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- Volume 31, Issue 3, 2025
Current Pharmaceutical Design - Volume 31, Issue 3, 2025
Volume 31, Issue 3, 2025
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Bioelectronic Medicines-A Novel Approach of Therapeutics in Current Epoch
Authors: Ajay Kumar, Mahendra Singh Ashawat, Vinay Pandit and Pravin KumarBackgroundBioelectronic medicines aim to diagnose and treat a wide range of illnesses and ailments, including cancer, rheumatoid arthritis, inflammatory bowel disease, obesity, diabetes, asthma, paralysis, blindness, bleeding, ischemia, organ transplantation, cardiovascular disease, and neurodegenerative diseases. The focus of bioelectronic medicine is on electrical signaling of the nervous system. Understanding the ner Read More
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- Medicine, Immunology, Inflammation & Allergy, Pharmacology
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Insight into Protein Engineering: From In silico Modelling to In vitro Synthesis
Authors: Anagha Balakrishnan, Saurav K. Mishra and John J. GeorrgeProtein engineering alters the polypeptide chain to obtain a novel protein with improved functional properties. This field constantly evolves with advanced in silico tools and techniques to design novel proteins and peptides. Rational incorporating mutations, unnatural amino acids, and post-translational modifications increases the applications of engineered proteins and peptides. It aids in developing drugs with Read More
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Recent Advancement in Drug Development for Treating Malaria using Herbal Medicine and Nanotechnological Approach
Authors: Sarvesh Bhargava, Rohitas Deshmukh and Hitesh Kumar DewanganMore than two hundred million people around the world are infected with malaria, a blood-borne disease that poses a significant risk to human life. Single medications, such as lumefantrine, primaquine, and chloroquine, as well as combinations of these medications with artemisinin or its derivatives, are currently being used as therapies. In addition, due to rising antimalarial drug resistance, other therapeutic options are n Read More
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- Medicine, Immunology, Inflammation & Allergy, Pharmacology
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Inhibition of Colorectal Cancer Metastasis by Total Flavones of Abelmoschus manihot via LncRNA AL137782-mediated STAT3/EMT Pathway Regulation
Authors: Qian Li, Hui Zhang, Yongshan He, Hao Zhang and Conghui HanBackgroundColorectal cancer (CRC) ranks among the most lethal malignancies globally, particularly following metastasis which results in poor prognosis. In recent years, CRC incidence in China has persistently increased. Total flavonoids (TFA) from Abelmoschus manihot, a natural compound, are recognized for their anti-inflammatory, analgesic, and antioxidant properties. However, despite extensive research Read More
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Improving Vaccine Response through Probiotics and Micronutrient Supplementation: Evaluating the Role of TLR5 in Adult Female BALB/c Mice
More LessBackgroundThe role of probiotics and micronutrients in improving immune system function and response to vaccination has been proven. Hence, this study aimed to investigate the effects of probiotics enriched with micronutrients on the immunogenicity of PastoCovac® vaccine.MethodsThe probiotic supplement BioBoost® and PastoCovac® vaccine, which contain six expressed Receptor-binding Domains (RBD) and conjugate Read More
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Volumes & issues
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Volume 31 (2025)
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Volume 30 (2024)
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Volume 29 (2023)
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Volume 28 (2022)
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Volume 27 (2021)
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Volume 26 (2020)
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Volume 25 (2019)
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Volume 24 (2018)
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Volume 23 (2017)
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Volume 22 (2016)
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Volume 21 (2015)
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Volume 20 (2014)
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Volume 19 (2013)
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Volume 18 (2012)
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Volume 17 (2011)
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Volume 16 (2010)
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Volume 15 (2009)
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Volume 14 (2008)
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Volume 13 (2007)
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Volume 12 (2006)
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Volume 11 (2005)
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Volume 10 (2004)
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Volume 9 (2003)
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Volume 8 (2002)
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Volume 7 (2001)
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Volume 6 (2000)
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