Current Analytical Chemistry - Volume 16, Issue 5, 2020

Nowadays, most advanced technologies utilize materials from finite non-renewable resources, such as fossil fuels, minerals, and metal ores. With the recent attention on exploring substitutes to non-renewable resources and highlighting the reduced environmental impacts, researches are progressively being focused at the development of biodegradable materials from biocomposite and biopolymer-based materials. This re Read More

Background: Blue is a color not often present in food. Even so, it is especially attractive to children. Today, most blue coloring agents used by the food industry are synthetic. With increasing health issues concern by the scientific community and the general population, there is a trend to look for natural alternatives to most synthetic products. There only exist few natural blue colorants, which are presented in a literature surve Read More

Background: Aristolochic acids are chemically linked to nitrophenanthrene carboxylic acids which are found in aristolochia plants. These compounds are intrinsically carcinogenic, while they have been used in traditional medicine from a long time ago. Despite the beneficial effects of herbals for treating some diseases, they possess some side effects. Methods: Therefore, the development of a sensitive and selective procedure for Read More

Background: TLC bioautography is a hyphenated technique combining planar chromatographic separation and in situ biological activity detection. This coupled method has been receiving much attention in screening bio-active natural products because of its properties of being simple, rapid, inexpensive, and effective. Methods: The recent progress in the development of method of TLC bioautography for detecting antimicrobi Read More

Background: Multiple Sclerosis (MS) involves an immune-mediated response in which body’s immune system destructs the protective sheath (myelin). Part of the known MS biomarkers are discovered in cerebrospinal fluid like oligoclonal lgG (OCGB), and also in blood like myelin Oligodendrocyte Glycoprotein (MOG). The conventional MS diagnostic methods often fail to detect the disease in early stages such as Cli Read More

Background: Bisphenol A (BPA) is considered one of the most common chemicals that could cause environmental endocrine disrupting. Therefore, there is an increasing demand for simple, rapid and sensitive methods for BPA detection that result from BPA leaching into foods and beverages from storage containers. Herein, a simple laccase electrochemical biosensor was developed for the determination of BPA based on Scre Read More

Background: The investigation of human bones unearthed from necropolises is a useful tool to enhance our knowledge about ancient cultures. In the present study, the possibility of using the activation energy (EA) values of thermogravimetric degradation processes coupled with exploratory analysis methods in order to investigate human remains, has been tested. Methods: Several human bones from four distinct necropolise Read More

Background: Dichromate (Cr2O72-) ion is one of the carcinogenic and toxic spices in environment which can easily contaminate the environment due to its high solubility in water. Therefore, a lot of attention has been focused on the detection of Cr2O72- with high sensitivity and selectivity. Methods: In present work, nitrogen-rich precursor was used for synthesizing graphitic carbon nitride (g-C3N4) nanostructures through h Read More

Background: Ticagrelor is a highly recommended new antiplatelet agent for the treatment of patients with acute coronary syndrome at moderate or high ischemic risk. There is a real need for rapid and accurate analytical methods for ticagrelor determination in biological fluids for pharmacokinetic studies. In this study, a sensitive and specific LC-MS method was developed and validated for quantification of ticagrelo Read More

Background: Type 2 diabetes mellitus is an expanding health problem. Binary antidiabetic combinations of Metformin Hydrochloride (MET) with either Saxagliptin Hydrochloride (SAX), or Dapagliflozin (DAP) are widely used. Review of the literature revealed that no single HPTLC method has been reported for the simultaneous determination of MET, SAX, and DAP allowing the determination of binary mixtures of any two of th Read More

Background: Iron is an essential transition metal which is indispensable for life processes like oxygen transport and metabolism, electron transfer etc. However, misregulated iron is responsible for disease like anemia, hemochromatosis, Alzheimer’s and Parkinson’s disease. In order to encounter these diseases, a better understanding is needed of its role in misregulation. Fluorescent iron sensors could help provide this i Read More

Background: Trimethylamine (TMA) is a nitrogenous base aliphatic organic compound accounting for the odor of rotten fish and it is used as an indicator for analyzing the quality of fish products. Introduction: Extraction procedures and analytical methods including colorimetric and Gas- Chromatography (GC) can quantify the TMA contents of fish products after pre-treatment with basic solutions. However, the extraction Read More

Background: Aluminum Al(III) is the most significant metal in the earth's crust to which humans are frequently exposed and has several industrial applications. On the other hand, Al (III) has high potential toxic impacts on some human pathologies like Parkinson and Alzheimer's disease. So, it is very important to monitor and determine the trace level of Al (III) in various environmental and biological samples. Objective: In the pre Read More

Background: An Ionic Liquid-based based Dispersive Liquid-Liquid Microextraction (IL-DLLME) method was not applied to preconcentration and determination of bilirubin. Ionic Liquids (ILs) are new chemical compounds. In recent years, Ionic Liquids (ILs) have been employed as alternative solvents to toxic organic solvents. Due to these perfect properties, ILs have already been applied in many analytical extraction processe Read More

Background: Amygdalin is a natural compound known for curing cancer. It is seen in several plants including in bitter almonds, apricots, peaches, apples, and plum seeds (kernels). Amygdalin is a toxic molecule containing a nitrile group, due to which toxic cyanide anion releases by the action of a β-glucosidase. The consumption of amygdalin may lead to cyanide poisoning in the human body. Therefore, for the first time, this w Read More