Skip to content
2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Background

The chest X-ray (CXR) remains a widely used examination in the evaluation of patients with fever, to diagnose or rule out pneumonia. Recently, a study by our group suggested that it has no diagnostic value in patients with fever without respiratory signs and/or symptoms.

Objective

The objective of this study is to validate the results of our previous study.

Design

A retrospective study was conducted in two hospitals in the Netherlands.

Patients

All patients that were referred to the internal medicine emergency department between May 2018 and May 2019 with a suspected infection defined as fever (temperature ≥38°C) or hypothermia (temperature <36°C) or CRP ≥100µg/mL.

Main Measures

We defined our primary outcome as the number of newly diagnosed pneumonia by CXR in cases of suspected infection with no obvious site of infection and nor localizing symptoms or signs.

Key Results

We included 1052 patients, of which 106 did not have respiratory signs or symptoms. In this group, none of the CXRs (95% CI 0-2.36%) showed an infiltrate. Combined with our previous study, 176 CXRs were performed in patients with no respiratory signs or symptoms. None (95% CI 0-1.42%) showed an infiltrate.

Conclusion

Our results confirm that a CXR has no diagnostic value in the workup of fever without localizing signs or symptoms.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/1573405619666230313101934
2024-01-01
2025-04-24
The full text of this item is not currently available.

References

  1. DeWittS. ChavezS.A. PerkinsJ. LongB. KoyfmanA. Evaluation of fever in the emergency department.Am. J. Emerg. Med.201735111755175810.1016/j.ajem.2017.08.03028822610
    [Google Scholar]
  2. Sepsis: recognition, diagnosis and early managementNICE guideline2016
    [Google Scholar]
  3. PereverzevaL De StoppelaarS De HeerK Torshphoto budge korts zonder delegic focus?Nid Tajdaschar Ganeskad2019163D3780
    [Google Scholar]
  4. de StoppelaarS.F. PereverzevaL. HafkampB. LipsN. TielbekeF. RustenburgL. Hoogerheide-WiegerinckC. de HeerK. Diagnostic value of chest x-ray in patients with suspected infection and no respiratory signs or symptoms.Open Forum Infect. Dis.202076ofaa22110.1093/ofid/ofaa22132617380
    [Google Scholar]
  5. BrownL.D. CaiT.T. DasGuptaA. Interval estimation for a binomial proportion - Comment - Rejoinder.Stat. Sci.200116210113310.1214/ss/1009213286
    [Google Scholar]
  6. HanleyJ.A. Lippman-HandA. If nothing goes wrong, is everything all right? Interpreting zero numerators.JAMA1983249131743174510.1001/jama.1983.033303700530316827763
    [Google Scholar]
  7. ZenoneT. Fever of unknown origin in rheumatic diseases.Infect. Dis. Clin. North Am.200721411151135, x-xi10.1016/j.idc.2007.08.00618061091
    [Google Scholar]
  8. Yolin-RaleyD S Dagogo-JackI NiellH B The utility of routine chest radiography in the initial evaluation of adult patients with febrile neutropenia patients undergoing HSCT.J Natl Compr Canc Netw201513218418910.6004/jnccn.2015.0027
    [Google Scholar]
  9. Oude NijhuisC.S.M. GietemaJ.A. VellengaE. DaenenS.M.G.J. De BontE.S.J.M. KampsW.A. GroenH.J.M. van der JagtE.J. van der GraafW.T.A. Routine radiography does not have a role in the diagnostic evaluation of ambulatory adult febrile neutropenic cancer patients.Eur. J. Cancer200339172495249810.1016/j.ejca.2003.06.00214602135
    [Google Scholar]
  10. NaviganteA H CerchiettiL C CostantiniP Conventional chest radiography in the initial assessment of adult cancer patients with fever and neutropenia.Cancer Control.2002934635110.1177/107327480200900411
    [Google Scholar]
  11. RenoultE. ButeauC. TurgeonN. MoghrabiA. DuvalM. TapieroB. Is routine chest radiography necessary for the initial evaluation of fever in neutropenic children with cancer?Pediatr. Blood Cancer200443322422810.1002/pbc.2012715266405
    [Google Scholar]
  12. RobertsS.D. WellsG.M. GandhiN.M. YorkN.R. MaronG. RazzoukB. HaydenR.T. KasteS.C. ShenepJ.L. Diagnostic value of routine chest radiography in febrile, neutropenic children for early detection of pneumonia and mould infections.Support. Care Cancer201220102589259410.1007/s00520‑011‑1366‑722278307
    [Google Scholar]
  13. FeusnerJ. CohenR. O’LearyM. BeachB. Use of routine chest radiography in the evaluation of fever in neutropenic pediatric oncology patients.J. Clin. Oncol.19886111699170210.1200/JCO.1988.6.11.16993183701
    [Google Scholar]
  14. ClaessensY.E. DebrayM.P. TubachF. BrunA.L. RammaertB. HausfaterP. NaccacheJ.M. RayP. ChoquetC. CaretteM.F. MayaudC. LeportC. DuvalX. Early chest computed tomography scan to assist diagnosis and guide treatment decision for suspected community-acquired pneumonia.Am. J. Respir. Crit. Care Med.2015192897498210.1164/rccm.201501‑0017OC26168322
    [Google Scholar]
  15. FangY. ZhangH. XieJ. LinM. YingL. PangP. JiW. Sensitivity of chest CT for COVID-19: Comparison to RT-PCR.Radiology20202962E115E11710.1148/radiol.202020043232073353
    [Google Scholar]
  16. WongH.Y.F. LamH.Y.S. FongA.H.T. Frequency and distribution of chest radiographic findings in COVID-19 positive patients.Radiology20202962E72E7810.1148/radiol.202020116032216717
    [Google Scholar]
  17. van den BerkI.A.H. KanglieM.M.N.P. van EngelenT.S.R. BipatS. DijkgraafM.G.W. BossuytP.M.M. de MonyéW. PrinsJ.M. StokerJ. OPTimal IMAging strategy in patients suspected of non-traumatic pulmonary disease at the emergency department: Chest X-ray or ultra-low-dose CT (OPTIMACT)—a randomised controlled trial chest X-ray or ultra-low-dose CT at the ED: Design and rationale.Diagn. Progn. Res.2018212010.1186/s41512‑018‑0038‑131093568
    [Google Scholar]
  18. TofighiS. NajafiS. JohnstonS.K. GholamrezanezhadA. Low-dose CT in COVID-19 outbreak: Radiation safety, image wisely, and image gently pledge.Emerg. Radiol.202027660160510.1007/s10140‑020‑01784‑332390122
    [Google Scholar]
  19. AllinoviM. PariseA. GiacaloneM. AmerioA. DelsanteM. OdoneA. FranciA. GigliottiF. AmadasiS. DelmonteD. ParriN. MangiaA. Lung ultrasound may support diagnosis and monitoring of COVID-19 pneumonia.Ultrasound Med. Biol.202046112908291710.1016/j.ultrasmedbio.2020.07.01832807570
    [Google Scholar]
/content/journals/cmir/10.2174/1573405619666230313101934
Loading
/content/journals/cmir/10.2174/1573405619666230313101934
Loading

Data & Media loading...


  • Article Type:
    Research Article
Keyword(s): Chest X-ray; Diagnostic value; Emergency department; Fever; Pneumonia; Sepsis
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test