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- Volume 18, Issue 4, 2023
Current Drug Therapy - Volume 18, Issue 4, 2023
Volume 18, Issue 4, 2023
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Computational Techniques for Drug Repurposing: A Paradigm Shift in Drug Discovery
Authors: Monica R. P. Rao, Isha S. Ghadge, Saurav Prasanna Kulkarni and Tanya AsthanaThe last two years from 2020 to 2022 have seen the world face an unparalleled crisis in the form of the corona virus, which has challenged mankind as never before. The struggle and race to find a cure for the disease kept medical professionals, pharmacists, and scientists on their toes. Drug discovery by de novo approach was not an option due to its obvious downside of the enormous time required for the process. Hith Read More
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Saraca asoca: From Traditional Herb to Modern Drug as a Cure for Various Diseases
Background: Saraca asoca (Ashoka, family; Caesalpiniaceae) is an indigenous sacred tree, native to India. It has been used in various traditional medicinal systems and is one such plant that is highly therapeutic but its use in disease management is underrated in today’s era and has lost its importance. Objective: This narrative review is written to provide the information on medicinal importance of S. asoca and the significan Read More
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Tea tree (Melaleuca alternifolia) Essential Oil Concentration in Microemulsion with Antibacterial and Antifungal Activity: An Overview
Authors: Prashant Upadhyay, Pooja Malik and Sukirti UpadhyayThe tea tree (Melaleuca alternifolia), a member of the Myrtaceae family, is a valuable medicinal and aromatic plant. Tea Tree essential oil (TTO) has many medical applications, including antibacterial, antifungal, antiviral, antiprotozoal, anti-inflammatory, antioxidant, and anticancer properties. Although the concentration of TTO in a microemulsion is of economic interest, very few studies on this product have been conducted. In Read More
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Picoscience: Picotechnology’s Advent in Health and Medicine
As the human race evolves, numerous diseases have dominated humans, causing scientists to encounter myriad challenges with formulations. To rectify these issues, Nanoparticle (10-9 m) formulation approach or nanotechnology has been developed. Since nanoparticles have legion benefits, encompassing better bioavailability, target-specific, confined, accurate dose delivery, and increased surface area, are pertinent for effe Read More
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Safety and Efficacy of Genistein in Sanfilippo Syndrome - A Systematic Review
Authors: Haya Majid, Md. Masoom, Mohd. A. Khan and Aakriti GargBackground: Sanfilippo syndrome, commonly known as mucopolysaccharidosis type III (MPS III), is a rare autosomal recessive lysosomal storage disease that primarily affects the brain and spinal cord. It is caused by a deficiency of enzymes involved in the catabolism of glycosaminoglycan (GAG) and heparin sulfate (HS). Although Genistein has been presented as a potential therapeutic, its safety and efficacy for the treatme Read More
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Antifungal Properties of Pinus eldarica and Pinus longifolia Fruit Extracts against Candida Species Isolated from Vulvovaginal Candidiasis Patients
Authors: Zohre Norouzi, Mahboobeh Madani, Leila Amjad and Pegah ShakibIntroduction: Candidiasis is a disease with serious problems in women. With the increasing drug resistance and risks of the drugs, we investigated the effect of different cone extracts of Pinus eldarica and Pinus longifolia against Candida species isolated from vulvovaginal candidiasis patients. Materials and Methods: Candida species isolated from 50 patients were identified by routine mycological methods, including morphology Read More
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An Approach to Treat Conundrum of Skin Cancer: Bioactive Loaded Niosomes
Authors: Shikha Srivastava and Divya SharmaBackground: Skin cancer is one of the most life-threatening and progressive diseases nowadays, majorly resulting from the cumulative effect of genetic and environmental exposure including UV rays and numerous pollutants. UV radiation stimulates the excessive generation of Reactive oxygen species (ROS) and Reactive nitrogen species (RNS), altering numerous signaling and inflammatory pathways and cumulatively ca Read More
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Evaluation of the Effectiveness of Remdesivir in the Treatment of COVID-19 Outpatients: A Retrospective Cohort Study
Background: The outbreak of acute respiratory syndrome with novel coronavirus 2019 (COVID-19) in December 2019 in Wuhan, China, caused a worldwide outbreak of the disease. To treat the disease, some drugs were identified and introduced that did not show a significant effect on the recovery of the disease. Due to the need to manage inpatient beds, this study was conducted to evaluate the effectiveness of Remdesivi Read More
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Volumes & issues
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Volume 20 (2025)
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Volume 19 (2024)
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Volume 18 (2023)
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Volume 17 (2022)
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Volume 16 (2021)
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Volume 15 (2020)
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Volume 14 (2019)
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Volume 13 (2018)
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Volume 12 (2017)
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Volume 11 (2016)
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Volume 10 (2015)
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Volume 9 (2014)
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Volume 8 (2013)
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Volume 7 (2012)
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Volume 6 (2011)
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Volume 5 (2010)
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Volume 4 (2009)
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Volume 3 (2008)
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Volume 2 (2007)
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Volume 1 (2006)
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