedW. AzarS. OkkehO. BramlageP. JüngerC. HalawaI. AmbegaonkarB. WajihS. BrudiP. Results of the dyslipidemia international study (DYSIS)-Middle East: Clinical perspective on the prevalence and characteristics of lipid abnormalities in the setting of chronic statin treatment.PLoS One201491e8435010.1371/journal.pone.008435024400085
     [Google Scholar]
  57. Al-RasadiK. Al-ZakwaniI. Al MahmeedW. ArafahM. Al-HinaiA.T. ShehabA. Al TamimiO. AlawadhiM. Therapeutic lipid target achievements among high and highest risk patients: Results from the CEPHEUS study in the Arabian Gulf.Curr. Med. Res. Opin.201430122429243510.1185/03007995.2014.96577425222765
     [Google Scholar]
  58. AlefishatE. JarabA.S. Al-QeremW. Abu-ZaytounL. Factors associated with medication non-adherence in patients with dyslipidemia.Healthcare20219781310.3390/healthcare907081334203226
     [Google Scholar]
/content/journals/nemj/10.2174/0102506882268432231023083154
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  • Article Type:     Review Article
Keyword(s): Dyslipidemia; Patient profile; Standard of Care; Statins-ezetimibe combination; United Arab Emirates; Unmet needs

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