Current Organic Chemistry - Volume 24, Issue 10, 2020

Pyrimidine heterocycles are proven to be biologically active heterocycles, found in many biological systems, displaying a broad spectrum of biological activities including anticancer, anxiolytic, antioxidant, antiviral, antifungal, anticonvulsant, antidepressant and antibacterial activities. Recently, various synthetic approaches, synthetic strategy, the variation of substrates and study devoted towards the evaluation of biolo Read More

Boron possesses the second greatest heating value of any element that can be adopted as an energetic material in the processing of propellants and explosives. It has become the first choice as a high energy fuel for solid fuel-rich propellants because of its advantages of high theoretical combustion heat. In the actual condition, the combustion efficiency of boron-containing fuel-rich propellants is low, and the potential en Read More

Quinazoline is an organic heterocyclic molecule in which two six-membered aromatic rings are fused. Two nitrogen atoms are present in the quinazoline molecule at 1 and 3 positions that is why it is also known as 1,3-diazanaphthalene. The presence of these two nitrogen atoms in 1,3-diazanaphthalene increases the usefulness of this molecule in the field of pharmaceutical sciences. Many reactions have been reported Read More

2-Phenylcyclododecanone and 2-cyclohexylcyclododecanone derivatives were synthesized and characterized by 1H NMR, 13C NMR, HR-ESI-MS and X-ray diffraction. Their preferred conformations were analyzed by the coupling constants in the 1H NMR spectra and X-ray diffraction, which showed the skeleton ring of these derivatives containing [3333]-2-one conformation, and the phenyl groups were located at the side-exo Read More

Carbon centered molecules have been very well recognized in the past for both academic and industrial purposes. Utilizing inert element instead of carbon atom could bring more molecular complexity as well as potential binding in medicinal chemistry. We report, herein, a number of strategies for the syntheses of Ru-centered molecules starting from commercially available [RuCl2(η6-p-cymene)] dimer substituted phenyl-hetero Read More