Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Natural Products Journal, The
  4. Volume 15, Issue 1
  5. Article
Volume 15, Issue 1
  • ISSN: 2210-3155
  • E-ISSN: 2210-3163

Abstract

Background

, popularly known as “espinheira santa”, is a plant native to southern Brazil and is widely used in popular therapeutics to treat gastric disturbances. is commonly adulterated, intentionally or not, with the plant species and due to the morphological similarity of their leaves.

Objective

The aim of this review was to search for changes in the quality control method of products to support the correct identification of the botanical species. In addition, the search covered clinical studies, patents, and registered products of herbal medicines based on .

Methods

This study is an integrative literature review that was developed using databases, indexed articles, and books. The bibliographic searches were performed using Scopus®, SciFinder®, Scielo®, and Science Direct®. Patent documents and herbal medicines containing were searched in the INPI and WIPO databases.

Results

The pharmacological activities of , the main chemical constituents, and leaf morpho-anatomical characteristics of spp., , and were summarized. The results also demonstrated herbal medicines based on marketed in Brazil, patents in Brazil, and patents in the world market.

Conclusion

Quality control for the species presents opportunities for improvement. The officially recommended method presents weaknesses concerning species identification. Other chemical markers should be included in the chromatographic analyses. There are seven medicines with valid registrations in Brazil. Furthermore, patents filed in Brazil and at WIPO demonstrate that has therapeutic potential in the world market.

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/npj/10.2174/0122103155283762240213072144
2025-01-01
2025-05-12

  • From This Site

    /content/journals/npj/10.2174/0122103155283762240213072144
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. Fonseca da SilvaR.C.M.V.A. BoeingT. Bolda MarianoL.N. SomensiL.B. da SilvaL.M. de SouzaP. The pathophysiology of acute gastric ulcer development in normotensive and hypertensive rats: A comparative study.Eur. J. Pharmacol.202088717346910.1016/j.ejphar.2020.17346932800807
     [Google Scholar]
  2. Da Rosa SousaS. de Oliveira BernardoG. FaracoA.J. de Oliveira BernardoC. Perfil epidemiológico dos pacientes diagnosticados com úlcera gástrica e/ou duodenal em dois serviços de referência do extremo sul catarinense no período de um ano.Arq Catarin Med2017465969
     [Google Scholar]
  3. BragaM.P. SilvaC.D.B. AdamsA.I.H. Inibidores da bomba de prótons: Revisão E análise farmacoeconômica.Saúde2012372193210.5902/223658342963
     [Google Scholar]
  4. WangA. YerxaJ. AgarwalS. TurnerM.C. SchroderV. YoungwirthL.M. Lagoo-DeenadayalanS. PappasT.N. Surgical management of peptic ulcer disease.Curr. Probl. Surg.202057210072810.1016/j.cpsurg.2019.10072832138833
     [Google Scholar]
  5. BiralL. SimmonsM.P. SmidtE.C. TembrockL.R. BolsonM. ArcherR.H. LombardiJ.A. Systematics of new world Maytenus (Celastraceae) and a new delimitation of the genus.Syst. Bot.201742468069310.1600/036364417X696456
     [Google Scholar]
  6. Tropicos database: Missouri Botanical Garden, version 3.4.2.Available from: https://www.tropicos.org/ (Accessed 21 Dec 2023).
  7. Plants of the World Online databe: Royal Botanic Gardens.Available from: https://powo.science.kew.org/ (Accessed 21 Dec 2023).
  8. AlbertonM.D. FalkenbergD.B. FalkenbergM.B. Análise cromatográfica de fitoterápicos a base de espinheira-santa] (Maytenus ilicifolia).Rev. Bras. Farmacogn.200212111310.1590/S0102‑695X2002000300006
     [Google Scholar]
  9. VelosoC.C. SoaresG.L. PerezA.C. RodriguesV.G. SilvaF.C. Pharmacological potential of Maytenus species and isolated constituents, especially tingenone, for treatment of painful inflammatory diseases.Rev. Bras. Farmacogn.201727453354010.1016/j.bjp.2017.02.006
     [Google Scholar]
  10. Santos-OliveiraR. Coulaud-CunhaS. ColaçoW. Revisão da Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribuição ao estudo das propriedades farmacológicas.Rev. Bras. Farmacogn.2009192b65065910.1590/S0102‑695X2009000400025
     [Google Scholar]
  11. JesusW.M.M. CunhaT.N. Estudo das propriedades farmacológicas da espinheira-santa (Maytenus ilicifolia Mart. ex Reissek) e de duas espécies adulterantes.Rev Saude Desenvolv201222046
     [Google Scholar]
  12. SchindlerM.S.Z. CalistoJ.F.F. MarinsK. RegginatoA. MezzomoH. ZanattaA.P. RadunzA.L. MariotM.P. Dal MagroJ. ZanattaL. Characterization of the chemical profile and the effects of ethanolic extracts of Maytenus ilicifolia Mart. ex Reissek on glucose metabolism in normal hyperglycemic rats.J. Ethnopharmacol.202127611417310.1016/j.jep.2021.11417333932519
     [Google Scholar]
  13. GeoczeS. VilelaM.P. ChavesB.D. FerrariA.P. ArliniE.A. Tratamento de pacientes portadores de dispepsia alta ou de úlcera péptica com preparações de Espinheira-santa (Maytenus ilicifolia).In: Estudo de ação antiúlcera gástrica de plantas brasileiras (Maytenus ilicifolia” espinheira-santa” e outras).BrazilCEME19887587
     [Google Scholar]
  14. RENISUS Relação Nacional de Plantas Medicinais de Interesse ao SUS. Espécies vegetais.2009Available from: https://bvsms.saude.gov.br/bvs/sus/pdf/marco/ms_relacao_plantas_medicinais_sus_0603.pdf
    [Google Scholar]
  15. Memento Fitoterápico - Farmacopeia Brasileira.1st edBrasiliaANVISA2016
     [Google Scholar]
  16. Brazil. Formulário de Fitoterápicos da Farmacopeia Brasileira.1st edBrasiliaAnvisa2011
     [Google Scholar]
  17. Formulário de Fitoterápicos da Farmacopeia Brasileira.2nd edBrasiliaAnvisa2021
     [Google Scholar]
  18. Brazil. Relação Nacional de Medicamentos Essenciais: Rename 2020.BrasiliaMinistry of Health2020
     [Google Scholar]
  19. PradoM.A.S.A. MatsuokJ.T. GiottoA.C. Importância das Farmácias Vivas no âmbito da produção dos medicamentos fitoterápicos.2018Available from: https://revistasfacesa.senaaires.com.br/index.php/iniciacao-cientifica/article/view/45
    [Google Scholar]
  20. Provides for the registration of herbal medicines and the registration and notification of traditional herbal products. Resolution of the Collegiate Board -RDC N° 26, 13 May 2014.BrasiliaMinistry of Health2014
     [Google Scholar]
  21. Brazilian Pharmacopoeia2019Available from: https://www.gov.br/anvisa/pt-br/assuntos/farmacopeia/farmacopeia-brasileira/arquivos/8025json-file-1
  22. ErcoleF.F. MeloL.S.D. AlcoforadoC.L.G.C. Revisão integrativa versus revisão sistemática. 2014.;Available from: https://www.dx.doi.org/10.5935/1415-2762.20140001
    [Google Scholar]
  23. PaivaM.R.F. ParenteJ.R.F. BrandãoI.R. QueirozA.H.B. Metodologias ativas de ensino-aprendizagem: Revisão integrativa.2016Available from: https://sanare.emnuvens.com.br/sanare/article/view/1049
    [Google Scholar]
  24. Bibliographic Database.Amsterdam, NetherlandsElsevier2021
     [Google Scholar]
  25. SciFinder. Bibliographic database and search site, chemical abstracts service, columbus. Available from: http://scifinder.cas.org/ (Accessed 05 Aug 2022).
  26. Scientific Electronic Library Online, São Paulo. Available from: https://scielo.org/ (Accessed 15 Oct 2021).
  27. Bibliographic Database and Search Site.Available from: https://www.sciencedirect.com/ (Accessed 01 Aug 2022).
  28. The Plant List, version 1.1.Available from: http://www.theplantlist.org/tpl1.1/record/kew-2360158 (Accessed 06 Aug 2022).
  29. Datavisa ANVISA Website, Brazil, Ministry of Health.Available from: https://consultas.anvisa.gov.br/#/medicamentos/ (Accessed 25 Jan 2022).
  30. National Institute of Industrial Property (INPI).Available from: https://busca.inpi.gov.br/pePI/jsp/patentes/PatenteSearchBasico.jsp (Accessed 16 Sept 2021).
  31. World Intellectual Property Organization (WIPO)Available from: https://patentscope.wipo.int/search/en/search.jsf (Accessed 18 Oct 2021).
  32. RossatoA.E. PieriniM.D.M. AmaralP.D.A. SantosR.R.D. Citadini-ZanetteV. Fitoterapia racional: Aspectos taxonômicos, agroecológicos, etnobotânicos e terapêuticos.1st edFlorianópolisDIOESC2012Vol. 1
     [Google Scholar]
  33. AlmeidaC. BarbieriR.L. RibeiroM.V. LopesC.V. HeckR.M. Espinheira-santa (Maytenus ilicifolia Mart. ex Reiss.): Saber de erveiros e feirantes em Pelotas (RS).Rev. Bras. Plantas Med.2015174suppl. 172272910.1590/1983‑084X/14_003
     [Google Scholar]
  34. MariotM.P. BarbieriR.L. Divergência genética entre acessos de espinheira-santa (Maytenus ilicifolia Mart. ex Reissek e M. aquifolium Mart.) com base em caracteres morfológicos e fisiológicos.Rev. Bras. Plantas Med.201012324324910.1590/S1516‑05722010000300001
     [Google Scholar]
  35. FonsecaA.P.N.D. SilvaG.D.F. CarvalhoJ.J. SalazarG.D.C.M. DuarteL.P. SilvaR.P. JorgeR.M. TagliatiC.A. ZaniC.L. AlvesT.M.A. PeresV. Vieira FilhoS.A. Estudo fitoquímico do decocto das folhas de Maytenus truncata Reissek e avaliação das atividades antinociceptiva, antiedematogênica e antiulcerogênica de extratos do decocto.Quim. Nova200730484284710.1590/S0100‑40422007000400016
     [Google Scholar]
  36. FloraC.N.C. Maytenus robusta in: Lista vermelha da flora brasileira, version 2012.2 Centro Nacional de Conservação da Flora.Available from: http://cncflora.jbrj.gov.br/portal/pt-br/profile/ (Accessed 21 Oct 2021).
     [Google Scholar]
  37. SouzaV.C. LorenziH. Botânica sistemática: Guia ilustrado para identificação das famílias de Fanerógamas nativas e exóticas no Brasil.Centro Nacional de Conservação da Flora2012
     [Google Scholar]
  38. CoelhoR.G. Estudo químico de Zollernia ilicifolia (Fabaceae), Wilbrandia ebracteata (Cucurbitaceae) e Caesalpinia ferrea (Caesalpiniaceae).. Thesis, Postgraduate Program in Chemistry, Unesp, Araraquara.,2004
     [Google Scholar]
  39. Pavan-FruehaufS. Plantas medicinais de Mata Atlântica: manejo sustentado e amostragem.São PauloAnnablume2000
     [Google Scholar]
  40. PereiraP.A. Chemical investigation of Sorocea bonplandii (Baillon) Burger, Lanjouw and Boer (Moraceae).. Dissertation, Postgraduate Program in Pharmacy, Federal University of Santa Catarina: Florianópolis.,2005
     [Google Scholar]
  41. RuschelA.R. NodariR.O. Colheita foliar da cancorosa [Sorocea bonplandii (Baill.) Burg., Lanj. & W. Boer]: Uma espinheira-santa da Mata Atlântica.Rev Bras Pl Med20081044354
     [Google Scholar]
  42. AlbertonM.D. Investigação fitoquímica de Zollernia ilicifolia (Brongniart) Vogel (Fabaceae): Contribuição ao controle de qualidade de espinheira-santa (Maytenus spp.).. Dissertation Universidade Federal de Santa Catarina, Florianópolis, Brazil.2001
     [Google Scholar]
  43. AliS. RechK.S. BadshahG. SoaresF.L.F. BarisonA. 1H HR-MAS NMR-Based metabolomic fingerprinting to distinguish morphological similarities and metabolic profiles of Maytenus ilicifolia, a Brazilian medicinal plant.J. Nat. Prod.20218461707171410.1021/acs.jnatprod.0c0109434110831
     [Google Scholar]
  44. do AmaralF.M. MonteiroS.S.R. FernandesT. TeixeiraD.F. LucchettiL. JacobS.C. de PaivaS.R. JoffilyA. Pharmacobotanical characterization of Monteverdia ilicifolia (Mart. ex Reiss.) Biral leaves and its adulterants sold as medicinal tea in Brazil: A contribution to quality control.Bol. Latinoam. Caribe Plantas Med. Aromat.202120438639310.37360/blacpma.21.20.4.28
     [Google Scholar]
  45. SantosG.U.C.A. FreitasE.A. GomesL.C.A. GoudardM.J.A. GuimarãesF.G. SilvaB.R.G. GomesJ.F. SilvaY.C. GonçalvesP.R. CalladoC.H. Identificação anatômica de amostras comercializadas como espinheira-santa na Região Metropolitana do Rio de Janeiro.Paubrasilia20214e0064e006410.33447/paubrasilia.2021.e0064
     [Google Scholar]
  46. Soares GarciaJ. OliveiraC.J.F. Jr Espinheira-santa: Do extrativismo à produção sustentável.Nativa 20219440141210.31413/nativa.v9i4.12222
     [Google Scholar]
  47. MachadoAV SantosM Comparative leaf morpho-anatomy of species known as espinheira-santa: Maytenus ilicifolia (Celastraceae), Sorocea bonplandii (Moraceae) and Zollernia ilicifolia (Leguminosae). INSULA Rev. Botany.,2004, 33, 01.
     [Google Scholar]
  48. PederneirasL.C. RibeiroJ.E.L.S. MattosL. Sorocea in flora do Brasil. Jardim botânico do rio de janeiro.2020Available from: https://floradobrasil2020.jbrj.gov.br/FB31440 (Accessed 18 Aug 2022).
  49. PereiraA.M.S. JanuárioA.H. QueirozM.E.E. BiondoR. FrançaS.C. Evaluation of Maytenus aquifolia Mart. and Maytenus ilicifolia Mart. chemotypes for tannins, total phenols and triterpenes.Rev Bras Pl Med2005811317
     [Google Scholar]
  50. SoaresL.A.L. OliveiraA.L. OrtegaG.G. PetrovickP.R. Development and validation of a LC-method for determination of catechin and epicatechin in aqueous extractives from leaves of Maytenus ilicifolia.J. Pharm. Biomed. Anal.200436478779010.1016/j.jpba.2004.08.02915533671
     [Google Scholar]
  51. GamesR.A.T. Contribuição ao controle de qualidade de Maytenus ilicifolia Mart. ex Reiss. - Celastraceae, Disssertation Professional Master’s Program in Pharmacy.São PauloUNIBAN2010
     [Google Scholar]
  52. DutraR.C. CamposM.M. SantosA.R.S. CalixtoJ.B. Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives.Pharmacol. Res.201611242910.1016/j.phrs.2016.01.02126812486
     [Google Scholar]
  53. ChedierL.M. Maytenus ilicifolia (Scharad.) Planch. In: Coletânea científica de plantas de uso medicinal; Amaral, A.C.F.; Simões, E.V.; Ferreira, J.L.P., Eds.; Fiocruz: Rio de Janeiro2005125146
     [Google Scholar]
  54. BaggioC.H. FreitasC.S. MayerB. dos SantosA.C. TwardowschyA. PotrichF.B. CiprianiT.R. de SouzaL.M. SassakiG.L. IacominiM. MarquesM.C.A. Mesia-VelaS. Muscarinic-dependent inhibition of gastric emptying and intestinal motility by fractions of Maytenus ilicifolia Mart ex.Reissek. J. Ethnopharmacol.2009123338539110.1016/j.jep.2009.03.03719501270
     [Google Scholar]
  55. LealA.F.V.B. Ensaio de dissolução de fitoterápicos contendo Maytenus ilicifolia Marth ex Reiss (Celastraceae): Validação de métodos para quantificação de catequina e epicatequina.. Dissertation. Universidade Federal de Goiás, Goiânia, Brazil.,2010
     [Google Scholar]
  56. LeiteJ.P.V. RastrelliL. RomussiG. OliveiraA.B. VilegasJ.H.Y. VilegasW. PizzaC. Isolation and HPLC quantitative analysis of flavonoid glycosides from Brazilian beverages (Maytenus ilicifolia and M. aquifolium).J. Agric. Food Chem.20014983796380110.1021/jf010294n11513669
     [Google Scholar]
  57. FerreraT.S. HeldweinA.B. Dos SantosC.O. SomavillaJ.C. SautterC.K. Substâncias fenólicas, flavonoides e capacidade antioxidante em erveiras sob diferentes coberturas do solo e sombreamentos.Rev. Bras. Plantas Med.2016182suppl. 158859610.1590/1983‑084x/15_197
     [Google Scholar]
  58. RadomskiM.I. WisniewskiC. CurcioG.R. RachwalM.G. SantosC.A.M. Caracterização de ambientes de ocorrência natural e sua influência sobre o peso específico e o teor de polifenóis totais de folhas de espinheira-santa (Maytenus ilicifolia Mart.).Rev Bras Pl Med2004623643
     [Google Scholar]
  59. MorschelC.F. MafraD. EduardoJ.C.C. Inibidores da bomba de protons e sua relação com a doença renal.J. Bras. Nefrol.2018403130610.1590/2175‑8239‑jbn‑2018‑002130010692
     [Google Scholar]
  60. TibertiL.A. YariwakeJ.H. NdjokoK. HostettmannK. Identification of flavonols in leaves of Maytenus ilicifolia and M. aquifolium (Celastraceae) by LC/UV/MS analysis.J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.20078461-237838410.1016/j.jchromb.2006.09.01417011840
     [Google Scholar]
  61. de SouzaL.M. CiprianiT.R. IacominiM. GorinP.A.J. SassakiG.L. HPLC/ESI-MS and NMR analysis of flavonoids and tannins in bioactive extract from leaves of Maytenus ilicifolia.J. Pharm. Biomed. Anal.2008471596710.1016/j.jpba.2007.12.00818215490
     [Google Scholar]
  62. LopesG.C. BlainskiA. SantosP.V.P. DiciaulaM.C. MelloJ.C.P. Development and validation of an HPLC method for the determination of epicatechin in Maytenus ilicifolia (Schrad.) Planch.Celastraceae. Rev. Bras. Farmacogn.201020578178810.1590/S0102‑695X2010005000024
     [Google Scholar]
  63. DiagoneC.A. ColomboR. LançasF.M. YariwakeJ.H. CZE/PAD and HPLC-UV/PAD profile of flavonoids from Maytenus aquifolium and Maytenus ilicifolia “espinheira santa” leaves extracts.Chromatogr. Res. Int.201220121710.1155/2012/691509
     [Google Scholar]
  64. SáR.R. MatosR.A. SilvaV.C. da Cruz CaldasJ. da Silva SauthierM.C. dos SantosW.N.L. MagalhãesH.I.F. de Freitas Santos JúniorA. Determination of bioactive phenolics in herbal medicines containing Cynara scolymus, Maytenus ilicifolia Mart ex Reiss and Ptychopetalum uncinatum by HPLC-DAD.Microchem. J.2017135101510.1016/j.microc.2017.07.009
     [Google Scholar]
  65. VilegasJ.H.Y. LançasF.M. WautersJ.N. AngenotL. Characterization of adulterations of “espinheira santa” (Maytenus ilicifolia M. and M. aquifolium M., Celastraceae) hydroalcoholic extracts with Sorocea bonplandii (Moraceae) by high-performance thin layer chromatography.Phytochem. Anal.1998926326610.1002/(SICI)1099‑1565(199811/12)9:6<263::AID‑PCA415>3.0.CO;2‑N
     [Google Scholar]
  66. VilegasJ.H.Y. LançasF.M. CerviA.C. High resolution gas chromatography analysis of ‘espinheira santa’ (Maytenus ilicifolia and M. aquifolium): Analysis of crude drug adulterations.Phytother. Res.19948424124410.1002/ptr.2650080411
     [Google Scholar]
  67. NossackA.C. VasconcelosE.C. VilegasJ.H.Y. LançasF.M. RoqueN.F. Quantitative analysis of triterpenes friedelan-3-β-ol and friedelin in Maytenus aquifolium by high-resolution gas chromatography and high-temperature capillary gas chromatography.Phytochem. Anal.20001124324610.1002/1099‑1565(200007/08)11:4<243::AID‑PCA520>3.0.CO;2‑Q
     [Google Scholar]
  68. VistubaJ.P. PiovezanM. PizzolattiM.G. RebeloA.M. AzevedoM.S. VitaliL. CostaA.C.O. Amadeu MickeG. Increasing the instrumental throughput of gas chromatography method using multiple injections in a single experimental run: Application in determination of friedelan-3-ol and friedelin in Maytenus ilicifolia.J. Chromatogr. A2013127415916410.1016/j.chroma.2012.11.08723276648
     [Google Scholar]
  69. NossackA.C. CeleghiniR.M.S. LançasF.M. YariwakeJ.H. HPLC-UV and LC-MS analysis of quinonemethides triterpenes in hydroalcoholic extracts of “espinheira santa” (Maytenus aquifolium Martius, Celastraceae) leaves.J. Braz. Chem. Soc.200415458258610.1590/S0103‑50532004000400022
     [Google Scholar]
  70. NieroR. Faloni de AndradeS. Cechinel FilhoV. A review of the ethnopharmacology, phytochemistry and pharmacology of plants of the Maytenus genus.Curr. Pharm. Des.201117181851187110.2174/13816121179639102921554223
     [Google Scholar]
  71. NieroR. MoserR. BusatoA.C.B. FilhoV.C. YunesR.A. ReisA. A comparative chemical study of Maytenus ilicifolia mart. reiss and Maytenus robusta reiss (Celastraceae).Z. Naturforsch. C J. Biosci.2001561-215816210.1515/znc‑2001‑1‑22411302207
     [Google Scholar]
  72. HuangY.Y. ChenL. MaG.X. XuX.D. JiaX.G. DengF.S. LiX.J. YuanJ.Q. A review on phytochemicals of the genus Maytenus and their bioactive studies.Molecules20212615456310.3390/molecules2615456334361712
     [Google Scholar]
  73. Gomes CoelhoR. Di StasiL.C. VilegasW. Chemical constituents from the infusion of Zollernia ilicifolia Vog. and comparison with Maytenus species.Z. Naturforsch. C J. Biosci.2003581-2475210.1515/znc‑2003‑1‑20812622225
     [Google Scholar]
  74. GonzalezF.G. PortelaT.Y. StippE.J. Di StasiL.C. Antiulcerogenic and analgesic effects of maytenus aquifolium, sorocea bomplandii and zolernia ilicifolia.J. Ethnopharmacol.2001771414710.1016/S0378‑8741(01)00268‑911483377
     [Google Scholar]
  75. AndradeF.D.P. VilegasW. Constituintes de sorocea bonplandii baillon.Rev Ciênc Farm199819129139
     [Google Scholar]
  76. TabachR. Duarte-AlmeidaJ.M. CarliniE.A. Pharmacological and toxicological study of Maytenus ilicifolia leaf extract Part II-clinical study (Phase I).Phytother. Res.201731692192610.1002/ptr.581628480515
     [Google Scholar]
  77. CarliniE.A. Frochten GartenM.L. Toxicologia clínica (Fase I) da espinheira-santa (Maytenus ilicifolia). In: Central de Medicamentos (Brazil). Estudo de ação antiúlcera gástrica de plantas brasileiras (Maytenus ilicifolia “espinheira-santa” e outras); ,19886773
     [Google Scholar]
  78. MeneguettiD.U.O. LimaR.A. da SilvaF.C. PassariniG.M. FacundoJ.B. PagottoR.C. MilitãoJ.S.L.T. FacundoV.A. Acute genotoxicity analysis in vivo of the aqueous extract of Maytenus guyanensis Amazonian chichuá.Rev. Bras. Farmacogn.201525216416910.1016/j.bjp.2015.03.003
     [Google Scholar]
  79. GutaD. MunthaliC.R.Y. KamanulaJ.F. MissanjoE. JenyaH. Socio-economic importance, abundance and phytochemistry of Jateorhiza palmata (Lam.) Miers, a medicinal plant in Nsanje, Malawi.Int. J. Sci. Res. Agricult. Sci.201633738310.12983/ijsras‑2016‑p0073‑0083
     [Google Scholar]
/content/journals/npj/10.2174/0122103155283762240213072144
Loading
Monteverdia ilicifolia as a Herbal Medicine for Treating Gastric Disorders: An Insight into its Quality Control
Natural Products Journal, The 15, E220224227340 (2025); https://doi.org/10.2174/0122103155283762240213072144
/content/journals/npj/10.2174/0122103155283762240213072144
/content/journals/npj/10.2174/0122103155283762240213072144
Loading

Data & Media loading...


  • Article Type:     Review Article
Keyword(s): Adulterants; chemical constituents; chromatography; friedelin; Maytenus ilicifolia; quality control

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test