Letters in Organic Chemistry - Volume 21, Issue 7, 2024

Biodiesel and oleo-chemical industries have been producing huge quantities of glycerol as a by-product. Value-added products can be synthesized from glycerol through different chemical and enzymatic reactions, such as oxidation, carbonylation, reforming, acetalyzation, etherification, dehydration, hydrogenolysis, hydrolysis, esterification, and transesterification. Glycerol is a low-cost polyol that can be converted into gly Read More

In the carbamate Schiff base compound, the molecule is stabilized by intramolecular hydrogen bonding interactions along with π···π stacking and C–H···π contacts that lead to the molecule generating diverse supramolecular architecture. The fingerprint plots associated with Hirshfeld surface analysis indicate that the most important contributions for the crystal packing are from HH/HH (81.8%), HO/OH (7.5%), and HN/NH (1.9% Read More

Our primary research objective is to create and formulate small ring heterocycles with enhanced biological efficacy. Amide functionalized trifluoromethyl thieno[2,3-b]pyridine derivatives as a series were prepared starting from reaction between 1,3 di-ketone and thiocyanoacetamide and obtained pyridine 3. Compound 3 reacts with bromoethyl acetate and obtained compound 4, further compound 4 on reaction with d Read More

>Lipid esters are prepared from mixed fatty anhydrides by esterification. These esters are high-value-added intermediates used in industrial applications. We describe the synthesis and characterization of esters using salicylic acid and mixed anhydrides with zinc oxide as catalysts. To achieve maximum reaction efficiency, we varied the mixed anhydride and studied some parameters in the reaction, such as the molar r Read More

A variety of dihydropyrimidone compounds were synthesised using an effective one-pot, multicomponent, environmentally friendly reaction of aromatic aldehydes, urea/thiourea, ethyl acetoacetate, and glycerol/ethyl lactate. To the best of our knowledge, this is the first catalyst-free strategy for the synthesis of this key scaffold with medicinal chemistry applications. Other significant aspects of the current approach co Read More

In this study, high yields of various cyclic carbonates are obtained by employing the drug celecoxib to promote the coupling reaction of CO2 and epoxide using tetrabutylammonium bromide. This strategy enables the synthesis of benzoic acid, phenylpropiolic acid, and 2, 4- quinazolinedione. In addition, the model reaction mechanism is proposed.

A protocol for the Chemoselective N-Boc protection of various types of amines has been developed. This includes heteroaryl, aliphatic, and alicyclic amines. The process makes use of malic acid as a catalyst and operates efficiently at ambient temperature without the need for solvents. This technique has been proven to effectively protect a wide range of functionalized amines containing both electron-donating and electron- Read More

In the current work, the Electro-Fenton (EF) based Reactive Orange 16 (RO16) dye treatment was studied and compared with central composite (CC) and Taguchi design (TD) statistical optimization tools. Color removal (RC) and COD decay (RCOD) were chosen responses for the effect of pH (A), electrolysis time (B), initial dye concentration (C), and current density (D). The facecentred CC design and L16 orthogonal array wer Read More

Similar affiliation error appeared in the author's affiliation in the article entitled “Review on Pyrazole Hybrids as Anti-microbial Agents”, published in Letters in Organic Chemistry, 2024, 21(4), 320-332 [1]. Details of the error and a correction are provided here. Original: Author Affiliation: 1Department of Pharmaceutical Chemistry, Bharati Vidyapeeth (Deemed to be) University, Poona College of Pharmacy, Pune, India; 2De Read More