Current Topics in Medicinal Chemistry - Volume 24, Issue 22, 2024

Phyllanthus emblica, popularly mentioned as amla or Indian gooseberry, has attracted a lot of interest lately because of its varied phytochemical makeup and related pharmacological properties. The phytochemistry, historical applications, bioactive makeup, and pharmacological properties of Phyllanthus emblica fruits are all summarised in this paper. This review emphasises the rich phytochemical profile of Phyllanthus emblic Read More

Neurological disorders, characterized by oxidative stress (OS) and inflammation, have become a major global health concern. Redox reactions play a vital role in regulating the balance of the neuronal microenvironment. Specifically, the imbalance leads to a significant weakening of the organism's natural defensive mechanisms. This, in turn, causes the development of harmful oxidative stress, which plays a crucial role i Read More

Introduction Toxoplasmosis is a worldwide distributed zoonosis caused by Toxoplasma gondii (T. gondii), an obligate intracellular protozoan. The infection in immunocompetent hosts usually progresses with mild or no symptoms. However, in immunocompromised individuals, this disease can cause severe or fatal symptoms. Methods Sulfadiazine and pyrimethamine are two drugs used as standard therapies for human toxopla Read More

Background The synthesis of nanoparticles using the principle of green chemistry has achieved huge potential in nanomedicine. Here, we report the synthesis of silver nanoparticles (AgNPs) employing garlic essential oil (GEO) due to wide applications of GEO in the biomedical and pharmaceutical industry. Objective This study aimed to synthesise garlic essential oil-assisted silver nanoparticles and present their anti Read More