Current Organic Chemistry - Volume 17, Issue 10, 2013

Synthesis of the functionalized silica-coated magnetic nanoparticles (Si-MNPs) was achieved with organic/inorganic hybrids and approached for high throughput biomolecular separation. To increase the reactivity between biomolecules and Si-MNPs, organic/ inorganic hybrid functionalization has been obtained through the coupling of organosilanes, having various organic residues, with free sianol groups of the silica surfaces. This Read More

Our aim was to investigate the influence of magnetic nanoparticles of Fe3O4/oleic acid - core/shell on the adherence to cellular and inert substrata of clinical fungal using direct and inverted optic microscopy and Confocal Laser Scanning Microscopy (CLSM). The biofilm development ability varied with the tested species (C. albicans>C. tropicalis>C. glabrata>S. cerevisiae>C. krusei>C. famata), its intensity being correlated with earl Read More

A simple method for the synthesis of magnetic hollow silica microspheres is reported. Magnetic hollow silica was obtained after pretreating via precipitation method of the dextran template microspheres with magnetite. Silica shell was obtained from Na2SiO3. After thermal decomposition of the dextran template, the magnetic silica shells remained intact, as demonstrated by SEM and no evidence of dextran remnants was fo Read More

In recent few decades, magnetic nanoparticles have emerged as an ideal support for catalysts because of their easy preparation and functionalization, low toxicity and price. Magnetic nanoparticles-supported catalysts have been used to catalyze lots of organic reactions, including C-C bond form reaction, hydrogenation reaction, oxidation reaction, phase-transfer reaction and dihydroxylation reaction. They can be r Read More

A novel Pd(II) organometallic catalyst bonded to magnetic SiO2@Fe3O4 support was synthesized by coordinating Pd(II) with the PPh2-ligand originally grafted onto the silica layer covering the Fe3O4 microspheres. Owing to the high dispersion of Pd(II) active sites, the as-prepared Pd-PPh2-SiO2@Fe3O4 catalyst exhibited comparable activities and selectivities with the PdCl2(PPh3)2 homogeneous catalyst in various wat Read More

The adaptation of marine organisms to a wide range of environmental conditions in the specific environment (temperature, salinity, tides, pressure, radiation, light, etc.) has made them an enormous reservoir of interesting biological material for both basic research and biotechnological improvements. Both this evolutionary richness and the knowledge of enzyme action including the comprehension of interactive effects o Read More

The present review deals with the C-prenylation of phenolic compounds, the topic has even gained a considerable scientific attention but still poorly described in the literature. A brief introduction on natural sources of C-prenylated phenolics is highlighted in the first lines, underlining also few of the recent studies on identification, biological applications and biosynthesis of mainly C-prenylflavonoids and -xanthones along with othe Read More

The synthesis and characterization of the first rigid fused porphyrin-phthalocyanine hetero-dyad with two different metals is reported; was based on porphyrin's dienophile features in Diels-Alder reactions. This synthetic procedure represents a new approach for the synthesis of extended systems based on tetrapyrrolic macrocycles.

Catalytic amounts of NaNO2 are able to successfully promote the reaction between 1,4-hydroquinone and methanol under acidic conditions, affording selectively the corresponding mequinol in excellent isolated yields. According to the proposed reaction mechanism, the semi-quinone intermediate, generated in situ from the corresponding hydroquinone by NO2 oxidation, is the real reactive species, undergoing nucleop Read More

The synthesis of novel acyclic pyrimidine nucleoside analogues with 1,2,3-triazole ring bound via ethylene spacer or directly to C-5 of pyrimidine ring has been reported. 1,4-Disubstituted 1,2,3-triazoles were synthesized by click chemistry approach using regioselective copper(I)-catalyzed 1,3-dipolar cycloaddition reaction between terminal alkyne and azido pyrimidines under both conventional (method A) and microwave (meth Read More

Following our previous studies, to affiliate selective pharmacophore in a single molecular entity, domino, ecologically benign, four hetero-component, single pot reaction has been carried out in (bmim)BF4 ionic liquid to structure a new class of compact heteronuclei. In a newly constructed heterocyclic Ugi adducts, quinoline was used as nitrogen source and benzothiazole as well as thiophene moieties were selec Read More