Current Analytical Chemistry - Volume 20, Issue 1, 2024

Sarcosine is currently identified as a potential biomarker for prostate cancer. It is n-methyl derivative of glycine, which is naturally present in muscle and body tissues. Studies indicate that a delay in the treatment of prostate cancer is often due to its diagnosis not being possible at earlier stages. Also, plasma and urine samples with increased sarcosine concentration exhibit a higher probability of this cancer development, t Read More

Background: Detection and identification of a wide range of drugs, including small peptides, corticosteroids, selective androgen receptor modulators (SARMs), and quaternary ammonium drugs (QADs), are imperative across several domains, particularly in anti-doping analysis, given the potential misuse of these substances in animal sports, there is an urgent demand for an allencompassing screening method to effec Read More

Background: Selective serotonin reuptake inhibitors (SSRIs) are mostly prescribed for the treatment of depression. This study describes the microscale in-microwell formation of blue-colored N-vinylamino-naphthoquinone derivatives of SSRIs upon their reaction with 2,3-dichloro-1,4- naphthoquinone (DCNQ) and acetaldehyde. The reaction was subsequently utilized as a basis for the development of a new simple and s Read More

Background: The current study presents a method for the simultaneous quantification of atractylenolide I, II, and III, together with syringin, syringaresinol-4-O-β-D-glucoside and caffeine in Atractylode macrocephala (AM) rhizomes. Contents of the metabolites, in combination with the metabolomics approach, were used to discriminate AM rhizomes, which were processed by different methods. Methods: An HPLC Agilen Read More

Background: Brown coals are recognized as promising sources of rare earth elements (REEs). Rare earths are present in both the mineral and organic parts of brown coal. Objectives: This study was conducted to investigate the influence of preliminary mechanical activation in the process of sample preparation prior to analyzing the concentrations of rare earth elements in brown coal samples of various origins and compos Read More

Introduction: This paper first introduces the use of computer-simulated single-band synchronous fluorescence (SF) obtained from experimental excitation and emission fluorescence spectra of a pure compound in solution. The simulation produces a single narrow band with a peak wavelength that identifies the compound. Methods: The method is used to show single peak identification of benzene, chlorobenzene, b Read More