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- Volume 13, Issue 5, 2023
Natural Products Journal, The - Volume 13, Issue 5, 2023
Volume 13, Issue 5, 2023
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Neuroprotection of Multitargeted Phytochemicals against Alzheimer: A Desperate Need from Nature
Authors: Ashwani K. Dhingra and Bhawna ChopraBackground: Alzheimer’s disease (AD) is an incurable neurodegenerative disorder associated with dementia which leads to the alteration in the psychological and physiological functioning of the individual. From antiquity, medicinal plants serve as important sources of bioactive phytochemicals representing tremendous therapeutic potential. The unavoidable adverse effects associated with synthetic compounds t Read More
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Biomedical Applications of Agar and its Composites: A Mini-Review
Authors: Greeshma Surendran and Atul P. SherjeAgar is a flexible biopolymer that forms jelly like consistency when mixed with water. It is extracted from seaweeds by treatment with alkali and can also be synthesized from fructose-6- phosphate. Agar and its composites were found to have applications in drug delivery, wound healing, tumour therapy and hyperthermia treatment. Agar gel formulations have been used for ultrasound imaging since it has the ability to scatter sou Read More
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Chemotherapeutic Effects of Boswellic Acid Against Human Glioblastoma Multiform: A Comprehensive Review
Background: Glioblastoma multiform (GBM) is a malignant subgroup of gliomas. Due to the natural resistance of GBM cells to radio-and chemotherapy usually, recurrence occurs 6-9 months after diagnosis. Objective: This paper reviewed the beneficial effects of Boswellic acid (BA) in adjacent therapy for GBM, based on its possible molecular mechanisms. Methods: In this review paper, all papers indexed in scientific da Read More
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A Review of Phytoconstituents as Antibacterial Agents
Authors: Gunjan Bisht, Ankit K. Singh, Adarsh Kumar and Pradeep KumarBackground bacteria cause various infectious diseases and cause millions of deaths each year. Bacteria are broadly classified based on the phenotypic and genotypic systems. Bacteria cause resistance mainly by Plasmids, Inactivation of antibiotics, Target site modification, Preventing drug uptake, Efflux pumps, and Biofilm. Plants have been used for thousands of years for their medicinal properties to treat various dise Read More
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Novel Delivery Technologies: Triggering the Biopharmaceutical Potential of Boswellic Acids
Boswellic acids are a series of pentacyclic triterpenes derived from the gum resin of Boswellia genus, mostly from Boswellia serrata Roxb. (Burseraceae) tree commonly known as Indian Frankincense or salai guggul and traditionally used as an anti-inflammatory agent. It acts by inhibiting 5-Lipoxygenase, C3-convertase, cyclooxygenase, preferably COX-1, Human Leukocyte Elastase, NF- ΚB expression, Topoisome Read More
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Natural Carbohydrates-based Nanoparticles: A Review of Pharmaceutical Applications
Authors: Karan Kumar, Sheetu Wadhwa, Arun Sharma, Gurvinder Singh and Rajesh KumarCarbohydrates are the most common biopolymers with the capability to construct supramolecular structures. For biomedical purposes, a variety of carbohydrate-based nanoparticles have been used. Basic monosaccharides or disaccharides, along with sophisticated polymeric systems, are used to create these structures. The shape and properties of these materials can be modified using chemical alterations. Carbohydrates-base Read More
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Effect of Curcumin on Oxidative Stress, Inflammatory Response and Kidney Biochemical Parameters Among Kidney Disease Patients: A Systematic Review
Background: Chronic kidney disease (CKD) and end-stage renal diseases have high global morbidity and mortality. Objective: We aimed to investigate the antioxidant and anti-inflammatory properties of curcumin and its impact on kidney biochemical parameters associated with kidney disease among CKD and hemodialysis (HD) patients. Methods: The intended keywords were used in the literature search. Clinical trial stu Read More
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Antioxidant and Anti-inflammatory Activities Mediate the Radioprotective Effect of Trianthema portulacastrum L. Extracts
Background: Ionizing radiation (IR) generates reactive oxygen species (ROS), which leads to oxidative stress that often leads to inflammatory responses in organisms. Objective: Trianthema portulacastrum L., a plant commonly growing in India, is rich in antioxidant phytochemicals. This is responsible for scavenging free radicals and may provide radioprotective and anti-inflammatory effects in response to ionizing radiation. Read More
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