Current Analytical Chemistry - Volume 16, Issue 3, 2020

Introduction: A molecular imprinting is one of the fascinating modification methods that employ molecules as targets to create geometric cavities for recognition of targets in the polymeric matrix. This method provides a broad versatility to imprint target molecules with different size, three-dimensional structure and physicochemical features. In contrast to the complex and timeconsuming laboratory surface modification pro Read More

Background: Sartans are mostly used as a part of combination with additional medicines in the therapy of essencial hypertension. Preferred combinations are ARB and thiazide diuretics (Hydrochlorothiazide (HCT) and Chlorthalidone (CHL)) or ARB and calcium antagonists. The number of sartans mostly prescribed by specialists is only seven - Candesartan (CDS), Eprosartan (EPS), Irbesartan (IBS), Losartan (LOS), Olmesart Read More

Background: This work reports a green analytical method for the determination of organic environmental pollutants using nano-liquid chromatography with a self-made column for rapid, sensitive, inexpensive and efficient analysis of BTX pollutants in water. The applications of monolithic nanoscale columns for quantitative analysis of environmental real samples are very limited in the literature. Methods: A capill Read More

Background: Hydrogen (H) and Carbon (C) are major elements that occur in various materials, including organic matter. The identification and analysis of C and H are necessary for several fields. LIBS is an excellent method for such analysis because it is rapid, and can be conducted remotely. The technique has been employed for the analysis of H in zircaloy metals. However, few studies on the emission characteristic Read More

Background: Diclofenac (DCF) is an important widely used non-steroidal antiinflammatory drug. Disposal of expired formulation, excretion from administered dose, the poor performance of sewage treatment process, contributes to its frequent detection in environment. Analysis of DCF in environmental sample requires time consuming pretreatment, extraction steps. Though, UV absorption analysis of DCF is simple but spe Read More

Objective: Ten racemic 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones were separated by liquid chromatography on Chiralcel®OD-H column containing cellulose tris(3, 5-dimethylphenylcarbamate). Methods: The enantioseparation was carried out using Chiralcel®OD-H polysaccharide-type chiral stationary phase to resolve such enantiomers under normal-phase mode. Results: Complete Read More

Background: Pesticides are increasingly used in agriculture and households, but they are also considered a major pollutant to the environment. Carbofuran (CAR; 2,3-dihydro-2,2- dimethylbenzofuran-7-yl methylcarbamate) is a widely used pesticide due to its effectiveness on soybean aphids. Objectives: A simple and green method was suggested for the extraction and determination of CAR in different matrices. Methods: A dia Read More

Background: This manuscript focuses on Novel multivariate UV-chemometric method and HPLC-QbD method for simultaneous determination of Vardenafil (VR) and Dapoxetine (DP) in active pharmaceutical ingredient and their marketed formulation. To the best of our knowledge, there is no literature data on multivariate methods for the same. Methods: The spectrophotometric data were processed by CLS, PCR, PLS and MLR Read More

Background: The first highly sensitive, rapid and specific green microemulsion liquid chromatographic (MELC) method was established for the simultaneous estimation of fluticasone propionate (FLU) and azelastine HCl (AZL) in the presence of their pharmaceutical dosage form additives (phenylethyl alcohol (PEA) and benzalkonium chloride (BNZ)). Methods: The separation was performed on a C18 column using (o/w) micr Read More

Background: Gold nanoparticles (Au NPs) are normally prepared using standard gold (III) trichloride which is much expensive and irritant. This work is aimed at demonstrating simple and low-cost synthesis of Au NPs from the reused traditional gold leaf which is cost-free and less toxic. Methods: The reused gold leaf was donated by the local temple. It was digested and used as the precursor for the preparation of the Au NPs by Tu Read More

Background: Paederia scandens (Lour.) Merrill, belonging to the Rubiaceae family, was one of the Traditional Chinese Medicines that has been generally used to treat aches and pains, inflammation, bacillary dysentery, piles and rheumatic arthritis. The four iridoid glycosides that Paederosidic acid, Paederoside, Paederosidic acid methyl ester, and Asperuloside from Paederia scandens are considered to be the mai Read More

Background: Graphene quantum dots (GQD) is a new member of carbon nanomaterial that has attracted increasing attention owing to its better chemical inertness, low cytotoxicity, large specific surface area, cheap cost, suitable conductivity and excellent biocompatibility. Methods: Electrochemical behaviors of this modified electrode were studied by cyclic voltammetry and electrochemical impedance spectroscopy. Read More

Background: Biocompatible and easily available immobilization matrix is vital for the construction of enzyme-based biosensor. Methods: Reed membrane was selected as a novel immobilization matrix to construct an optical phenol biosensor. Tyrosinase from mushroom was immobilized in a reed membrane using glutaraldehyde as a cross-linker. The detection scheme was based on the measurement of the color intensity of Read More

Background: Punica granatum L. (pomegranate) is one of the oldest edible fruits used for the treatment of countless diseases. The bioactivity of this fruit is mainly related to tannins, especially elagitannins. P.granatum fruit peel dried extracts (PPDEs) are widely marketed today and the lack of accessible quality control methods is a key to the variable and questionable quality of these products. Objective: To develop a miniaturiz Read More

Background: The magnetic nanocomposites are very important as a reusable sorbents for the extraction of Cd(II) and other toxic metals from water samples. Methods: The Ag/MgO@Fe3O4 nanocomposite was synthesized by the coprecipitation method and characterized by the XRD, EDX, SEM, UV-vis spectroscopy and FTIR. This nanocomposite was used to extract Cd(II) from water samples prior to its quantitative analysis Read More

Background: Recently, Derris scandens, a Thai herbal medicine with anti-inflammatory activity, is widely used as beverage and supplementary food. When the traditional medicine is a choice for health therapy, the simple and reliable equipment is required to control the suitable consuming amount of the active component. Objective: To develop the electrochemical sensor for genistein determination in Derris scandens with h Read More