Current Organocatalysis - Volume 4, Issue 3, 2017

Background: 2-Substituted-1,3-benzothiazoles, 1,3-benzimidazoles and 1,3-benzoxazoles are one of the important classes of bicycle hetero-compounds because these moieties can serve as unique and versatile scaffolds for experimental drug design. Among these herocycles, 1,3- benzothiazole derivatives have attracted considerable attention in the research area of synthetic as well as pharmaceutical chemistry b Read More

Background: Quinolines are one of the most popular N-heteroaromatic compounds incorporated into the structures of many pharmaceuticals. The classical methods for the synthesis of quinoline derivatives include Skraup, Doebner–Von Miller, Conrad–Limbach, Combes, and Pfitzinger quinoline syntheses but the best-known method for the preparation of quinolines is Friedlander quinoline synthesis. A number of methods have be Read More

Background: Carbonyl compounds are one of the most important starting materials used in pharmaceutical and industries. Due to their high demand, a vast number of efficient and aerobic oxidation methods have been developed using suitable oxidizing agents or catalyst. Using cheaper starting materials and efficient methods which are more favorable are very important in terms of economic and environmental view poi Read More

Background: The biopolymer-containing hybrid composite materials of silica have drawn attention owing to their promising properties and biocompatibility with living matter. Silica component in such hybrids is responsible for the properties like temperature and mechanical resistance, porosity, while the biopolymer offers extra functionality and framework to the hybrid matrices. This work is devoted to selective C-H bon Read More

Background: Although, Wittig reaction is mainly reported with aldehydes and phorphorus ylides, unfortunately, aldehyde oxidation mainly drops the efficiency of the reaction trailed by the decomposition or polymerization. There are several one-pot methods that have been testified to achieve an efficient Wittig reaction, but these protocols mainly hurt due to the requirement of toxic, oxidizing mediators and the inevitability of the Read More