Current Analytical Chemistry - Volume 20, Issue 8, 2024

Aims: Applicability of QbD-assisted analytical method for simultaneous detection of tetrahydrocurcumin and folic acid in developed nanostructured lipid carriers. Background: Diabetic foot ulcer (DFU) is a multifactorial disorder that involves chronic inflammation, oxidative stress and neuropathy. Current treatment therapies involving the use of growth factors and skin substitutes being costly, are out of reach for the majority of pat Read More

Background: The zero-field splitting parameters of Mn2+gt; doped L-histidine-4- nitrophenolate 4-nitrophenol single crystals are evaluated. Methods: The superposition model and perturbation theory are used to obtain zero-field splitting parameters for Mn2+ ion-doped LHPP single crystals. The optical spectra of the system are computed using the crystal field parameters from the superposition model as input into t Read More

Background: Polystyrene nanospheres are used as a substrate for the hydrothermal coating of tungsten trioxide (WO3 ) to form a core-shell composite of PS@WO3 . The core-shell structure is used for the next sintering step. This produces porous WO3 . The focus of this study is on the role of porous WO3 in enhancing photocatalytic performance. Methods: The hydrothermal method was employed for coating, and the s Read More

gt;Introduction: In this work, a polyacrylate polymer was synthesized into a pipette tip containing cotton fibers and used to extract carvedilol from water and urine samples. Methods: A high-performance liquid chromatography-ultraviolet detection method was developed, which demonstrated the suitability of the purposed pipette tip micro-solid-phase extraction device. Factors affecting the fabrication procedure and polymer q Read More

Background: Chlorogenic acid, an ester of caffeic acid with quinic acid, also known as 5- O-caffeoylquinic acid (5-CQA), is a ubiquitous plant constituent that is an important intermediate in lignin biosynthesis. In some cases, it occurs at surprisingly high levels in the leaves and fruits of certain higher plants, such as coffee beans. Due to its catechol moiety and an extended side chain conjugation, it easily forms a resonan Read More

Background: Hydrazine may induce gene abnormalities, cancer, and severe damage to the liver, lungs, kidneys, and central nervous system. Therefore, the development of reliable analytical techniques with high selectivity and sensitivity to detect hydrazine is required for the protection of human health and safety. Objectives: Traditional methods for detecting N2H4 are frequently time-consuming, less accurate, and unsuita Read More

Introduction: Camptothecin (CPT) is pivotal in cancer treatment, derived from various CPT-producing plant species, and is a fundamental component in synthesizing valuable cancer drugs like Irinotecan and Topotecan. Sourcing from nature poses conservation issues, fostering interest in the herbaceous Ophiorrhiza plant as a more sustainable alternative. Ophiorrhiza species in Sri Lanka lack comprehensive study, warr Read More