Drug Delivery Letters - Volume 12, Issue 2, 2022

Tablet coating has evolved over the years, and today, there are various types of coating for the delayed release of a drug. Drugs can be enteric-coated to provide delayed release, protect the active pharmaceutical ingredients, minimize undesirable effects, and modify the pharmacokinetic properties of a drug, which will have clinical impacts. Certain types of drugs need to be entericcoated for various reasons, such as gastri Read More

Osteoporosis is a chronic, progressive bone condition that is most prevalent in postmenopausal women and the elderly population. An imbalance in the natural bone remodeling process, which is involved in the formation of bone and resorption, is responsible for osteoporosis, leading to bone fragility. It shows no clinical manifestation until a fracture takes place. Osteoporosis is a global epidemic that reduces the quality of life, i Read More

Parasitic infections are prime causes of morbidity and mortality worldwide. Significant progress has been made to cure these infections, such as discovering antiparasitic drugs, developing new formulation strategies, site-directed drug delivery, chemotherapy, etc. Synthetic drugs are perilous and have various side effects, leading to the development of drug resistance and loss of health. Herbal medicines are economical and g Read More

Background: Microsponge drug delivery systems comprise spherical and porous microspheres for prolonged topical drug delivery. These systems considerably reduce the undesirable side effects, offering improved patient compliance and reduced dosing frequency. Objective: The present study focused on developing topical controlled release preparations of microsponges-loaded gel of clarithromycin to cure bacterial skin infecti Read More

Background: Gallic acid is a natural phenolic compound found in several fruits and medicinal plants. It is reported to have several health-promoting effects, including antioxidant, antiinflammatory, antidiabetic, and antineoplastic properties in gastrointestinal, neuropsychological, metabolic, and cardiovascular disorders. Aims: The aim of the present work was to study the influence of formulation factors on the physicochemical pr Read More

Background: Obesity, considered a complex condition, is the fastest-growing public health concern worldwide. Its treatment is limited due to the side effects of pharmacological options available, outweighing their benefits. Aim: The present study aims to formulate a novel biodegradable formulation of exenatide for direct brain delivery through the nasal route. Methods: To formulate exenatide loaded poly (lactide-co-glyco Read More