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2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Severe pneumonia (SP) is a common cause of septic shock and Acute Respiratory Distress Syndrome (ARDS), leading to multiorgan dysfunction syndrome. Patients with SP often require respiratory support, and SP is associated with high mortality and is a significant economic burden for hospitalized patients. Therefore, early identification and real-time monitoring of the severity of SP are crucial for improving outcomes. Previous research has reported that the lung ultrasound score (LUSS) can be used to diagnose and assess the severity of SP, guide treatment, and improve prognosis. Due to the global COVID-19 pandemic, various LUSS systems have been developed to help identify the unique characteristics of SP and reduce the risk of death. However, there is currently a lack of standardization in the use of these systems. This article provides key information about lung ultrasound (LUS) and different versions of the LUSS, aiming to standardize and simplify the clinical application of LUS and the LUSS for SP patients.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-04-24
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References

  1. ZhaoJ. HeX. MinJ. YaoR.S.Y. ChenY. ChenZ. HuangY. ZhuZ. GongY. XieY. LiY. LuoW. ShiD. XuJ. ShenA. WangQ. SunR. HeB. LinY. ShenN. CaoB. YangL. SheD. ShiY. ZhouJ. SuX. ZhouH. MaZ. FanH. LinY. YeF. NieX. ZhangQ. TianX. LaiG. ZhouM. MaJ. ZhangJ. QuJ. A multicenter prospective study of comprehensive metagenomic and transcriptomic signatures for predicting outcomes of patients with severe community-acquired pneumonia.EBioMedicine20239610479010.1016/j.ebiom.2023.10479037708700
    [Google Scholar]
  2. SoinA.S. KumarK. ChoudharyN.S. SharmaP. MehtaY. KatariaS. GovilD. DeswalV. ChaudhryD. SinghP.K. GuptaA. AgarwalV. KumarS. SangleS.A. ChawlaR. NarreddyS. PanditR. MishraV. GoelM. RamananA.V. Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): An open-label, multicentre, randomised, controlled, phase 3 trial.Lancet Respir. Med.20219551152110.1016/S2213‑2600(21)00081‑333676589
    [Google Scholar]
  3. LiuH. LiuF. LiJ. ZhangT. WangD. LanW. Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children.J. Infect.2020805e7e1310.1016/j.jinf.2020.03.00732171865
    [Google Scholar]
  4. FerreyroB.L. AngrimanF. MunshiL. Del SorboL. FergusonN.D. RochwergB. RyuM.J. SaskinR. WunschH. da CostaB.R. ScalesD.C. Association of noninvasive oxygenation strategies with all-cause mortality in adults with acute hypoxemic respiratory failure.JAMA20203241576710.1001/jama.2020.952432496521
    [Google Scholar]
  5. SearsC.R. PeikertT. PossickJ.D. NaidooJ. NishinoM. PatelS.P. CamusP. GagaM. GaronE.B. GouldM.K. LimperA.H. MontgrainP.R. TravisW.D. RiveraM.P. knowledge gaps and research priorities in immune checkpoint inhibitor-related pneumonitis. An official American Thoracic Society research statement.Am. J. Respir. Crit. Care Med.20192006e31e4310.1164/rccm.201906‑1202ST31518182
    [Google Scholar]
  6. PanF. YeT. SunP. GuiS. LiangB. LiL. ZhengD. WangJ. HeskethR.L. YangL. ZhengC. Time course of lung changes at chest CT during recovery from coronavirus disease 2019 (COVID-19).Radiology2020295371572110.1148/radiol.202020037032053470
    [Google Scholar]
  7. Rubio-GraciaJ. Giménez-LópezI. Garcés-HornaV. López-DelgadoD. Sierra-MonzónJ.L. Martínez-LostaoL. Josa-LaordenC. Ruiz-LaiglesiaF. Pérez-CalvoJ.I. Crespo-AznarezS. García-LafuenteJ. Peña FresnedaN. Amores ArriagaB. Gracia-TelloB. Sánchez-MartelesM. Point-of-care lung ultrasound assessment for risk stratification and therapy guiding in COVID-19 patients: A prospective noninterventional study.Eur. Respir. J.2021583200428310.1183/13993003.04283‑202033574074
    [Google Scholar]
  8. de Almeida MonteiroR.A. Duarte-NetoA.N. Ferraz da SilvaL.F. de OliveiraE.P. do NascimentoE.C.T. MauadT. SaldivaP.H.N. DolhnikoffM. Ultrasound assessment of pulmonary fibroproliferative changes in severe COVID-19: A quantitative correlation study with histopathological findings.Intensive Care Med.202147219920710.1007/s00134‑020‑06328‑433392642
    [Google Scholar]
  9. EltahlawiM. RoshdyH. WalaaM. ManthouP. GaraygordobilD.A. ElshabrawyM. ElkholyM. BashaM.A. TharwatM. MansourW. A new scoring model to diagnose COVID-19 using lung ultrasound in the emergency department.Egypt. J. Bronchol.2022161910.1186/s43168‑021‑00102‑w
    [Google Scholar]
  10. PengQ.Y. WangX.T. ZhangL.N. Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic.Intensive Care Med.202046584985010.1007/s00134‑020‑05996‑632166346
    [Google Scholar]
  11. LazzeriC. BonizzoliM. BatacchiS. SocciF. Matucci-CerinicM. PerisA. Combined lung and cardiac ultrasound in COVID-related acute respiratory distress syndrome.Intern. Emerg. Med.20211671779178510.1007/s11739‑021‑02646‑733704675
    [Google Scholar]
  12. ZieleskiewiczL. MarkarianT. LopezA. TaguetC. MohammediN. BoucekineM. BaumstarckK. BeschG. MathonG. DuclosG. BouvetL. MicheletP. AllaouchicheB. ChaumoîtreK. Di BisceglieM. LeoneM. Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia.Intensive Care Med.20204691707171310.1007/s00134‑020‑06186‑032728966
    [Google Scholar]
  13. SezginC. GunalpM. GencS. AcarN. UstunerE. OguzA.B. TanriverdiA.K. DemirkanA. PolatO. Diagnostic value of bedside lung ultrasonography in pneumonia.Ultrasound Med. Biol.20204651189119610.1016/j.ultrasmedbio.2020.01.01432063393
    [Google Scholar]
  14. MaggiL. De FazioG. GuglielmiR. COVID-19 lung ultrasound scores and lessons from the pandemic: A narrative review.Diagnostics20131311197210.1016/j.ultrasmedbio.2012.03.00122579543
    [Google Scholar]
  15. SoldatiG. InchingoloR. SmargiassiA. SherS. NennaR. InchingoloC.D. ValenteS. Ex vivo lung sonography: Morphologic-ultrasound relationship.Ultrasound Med. Biol.20123871169117910.1016/j.ultrasmedbio.2012.03.00122579543
    [Google Scholar]
  16. Alonso-OjembarrenaA. Lechuga-SanchoA.M. Ruiz-GonzálezE. González-Haba-MartínezB. Lubián-LópezS.P. Pleural line thickness reference values for preterm and term newborns.Pediatr. Pulmonol.20205592296230110.1002/ppul.2492032573932
    [Google Scholar]
  17. StassenJ. BaxJ.J. How to do lung ultrasound.Eur. Heart J. Cardiovasc. Imaging202223444744910.1093/ehjci/jeab24134791145
    [Google Scholar]
  18. DemiL. van HoeveW. van SlounR.J.G. SoldatiG. DemiM. Determination of a potential quantitative measure of the state of the lung using lung ultrasound spectroscopy.Sci. Rep.2017711274610.1038/s41598‑017‑13078‑928986558
    [Google Scholar]
  19. SoldatiG. SmargiassiA. DemiL. InchingoloR. Artifactual lung ultrasonography: It is a matter of traps, order, and disorder.Appl. Sci. (Basel)2020105157010.3390/app10051570
    [Google Scholar]
  20. SoldatiG. DemiM. SmargiassiA. InchingoloR. DemiL. The role of ultrasound lung artifacts in the diagnosis of respiratory diseases.Expert Rev. Respir. Med.201913216317210.1080/17476348.2019.156599730616416
    [Google Scholar]
  21. Morvai-IllésB. Polestyuk-NémethN. SzabóI.A. MonokiM. GarganiL. PicanoE. VargaA. ÁgostonG. The prognostic value of lung ultrasound in patients with newly diagnosed heart failure with preserved ejection fraction in the ambulatory setting.Front. Cardiovasc. Med.2021875814710.3389/fcvm.2021.75814734926610
    [Google Scholar]
  22. LuW. ZhangS. ChenB. ChenJ. XianJ. LinY. ShanH. SuZ.Z. A clinical study of noninvasive assessment of lung lesions in patients with coronavirus disease-19 (COVID-19) by bedside ultrasound.Ultraschall Med.202041330030710.1055/a‑1154‑879532294796
    [Google Scholar]
  23. VolpicelliG. GarganiL. PerliniS. SpinelliS. BarbieriG. LanotteA. CasasolaG.G. Nogué-BouR. LamorteA. AgricolaE. VillénT. DeolP.S. NazerianP. CorradiF. StefanoneV. FragaD.N. NavalesiP. FerreR. BoeroE. MartinelliG. CristoniL. PeraniC. VetrugnoL. McDermottC. Miralles-AguiarF. SeccoG. ZatteraC. SalinaroF. GrignaschiA. BoccatondaA. GiostraF. InfanteM.N. CovellaM. IngallinaG. BurkertJ. FrumentoP. ForforiF. GhiadoniL. FraccaliniT. VendrameA. BasileV. CiprianoA. FrassiF. SantiniM. FalconeM. MenichettiF. BarcellaB. DelorenzoM. RestaF. VezzoniG. BonzanoM. BrigantiD.F. CappaG. ZuninoI. DemitryL. VignaroliD. ScattagliaL. Di PietroS. BazziniM. CapozzaV. GonzálezM.M. GibalR.V. IbarzR.P. AlfaroL.M. AlfaroC.M. AlinsM.G. BrownA. DunlopH. RalliM.L. PersonaP. RusselF.M. PangP.S. RovidaS. DeanaC. FranchiniD. Lung ultrasound for the early diagnosis of COVID-19 pneumonia: An international multicenter study.Intensive Care Med.202147444445410.1007/s00134‑021‑06373‑733743018
    [Google Scholar]
  24. MillingtonS.J. KoenigS. MayoP. VolpicelliG. Lung ultrasound for patients with coronavirus disease 2019 pulmonary disease.Chest2021159120521110.1016/j.chest.2020.08.205432835709
    [Google Scholar]
  25. VolpicelliG. LamorteA. VillénT. What’s new in lung ultrasound during the COVID-19 pandemic.Intensive Care Med.20204671445144810.1007/s00134‑020‑06048‑932367169
    [Google Scholar]
  26. GarganiL. Soliman-AboumarieH. VolpicelliG. CorradiF. PastoreM.C. CameliM. Why, when, and how to use lung ultrasound during the COVID-19 pandemic: Enthusiasm and caution.Eur. Heart J. Cardiovasc. Imaging202021994194810.1093/ehjci/jeaa16332515793
    [Google Scholar]
  27. LichtensteinD.A. BLUE-protocol and FALLS-protocol: Two applications of lung ultrasound in the critically ill.Chest201514761659167010.1378/chest.14‑131326033127
    [Google Scholar]
  28. AllinoviM. PariseA. GiacaloneM. AmerioA. DelsanteM. OdoneA. FranciA. GigliottiF. AmadasiS. DelmonteD. ParriN. MangiaA. Lung ultrasound may support diagnosis and monitoring of COVID-19 pneumonia.Ultrasound Med. Biol.202046112908291710.1016/j.ultrasmedbio.2020.07.01832807570
    [Google Scholar]
  29. JiL. CaoC. GaoY. ZhangW. XieY. DuanY. KongS. YouM. MaR. JiangL. LiuJ. SunZ. ZhangZ. WangJ. YangY. LvQ. ZhangL. LiY. ZhangJ. XieM. Prognostic value of bedside lung ultrasound score in patients with COVID-19.Crit. Care202024170010.1186/s13054‑020‑03416‑133353548
    [Google Scholar]
  30. MentoF. KhanU. FaitaF. SmargiassiA. InchingoloR. PerroneT. DemiL. State of the Art in Lung Ultrasound, Shifting from Qualitative to Quantitative Analyses.Ultrasound Med. Biol.202248122398241610.1016/j.ultrasmedbio.2022.07.00736155147
    [Google Scholar]
  31. SoummerA. PerbetS. BrissonH. ArbelotC. ConstantinJ.M. LuQ. RoubyJ.J. Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress.Crit. Care Med.20124072064207210.1097/CCM.0b013e31824e68ae22584759
    [Google Scholar]
  32. VolpicelliG. ElbarbaryM. BlaivasM. LichtensteinD.A. MathisG. KirkpatrickA.W. MelnikerL. GarganiL. NobleV.E. ViaG. DeanA. TsungJ.W. SoldatiG. CopettiR. BouhemadB. ReissigA. AgricolaE. RoubyJ.J. ArbelotC. LiteploA. SargsyanA. SilvaF. HoppmannR. BreitkreutzR. SeibelA. NeriL. StortiE. PetrovicT. International evidence-based recommendations for point-of-care lung ultrasound.Intensive Care Med.201238457759110.1007/s00134‑012‑2513‑422392031
    [Google Scholar]
  33. KalkanisA. SchepersC. LouvarisZ. GodinasL. WautersE. TestelmansD. LorentN. Van MolP. WautersJ. De WeverW. DoomsC. Lung aeration in COVID-19 pneumonia by ultrasonography and computed tomography.J. Clin. Med.20221110271810.3390/jcm1110271835628846
    [Google Scholar]
  34. ChiumelloD. Bedside ultrasound assessment of positive end expiratory pressure-induced lung recruitment.Am. J. Respir. Crit. Care Med.2012185445745810.1164/ajrccm.185.4.45722336681
    [Google Scholar]
  35. BaldiG. GarganiL. AbramoA. D’ErricoL. CaramellaD. PicanoE. GiuntaF. ForforiF. Lung water assessment by lung ultrasonography in intensive care: a pilot study.Intensive Care Med.2013391748410.1007/s00134‑012‑2694‑x23052950
    [Google Scholar]
  36. MongodiS. BouhemadB. OrlandoA. StellaA. TavazziG. ViaG. IottiG. BraschiA. MojoliF. Modified lung ultrasound score for assessing and monitoring pulmonary aeration.Ultraschall Med.201738553053710.1055/s‑0042‑12026028291991
    [Google Scholar]
  37. MongodiS. ViaG. GirardM. RouquetteI. MissetB. BraschiA. MojoliF. BouhemadB. Lung ultrasound for early diagnosis of ventilator-associated pneumonia.Chest2016149496998010.1016/j.chest.2015.12.01226836896
    [Google Scholar]
  38. SoldatiG. SmargiassiA. InchingoloR. Proposal for international standardization of the use of lung ultrasound for patients with COVID‐19: A simple, quantitative, reproducible method.J. Ultrasound Med.20203971413141910.1002/jum.1528532227492
    [Google Scholar]
  39. ChenJ. QiT. LiuL. LingY. QianZ. LiT. LiF. XuQ. ZhangY. XuS. SongZ. ZengY. ShenY. ShiY. ZhuT. LuH. Clinical progression of patients with COVID-19 in Shanghai, China.J. Infect.2020805e1e610.1016/j.jinf.2020.03.00432171869
    [Google Scholar]
  40. GutscheH. LesserT.G. WolframF. DoenstT. Significance of lung ultrasound in patients with suspected COVID-19 infection at hospital admission.Diagnostics (Basel)202111692110.3390/diagnostics1106092134063861
    [Google Scholar]
  41. SkopljanacI. IveljaM.P. BarcotO. BrdarI. DolicK. PolasekO. RadicM. Role of lung ultrasound in predicting clinical severity and fatality in COVID-19 pneumonia.J. Pers. Med.202111875710.3390/jpm1108075734442401
    [Google Scholar]
  42. GualtierottiR. TafuriF. RossioR. RotaM. BucciarelliP. FerrariB. GiachiA. SuffrittiC. CugnoM. PeyvandiF. Lung ultrasound findings and endothelial perturbation in a COVID-19 low-intensity care unit.J. Clin. Med.20221118542510.3390/jcm1118542536143072
    [Google Scholar]
  43. PerroneT. SoldatiG. PadoviniL. FiengoA. LettieriG. SabatiniU. GoriG. LeporeF. GarolfiM. PalumboI. InchingoloR. SmargiassiA. DemiL. MossolaniE.E. TursiF. KlersyC. Di SabatinoA. A new lung ultrasound protocol able to predict worsening in patients affected by severe acute respiratory syndrome coronavirus 2 pneumonia.J. Ultrasound Med.20214081627163510.1002/jum.1554833155689
    [Google Scholar]
  44. FalgaroneG. PamoukdjianF. CailholJ. Giocanti-AureganA. GuisS. BousquetG. BouchaudO. SerorO. Lung ultrasound is a reliable diagnostic technique to predict abnormal CT chest scan and to detect oxygen requirements in COVID-19 pneumonia.Aging (Albany NY)20201220199451995310.18632/aging.10415033136555
    [Google Scholar]
  45. BiasucciD.G. BuonsensoD. PianoA. BonadiaN. VargasJ. SettanniD. BocciM.G. GriecoD.L. CarnicelliA. ScoppettuoloG. EleuteriD. De PascaleG. PennisiM.A. FranceschiF. AntonelliM. Lung ultrasound predicts non-invasive ventilation outcome in COVID-19 acute respiratory failure: A pilot study.Minerva Anestesiol.20218791006101610.23736/S0375‑9393.21.15188‑034263580
    [Google Scholar]
  46. BiasucciD.G. BocciM.G. BuonsensoD. PisapiaL. ConsalvoL.M. VargasJ. GriecoD.L. De PascaleG. AntonelliM. Thromboelastography profile is associated with lung aeration assessed by point-of-care ultrasound in COVID-19 critically ill patients: An observational retrospective study.Healthcare (Basel)2022107116810.3390/healthcare1007116835885695
    [Google Scholar]
  47. GuarracinoF. VetrugnoL. ForforiF. CorradiF. OrsoD. BertiniP. OrtaldaA. FedericiN. CopettiR. BoveT. Lung, heart, vascular, and diaphragm ultrasound examination of COVID-19 patients: A comprehensive approach.J. Cardiothorac. Vasc. Anesth.20213561866187410.1053/j.jvca.2020.06.01332624431
    [Google Scholar]
  48. GuoT. FanY. ChenM. WuX. ZhangL. HeT. WangH. WanJ. WangX. LuZ. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19).JAMA Cardiol.20205781181810.1001/jamacardio.2020.101732219356
    [Google Scholar]
  49. WangD. HuB. HuC. ZhuF. LiuX. ZhangJ. WangB. XiangH. ChengZ. XiongY. ZhaoY. LiY. WangX. PengZ. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China.JAMA2020323111061106910.1001/jama.2020.158532031570
    [Google Scholar]
  50. HuangC. WangY. LiX. RenL. ZhaoJ. HuY. ZhangL. FanG. XuJ. GuX. ChengZ. YuT. XiaJ. WeiY. WuW. XieX. YinW. LiH. LiuM. XiaoY. GaoH. GuoL. XieJ. WangG. JiangR. GaoZ. JinQ. WangJ. CaoB. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.Lancet20203951022349750610.1016/S0140‑6736(20)30183‑531986264
    [Google Scholar]
  51. PeñuelasO. KeoughE. López-RodríguezL. CarriedoD. GonçalvesG. BarreiroE. LorenteJ.Á. Ventilator-induced diaphragm dysfunction: Translational mechanisms lead to therapeutical alternatives in the critically ill.Intensive Care Med. Exp.20197Suppl 14810.1186/s40635‑019‑0259‑931346802
    [Google Scholar]
  52. KlokF.A. KruipM.J.H.A. van der MeerN.J.M. ArbousM.S. GommersD.A.M.P.J. KantK.M. KapteinF.H.J. van PaassenJ. StalsM.A.M. HuismanM.V. EndemanH. Incidence of thrombotic complications in critically ill ICU patients with COVID-19.Thromb. Res.202019114514710.1016/j.thromres.2020.04.01332291094
    [Google Scholar]
  53. Dell’AquilaP. RaimondoP. RacanelliV. De LucaP. De MatteisS. PistoneA. MelodiaR. CrudeleL. LomazzoD. SolimandoA.G. MoschettaA. VaccaA. GrassoS. ProcacciV. OrsoD. VetrugnoL. Integrated lung ultrasound score for early clinical decision-making in patients with COVID-19: Results and implications.Ultrasound J.20221412110.1186/s13089‑022‑00264‑835648278
    [Google Scholar]
  54. CasellaF. BarchiesiM. LeidiF. RussoG. CasazzaG. ValerioG. TorzilloD. CerianiE. Del MedicoM. BrambillaA.M. MazziottiM.A. CogliatiC. Lung ultrasonography: A prognostic tool in non-ICU hospitalized patients with COVID-19 pneumonia.Eur. J. Intern. Med.202185344010.1016/j.ejim.2020.12.01233663708
    [Google Scholar]
  55. DargentA. ChatelainE. KreitmannL. QuenotJ.P. CourM. ArgaudL. Lung ultrasound score to monitor COVID-19 pneumonia progression in patients with ARDS.PLoS One2020157e023631210.1371/journal.pone.023631232692769
    [Google Scholar]
  56. MojoliF. BouhemadB. MongodiS. LichtensteinD. Lung ultrasound for critically ill patients.Am. J. Respir. Crit. Care Med.2019199670171410.1164/rccm.201802‑0236CI30372119
    [Google Scholar]
  57. TaniguchiH. OhyaA. YamagataH. IwashitaM. AbeT. TakeuchiI. Prolonged mechanical ventilation in patients with severe COVID-19 is associated with serial modified-lung ultrasound scores: A single-centre cohort study.PLoS One2022177e027139110.1371/journal.pone.027139135830460
    [Google Scholar]
  58. GoligherE.C. DresM. FanE. RubenfeldG.D. ScalesD.C. HerridgeM.S. VoronaS. SklarM.C. RittayamaiN. LanysA. MurrayA. BraceD. UrreaC. ReidW.D. TomlinsonG. SlutskyA.S. KavanaghB.P. BrochardL.J. FergusonN.D. Mechanical ventilation–induced diaphragm atrophy strongly impacts clinical outcomes.Am. J. Respir. Crit. Care Med.2018197220421310.1164/rccm.201703‑0536OC28930478
    [Google Scholar]
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