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- Volume 10, Issue 3, 2023
Current Organocatalysis - Volume 10, Issue 3, 2023
Volume 10, Issue 3, 2023
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Organocatalytic C-H Bond Functionalizations for the Synthesis of Heterocycles
More LessOrganocatalysis is an important and rapidly growing area for the synthesis of various organic molecules. Because of the inherent non-metal properties, mild reaction conditions, and broad functional group tolerance, the use of small organic compounds encoding and converting another organic component has developed into a remarkable process. C-H activation reactions, on the other hand, have already emerged as a p Read More
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Recent Progress in Palladium Catalysed Sustainable Synthesis of Heterocycles
Authors: Debasree Saha and Chhanda MukhopadhyayBackground: Palladium metal has been extensively used in the synthesis of organic molecules for the last few decades. Heterocyclic ring synthesis being a significant part of organic synthesis, transition metal catalysis, especially catalysis by palladium, has been actively employed in heterocyclic synthesis. However, since palladium is an expensive metal, there has always been an urge to reuse or recycle the palladium catalyst to Read More
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Water Mediated Green Method Synthesis of Bioactive Heterocyclic Reported Between 2012-2021 Accelerated by Microwave Irradiation: A Decennary Update
Authors: Kantharaju Kamanna and Yamanappagouda AmaregoudaThe diverse field of chemistry demands various greener pathways in our quest to maintain sustainability. The utilization of energy inputs (mechanochemistry, ultrasound, or microwave irradiation), photochemistry, and greener reaction media being applied to organic synthesis are the key trends in the greener and sustainable process development in the current synthetic chemistry. These strategic methods aim to addr Read More
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Review on the Synthesis of Bio-Active Spiro-Fused Heterocyclic Molecules
Authors: Geetika Patel, Ashok Raj Patel, Sameera Kheti, Parimal K. Sao, Gargee Rathore and Subhash BanerjeeBackground: The spiro entity and heterocyclic scaffolds are decorated with a variety of biological and pharmaceutical properties. Therefore, the fusion of spiro compounds with individual moieties. Thus, the designing and expansion of the methods for the synthesis of various spiro-fused heterocyclic scaffolds are significantly important for synthetic organic chemistry. Methods: A variety of spiro-fused heterocyclic scaffolds Read More
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A Decenary Update on Metal Oxide Nanoparticles as a Heterogeneous Greener Catalyst for the Synthesis of Bioactive Heterocycles
Authors: Kantharaju Kamanna and Krishnappa B BadigerIn recent years, heterocycle derivatives have emerged as promising molecules, and have exhibited remarkable pharmacological applications. The statistical data analysis of the presently available drug molecules in the market has revealed that more than 70% of the drug candidates are derived from the heterocycles. Various synthetic protocols have been established employing a wide range of catalysts and reaction con Read More
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Greener Approaches Towards 1,4–Benzothiazine Synthesis: Recent Updates and Outlook
Authors: Suchandra Bhattacharya and Basudeb BasuHeterocyclic moieties are ubiquitous in nature and the exploration of heterocyclic chemistry goes centuries back, which have coalesced into the invention of greener methodologies towards the synthesis of heterocycles of potential uses. Benzothiazine is an important class of heterocyclic molecule, in which a benzene ring is fused with a six–member N, S containing ring. Amongst the three possible isomers, 1,4–benzothiazi Read More
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Greener Approaches for Synthesis of Bioactive Thiadiazole Scaffolds
Thiadiazole is a paradigm of five membered heterocyclic compound that contains two nitrogens and one sulphur as heteroatoms with molecular formula C2H2N2S. Thiadiazole is mainly present in four isomeric forms such as 1,2,3-thiadiazole, 1,2,4-thiadiazole, 1,2,5-thiadiazole and 1,3,4-thiadiazole. Out of these isomers, 1,3,4-thiadiazole has attracted remarkable attention in the field of medicinal chemistry. Some of the d Read More
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A Greener Synthetic Approach to Tetrazoles via Multicomponent Reactions
By Devalina RayThe synthesis of heterocyclic compounds has drawn considerable attention in the scientific community due to their existence in the majority of medicinal & pharmaceutically important compounds as well as natural products. Among them, the remarkable existence of tetrazoles has been realized in several commercially available drugs. In this regard, various synthetic protocols to access tetrazoles have been developed to Read More
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Liquid Membranes in Catalysis
Authors: Muhammad W. Ashraf and M. Amin Mir
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