Natural Products Journal, The - Volume 12, Issue 6, 2022

Since the initial outbreak in December 2019, the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 3 million deaths worldwide. There is an urgent need for developing a potential therapy against SARS-CoV-2. Exploring the potentials of phytochemicals towards inhibition of SARS-CoV-2 proteins remains of significant scientific interest. The therapeutic values o Read More

Background: Medicinal plants have been used in medicine for the treatment of numerous diseases due to their medicinal properties and pharmacological activities. The popularity of herbal- based drugs in the health sector has been increasing due to patient compliance and cost-effectiveness. Herbal drugs derived from plant and animal sources have been used in the Ayurvedic, Homeopathic, and Naturopathic sy Read More

The Amazon rainforest has wide and unique biodiversity, which is an important source of natural products for the development of drugs. Neglected tropical diseases (NTDs) represent a major health problem as they affect over 1 billion people, especially vulnerable populations living in tropical and subtropical regions. Currently available drugs are generally inadequate for the majority of these diseases, thus, there is an urgent n Read More

Background: Clusia nemorosa, popularly known as pororoca, is used in folk medicine to treat inflammation. Objective: The current study was conducted to isolate and identify bioactive compounds from C. nemorosa fruits and to investigate their antimicrobial and antioxidant activities. Methods: The isolation and structural elucidation of the substances were carried out by usual chromatographic techniques and spectros Read More

Background: The Coussapoa genus (Urticaceae, tribe Cecropieae) contains 50 species mainly distributed throughout the Neotropical region. Although some genera belonging to the Cecropieae tribe have been well-assessed, the chemical profile of Coussapoa members has not yet been investigated. Objective: In this context, the aim of the present study was to characterize phenolic substances present in a methanol extr Read More

Background: The composition and bioactivity of natural plant extract strongly depend on the extraction technique employed. Clinacanthus nutans Lindau (C. nutans) is a well-known medicinal plant in South-East Asia that has been traditionally used for the treatment of various diseases. Several conventional methods have been using for the extraction of bioactive compounds from C. nutans. However, extraction of fatty acids usi Read More

Aim: Herein, we determined the anti-amoebic properties of propolis collected from different regions in Iran against Naegleria fowleri and Balamuthia mandrillaris. Background: Natural products remain a valuable source of compounds that are biologically active. Approximately one-third of well-known therapeutic drugs worldwide are derived from natural products. Objectives: Considering the use of propolis in folk m Read More

Background: Saline stress is an important environmental factor that limits the productivity of numerous agricultural crops, such as onion (Allium cepa L.), a vegetable present in gardens and used in various ways. Pulegone has been identified as a component that has a large number of biological functions. Objective: The aim of this study was to investigate the effect of pulegone (100 and 500 μg/mL) on the morphological Read More

Aim: Spirulina is a microalga that is widely used as a food supplement and is regarded as having performance-enhancing and health-promoting properties. We conducted a preliminary evaluation of the possible anti-depressant, anti-anxiety, pro-socialization and cognition-enhancing effects of Spirulina in mouse models. Methods: Sixty male BalbC mice aged 3 weeks were administered with phycocyanin-rich Spirulina extract [PR Read More

Background: Ferns are underestimated as medicinal plants and their use in traditional medicine is limited despite their diversity. Most of the research on their healing properties and phytochemical composition related to their biological activity has been focused on the secondary metabolites synthesized by ferns. Objective: In this study, we aimed to make an in-depth chemical characterization of three ferns widely Read More