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Medicinal Chemistry

ISSN: 1573-4064

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• • Synthesis and Antibacterial Evaluation of Novel Small-Molecule Antibacterials of a Reduced Acridine Structure in S. aureus Strains Including MRSA

    Authors: Peter Werner, David Kreutzer, Nikoletta Szemeredi, Gabriella Spengler and Andreas Hilgeroth

• • Synthesis, Molecular Docking Studies and Biological Evaluation of Thiazolyl Hydrazone Derivatives of Chromone-3-carbaldehyde as Potent Anti-Oxidant and Anti-Inflammatory Agents

    Authors: Rakhi Gawali, Raghunath Bhosale, Rohit Bavi, Shravan Jadhav and Nargisbano Peerzade

• • Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential

    Authors: Poonam Kumari, Neetu Agrawal and Somdutt Mujwar

• • PPARs (Peroxisome Proliferator-activated Receptors) and Their Agonists in Alzheimer's Disease

    Authors: Mohit Kumar, Anita A. Sharma, Ashok Kumar Datusalia and Gopal L. Khatik

• • Synthetic Protocols, Structural Activity Relationship, and Biological Activity of Piperazine and its Derivatives

    Authors: Md Faizan, Rajnish Kumar, Avijit Mazumder, Salahuddin, Neelima Kukreti, Arvind Kumar and M.V.N.L. Chaitanya

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• • Emerging Roles of Purinergic Signaling in Diabetes

    Authors: Carmen Fotino, Diego Dal Ben and Elena Adinolfi

• • Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

    Authors: Tugba Gungor, Gulden Yetis, Ferah C. Onder, Esra Tokay, Tugba T. Tok, Ayhan Celik, Mehmet Ay and Feray Kockar

• • Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones

    Authors: Humaira Zafar, Sarosh Iqbal, Sumaira Javaid, M. Khalid M. Khan and I. Muhammad I. Choudhary

• • Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes

    Authors: Humera Jahan, Muhammad I. Choudhary, Amber Atta, Khalid M. Khan and Atta-ur-Rahman

• • Towards the In-silico Design of New HSP90 Inhibitors: Molecular Docking and 3D-QSAR CoMFA Studies of Tetrahydropyrido [4, 3-d] Pyrimidine Derivatives as HSP90 Inhibitors

    Authors: Bakhtyar Sepehri and Raouf Ghavami

• • Synthesis, Molecular Docking and ADME Prediction of 1H-indole/5- substituted Indole Derivatives as Potential Antioxidant and Anti- Inflammatory Agents

    Authors: Archana Kumari and Rajesh K. Singh

• • Synthesis and Structure-Activity Relationship; Exploration of some Potent Anti-Cancer Phenyl Amidrazone Derivatives

    Authors: Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K. Bardaweel and Mutasem O. Taha

• • Activity of Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside, its Hydrochloride, and N,N-dialkyl Derivatives Against Non-albicans Candida Isolates

    Authors: Malgorzata A. Dawgul, Daria Grzywacz, Beata Liberek, Wojciech Kamysz and Henryk Myszka

• • Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring

    Authors: Yue Zhong, Yu-Ting Lu, Ying Sun, Nian-Guang Li, Ting Gu, Wen-Yu Wu, Shao-Peng Yu and Zhi-Hao Shi

• • Facile Synthesis, Crystal Structure, DFT Calculation and Biological Activities of 4-(2-fluorophenyl)-3-(3-methoxybenzyl)-1H-1,2,4-triazol-5 (4H)-one (5)

    Authors: Muhammad Saleem, Muhammad Rafiq, Yeon K. Jeong, Dae Won Cho, Chong-Hyeak Kim, Sung-Yum Seo, Chang-Shik Choi, Seong-Karp Hong and Ki Hwan Lee
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