Current Organic Chemistry - Volume 7, Issue 14, 2003

Applications of the retro Diels-Alder reaction (cycloreversion) under mild conditions for the laboratory preparation of heteromonocycles or condensed-ring heterocycles are reviewed. A new method utilizes diendo- or diexo-3-aminonorbornene-2-carboxylic acids and their derivatives for the formation of heterocyclic ring systems which are difficult to access by other routes or which can be prepared only in complicated m Read More

In this account we will present and critically analyze the different synthetic strategies that have been reported in the literature for the synthesis of kinamycin C, one the rare naturally occurring diazo compounds, with interesting biological activities.

The Paterno-Buchi reaction on furan derivatives is reviewed. The photochemical reaction of furan derivatives in the reaction with carbonyl compounds gives the corresponding monoadduct with high regio- and stereoselectivity. When the reaction is carried out in benzene, a large amount of the diadduct can be obtained. The exo stereoselectivity at C-6 was explained assuming the presence of a secondary orbital e Read More

In recent years a number of compounds containing bis-spiroacetal systems have been isolated from nature. Predominantly of dinoflagellate origin, they have stimulated much synthetic interest due to their potent biological activity and synthetically challenging structural features. Although the chemistry of bicyclic spiroacetals is well understood, that of the tricyclic bis-spiroacetals has been less fully explored. This review describ Read More

The development of novel building blocks which are capable to self-assemble and the design of artificial receptors for a given substrate are two main goals in supramolecular chemistry. Herein, we describe the synthesis and evaluation of a de novo designed new binding motif for carboxylates in polar solution, the guanidiniocarbonyl pyrroles. The thermodynamic properties of this new receptor class were intensively studied bot Read More