Current Nanomedicine - Volume 12, Issue 3, 2022

One of the major limitations to drug delivery at mucosal administration sites is the limited retention of the dose at the tissue surface. Bioadhesive delivery systems increase the residence time/retention of the dosage form at the application site. To retain the drug at the site of administration for improved absorption and ease of administration, the identification of polymer systems based on site-specific physiological conditions is i Read More

Nanoformulations are a novel method of administration of the drug, approved by the USFDA. These formulations are able to deliver the drug molecules to the target site more effectively and efficiently. So, this technology has found a vital role in cancer therapy. The nanoformulations can be of many types: Liposomes, Micelles, Nano-emulsions, Dendrimers, etc. Many studies have been done on nanoformulations and it is re Read More

Successful drug delivery with a carrier into the targeted organelles (nucleus, mitochondria, lysosomes, etc.) is vital for achieving effective disease treatment. Nanoparticle (NP) based drug delivery systems (NDDSs) depend on targeted delivery and are mainly focused on cellmembrane targeting. In this review, we summarize research on multifunctional NPs with organellespecific drug delivery. Different effective strategie Read More

Background: The current review focuses on ophthalmic nanogels, their applications, their benefits over traditional gels, and the challenges and opportunities of nanogels. The major goal is to investigate ophthalmic nanogels from preparation through characterization and how nanogels are the future of the ophthalmic drug delivery system compared to traditional gels, eye drops, and ointments. Objective: Because of the oph Read More

Background: Tobacco smoking is a major factor leading to cardiovascular diseases. About 48% of cardiovascular diseases occur due to cigarette smoking. Bupropion hydrochloride is a non-nicotine treatment for smoking cessation. The existing marketed formulation of bupropion has limitations, like low bioavailability and extensive first-pass metabolism. In order to boost the bioavailability and increase the brain biodistr Read More