Current Organic Chemistry - Volume 7, Issue 2, 2003

Syntheses and reactions of β-carbonylallylsilane, conjugated allylsilane with a carbonyl group at the β-position, or its equivalent are reviewed. The method of the preparation of this moiety can be classified into (1) the introduction of silyl group at the allylic position of α,β-unsaturated carbonyl compounds, (2) carbonylation of allylsilane at the β-position, (3) elimination from pre-constructed β- silyl carbonyl compounds, (4) The H Read More

Recently, alkylation, alkenylation, and arylation of 4-cyclopentene-1,3-diol monoacetate have been published to produce 4-substituted-2-cyclopenten-1-ols (1,4- isomers) or 2-substituted-3-cyclopenten-1-ols (1,2-isomers). The product selectivity is usually high, and hence the products will provide a new access to the cyclopentanoids. This review describes scope and limitation of these reactions, synthetic advantages, co Read More

The pyrazino[2,1-b]quinazoline-3,6-dione system is the key structural fragment of a group of alkaloids. The synthesis of derivatives of this system has been accomplished by means of three kinds of methods, starting from 4(3H)-quinazolinones, 2,5-piperazinediones or open-chain tripeptides, where anthranilic acid can be at the C-terminal, the N-terminal or the intermediate position of the tripeptide. Regarding its reactivity, m Read More

Though sulfur-containing heterocyclic compound syntheses have been extensively studied, syntheses of selenium analogues have not been appreciably investigated. Recently, however, reports of selenium-containing heterocyclic compound synthesis have gradually increased not only because of their interesting reactivities but also because of their pharmaceutical applications. For example, 1,3-selenazines showed sign Read More

Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review Read More