Current Protein and Peptide Science - Volume 14, Issue 3, 2013

Elevated blood pressure or hypertension is one of the fastest growing health problems worldwide. Although the etiology of essential hypertension has a genetic component, dietary factors play an important role. With the high costs and adverse side-effects associated with synthetic antihypertensive drugs and the awareness of the link between diet and health there has been increased focus on identification of food c Read More

Marine organisms have long been recognized as rich source of bioactive material with numerous health benefit effects. Among bioactive material, proteins and peptides derived from marine organisms have been shown to inhibit the development of neuro-degenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. The neuro-protective action of protein and peptide seem to be mediate Read More

Marine organisms are important sources for bioactive molecules that have been developed into treatments for various diseases. The unusual marine environment associated with chemical diversity constitutes an actually unlimited resource of new active substances in the field of the development of bioactive products. In this review, the molecular diversity of marine peptides is described as well as information about t Read More

Recently, there has been a growing in alternative prevents and therapies of marine organisms for metabolic syndrome. Marine-derived bioactive peptides attracted extensive interest due to their numerous health beneficial effects including antioxidant, antihypertensive, anti-diabetes, anti-obesity. The bioactive peptides may provide novel therapeutic applications for the prevention of metabolic syndrome. The facts summar Read More

Bioactive peptides derived from marine organisms are the focus of current studies because of their numerous health beneficial effects. They exert various biological roles, one of the most crucial of which is the antioxidant effect. Reverse relationship between antioxidant intake and diseases has been approved through plenty of studies. Antioxidant activity of marine peptides can be attributed to in vitro and in vivo free radical sca Read More

The development of more effective antithrombotic agents with reduced side risk is necessary for the prevention of thromboembolic events. In recent years, bioactive peptides derived from food proteins have received considerable attention because of their numerous healths beneficial. Based on their amino acids sequences these peptides can exhibit various biological activities including, antihypertensive, antioxidative a Read More

Despite the success in antimicrobial development, the rapid emergence of pathogenic bacteria resistance to conventional antibiotics calls for an increased focus on the purification and characterization of new antimicrobials. Antimicrobial peptides (AMPs) are promising candidates in future therapeutics. In addition to their broad array of antimicrobial activity, these peptides show multi advent function to human health. The Read More

Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically microalgae, cyanobacteria and seaweed. The structural characteristics of these peptides include various unusual amino acid residues, which may be responsible for their properties. Moreover, protein hydrolysates formed by the enzymatic digestion o Read More

Spinal cord injury (SCI) is accompanied by intractable pain as well as loss of motor and visceral control. As part of an overall strategy in patient rehabilitation and improvement in quality of life, pain management is crucial. Interestingly, SCI patients report pain below the level of injury that has characteristics of neuropathic-type pain. Preclinical studies suggest that a key substrate that underlies the symptoms of neuropathic Read More

Bioactive peptides obtained from marine species and marine by-products are showing these days a great interest in nutraceutical and pharmaceutical applications due to their wide range of biological activities. This mini-review focuses on the potential of marine peptides to be used as appetite suppressive molecules in the prevention and/or in the treatment of obesity syndrome. An important and promising aspect in Read More

Among bioactive peptides derived from aquatic protein, those with ACE inhibitory activity are receiving special attention. This paper presented an overview of ACE inhibitory peptides derived from aquatic proteins, and the peptide sources were listed. The structure-activity relationship and mechanism of action of ACE inhibitory peptides were also discussed. Finally, the antihypertensive effects of ACE inhibitory peptides deriv Read More