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Glutathione-responsive Nanoparticles for Optimized Cas9/sgRNA Gene Editing Delivery
Authors: Md Sadique Hussain, Ajay Singh Bisht, Haider Ali and Gaurav GuptaAvailable online: 11 April 2025More Less
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The Role of Glycolipids and their Toxicity in the Context of Nanomaterials and Nanoparticles: A Review of the Literature
Authors: Moyu Li, Wenjin Peng, Siwei Zhu, Xianyu Chen, Li Li, Xiaolan Li and Chengfu YuanAvailable online: 10 March 2025More LessBackground Diseases triggered by glucose and lipid metabolic disorders, such as hyperglycemia and hyperlipidemia, have become a global health threat. According to statistics, diabetic patients have exceeded 463 million worldwide, and the prevalence of hyperlipidemia is also continuously rising. These glycolipid metabolic diseases not only significantly increase the risk of complications such as cardiovascular disease, stroke Read More
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Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment
Available online: 24 February 2025More LessGlobally, high mortality is brought on by RNA viruses, which are linked to chronic human disorders. Viruses dominate the WHO's current ranking of the top 10 global health hazards, especially RNA viruses. RNA viruses, like HIV, SARS-CoV-2, and influenza, which are among the most prevalent and frequently encountered RNA viruses, use RNA as their genetic material, making them prone to quick changes. They adapt rapidly, compl Read More
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Emerging Carbon Dots Nanomaterials for Ovarian Cancer Diagnosis and Therapy
Available online: 04 February 2025More LessDelayed diagnosis and limited treatment options make ovarian cancer difficult to treat. This paper examines the growing role of Carbon Dots (CDs) in ovarian cancer diagnosis and treatment. Photoluminescence and biocompatibility make CDs ideal for biomedical use. We emphasize their ability to improve fluorescence and molecular imaging in imaging and diagnostics. We also demonstrate the efficacy of carbon dots in targeted Read More
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MT1JP: A Pivotal Tumor-Suppressing LncRNA and its Role in Cancer Progression and Therapeutic Potential
Authors: Haodong He, Jingjie Yang, Wenjin Peng, Moyu Li, Meiyan Shuai, Faming Tan, Zheng Cao and Chengfu YuanAvailable online: 22 January 2025More LessMetallothionein 1J pseudogene (MT1JP) is a long non-coding RNA (lncRNA) that functions as a tumor suppressor in various malignancies. Reduced MT1JP expression is associated with increased tumor proliferation, migration, invasion, epithelial-mesenchymal transition (EMT), and treatment resistance in nine cancers, such as gastric cancer, intrahepatic cholangiocarcinoma, hepatocellular carcinoma, and breast cancer. Mech Read More
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New Advances in Drug Research for Myopia Control in Adolescents
Authors: Yu Liu and Yalong DangAvailable online: 20 January 2025More LessBackground Myopia is one of the most common eye diseases worldwide, with an increasing incidence observed in recent years. Globally, effective treatments for myopia have been extensively explored. In recent years, research on drugs for the treatment of myopia has become a popular topic in ophthalmology, with some breakthroughs having been achieved. Compared with surgical treatment, drug treatment is easier for peo Read More
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