Current Analytical Chemistry - Volume 20, Issue 6, 2024

In today's era, detection of disease is utmost important for the management of disease. Early detection leads to early management of disease. Paper-based microfluidic devices are promising technologies that are cost-effective, portable and easy to use over conventional methods. In addition, paper-based microfluidics offers low reagent/sample volume, less response time and can be used in resource-limited settings. Read More

The use of organophosphate pesticides (OPPs) in agricultural practices improves crop yield and controls pests, but their indiscriminate use and persistence in the environment pose significant health risks. Therefore, it has become increasingly important to develop reliable and efficient detection methods for OPPs to ensure food safety and monitor their presence. In recent years, OPP detection methods have undergone Read More

Background: The wastewater released from various industries contains substantial amounts of organic compounds such as dyes and naphthols. However, naphthols are toxic to the environment and human health. So, it is essential to eliminate them, which will contribute to manufacturing and environmental management. Methods: In the work, an eco-friendly method is adapted to synthesize reduced graphene oxide (rGO) Read More

Background: Determination of environmental pollutants is important due to their harmful effects on the health of living organisms. However, direct measurement of many of these pollutants is not possible due to their low concentrations, which necessitates the need for sample preparation methods. One of the rapid and simple sample preparation methods is the Air-Agitated Liquid-Liquid Microextraction (AALLME) method, w Read More

Objective: This paper describes a new, digital image colourimetry-based format for the quantification of analytes in an aqueous solution. Methods: The proposed method is based on analyte pre-concentration by adsorption onto Bentone LT. Bentone LT pellet isolation comes after adsorption, followed by in-situ application of an analyteselective chromogenic reaction. The resulting pellet colouration is captured by the phone’s in Read More

Background: PYX-106 is a novel monoclonal antibody (mAb), targeting the sialic acidbinding immunoglobulin-like lectin 15 (Siglec-15) in the Tumor Microenvironment (TME). Precise measurement of PYX-106 is essential for the thorough assessment of PYX-106 pharmacokinetics in clinical investigations. Methods: A novel Electrochemiluminescence (ECL) immunoassay for the quantitation of PYX- 106 in human serum was de Read More