Current Analytical Chemistry - Volume 20, Issue 7, 2024

Biophysical techniques include various methodologies applied in studying biological systems at the molecular and cellular level for the drug discovery process. Various methods like isothermal calorimetry, electron microscopy, XRD (X-ray diffraction), electron microscopy, mass spectrometry, atomic force microscopy, differential scanning calorimetry, surface plasmon resonance, and nuclear magnetic resonance Read More

Background: Tetracycline (TC), a commonly used antibiotic, is extensively utilized in the medical sector, leading to a significant annual discharge of tetracycline effluent into the water system, which harms both human health and the environment. Objective: A novel technique was developed to address the issues of photogenerated carrier complexation and photocatalyst immobilization. Compared to traditional photocatalytic ph Read More

Introduction: A simple, precise, and sensitive UV spectrophotometric method was developed to estimate Imipramine and Ferulic acid in bulk and polymeric micelles formulation. Moreover, imipramine and ferulic acid showed maximum absorbance at 237 nm and 216 nm. Methods: The method was validated for linearity, accuracy, precision, robustness, and ruggedness. The detector response for the imipramine and feru Read More

Introduction: This study synthesizes and characterizes a novel hybrid composite, SGdpm, to capture UO22+ ions from water. The composite has successfully formed by hosting covalently diphenylmethane-1,3-dione (dpm) within an inorganic silica gel matrix, showing promising potential for environmental remediation and nuclear waste management. Methods: The preparation involved the reaction of tetraethylorthosilicate ( Read More

Introduction: Lung carcinoma presents an aggressive evolution, with its carriers having reduced survival. Late diagnosis is one of the main factors of death. In the neoplasia in question, there is an established correlation with increases in Alpha-Fetoprotein (AFP) serum concentrations. Methods: Commonly used diagnostic methods are invasive or inaccessible. Therefore, a low-cost, non-invasive method would be extremely promi Read More

Background: Thyroid hormones play an important role in cognition and brain development. The determination of the content of levothyroxine, as well as related substances and dissolution test analysis, should be carried out by methods that are selective and highly sensitive due to the low concentration used in low dose orodispersible minitablets. Objectives: This study aims to develop and validate an analytical method by H Read More