Current Radiopharmaceuticals - Online First

Introduction The ideal [131I]Sodium Iodide activity for intermediate-risk thyroid cancer treatment is still uncertain. The objective of this study is to compare the biochemical responses to radioiodine therapy (RIT) of intermediate-risk thyroid cancer patients administered [131I]Sodium Iodide at doses of 3700 MBq (100 mCi) and 5550 MBq (150 mCi). Methods A retrospective study was conducted by reviewing the medical records Read More

RNA-binding proteins (RBPs) regulate gene expression at the post-transcriptional level and are important factors in cancer progression and response to various therapeutic strategies. Radioresistance, an obstacle caused due to various intrinsic and extrinsic factors, remains a major hindrance in the treatment of cancer and could lead to tumor recurrence. Though research is being conducted on the cause and associ Read More

Introduction A promising material used in radiation synovectomy of small joints is hydroxyapatite, labeled with 177Lu. During the design and production of radiopharmaceuticals, the condition of the radiolabeling process directly influences the radiochemical yield and consequently the quality of the final product so this process necessitates precise optimization. Methods In this investigation, a central composite design ba Read More

Introduction Radiation-induced damage to the hematopoietic and gastrointestinal systems, especially the intestine, is a major concern for individuals exposed to whole-body 
radiation during an accident. Resveratrol has shown potential in mitigating radiation-induced toxicity, but its efficacy may be limited by its low bioavailability. In this study, we aimed 
to evaluate the effectiveness of resveratrol-loaded polymeric-b Read More