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2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Background

Transvaginal and transabdominal ultrasonography has become a widely used investigative method in the diagnostic workup of endometriosis, as well as for the postoperative follow-up. The variety of lesions, the distorted anatomy caused by adhesions and the fibrosis process represent the main challenges of the ultrasound evaluation. Regarding the recurrence of endometriosis, the diagnostic criteria are being imprecise, being adjusted according to the development of ultrasound techniques.

Objective and Methods

To this study, extensive research has been performed interrogating PubMed, Embase and Web of Science databases to identify published research including patients with endometriosis who underwent surgery. Included patients had postoperative ultrasound investigations to detect evidence of endometriosis recurrence. The selected timeframe was 5 years. We conducted a literature review on ultrasound markers of endometriosis recurrence.

Results

In this analysis, 2023 patients from 9 studies were included. The recurrence rate detected was 17.26%. The postoperative treatment was different in the selected studies and they include the administration of progesterone, oral combined contraceptives, GnRh antagonists, aromatase inhibitors and intrauterine devices with prolonged release of progesterone.

Discussion

The recurrence rate is different in the selected studies as a result of the recurrence definition used by each author and the minimum dimension of the lesions, in case of the cystic pattern. Innovative techniques of differential diagnosis by ultrasound are proposed, one of them being the textural analysis performed by computer-aided diagnosis – CAD. In order to standardize the recommendations regarding imaging techniques, we propose an algorithm for following up with patients in the postoperative period.

Conclusion

The transabdominal or endovaginal ultrasound performed regularly represents a key factor to determine the recurrence of endometriosis in the postoperative period and the imaging reassessment is recommended to be performed at a 6-month interval.

© 2024 The Author(s). Published by Bentham Science Publisher. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2023-06-26
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References

  1. KennedyS. BergqvistA. ChapronC. D’HoogheT. DunselmanG. GrebR. HummelshojL. PrenticeA. SaridoganE. ESHRE guideline for the diagnosis and treatment of endometriosis.Hum. Reprod.200520102698270410.1093/humrep/dei13515980014
    [Google Scholar]
  2. DunselmanG.A.J. VermeulenN. BeckerC. Calhaz-JorgeC. D’HoogheT. De BieB. HeikinheimoO. HorneA.W. KieselL. NapA. PrenticeA. SaridoganE. SorianoD. NelenW. ESHRE guideline: Management of women with endometriosis.Hum. Reprod.201429340041210.1093/humrep/det45724435778
    [Google Scholar]
  3. MooreJ. CopleyS. MorrisJ. LindsellD. GoldingS. KennedyS. A systematic review of the accuracy of ultrasound in the diagnosis of endometriosis.Ultrasound Obstet. Gynecol.200220663063410.1046/j.1469‑0705.2002.00862.x12493057
    [Google Scholar]
  4. MartireF.G. ZupiE. LazzeriL. MorosettiG. ConwayF. CentiniG. SolimaE. PietropolliA. PiccioneE. ExacoustosC. Transvaginal ultrasound findings after laparoscopic rectosigmoid segmental resection for deep infiltrating endometriosis.J. Ultrasound Med.20214061219122810.1002/jum.1550532936475
    [Google Scholar]
  5. LazzeriL. Di GiovanniA. ExacoustosC. TostiC. PinzautiS. MalzoniM. PetragliaF. ZupiE. Preoperative and postoperative clinical and transvaginal ultrasound findings of adenomyosis in patients with deep infiltrating endometriosis.Reprod. Sci.20142181027103310.1177/193371911452252024532217
    [Google Scholar]
  6. ReidS. LuC. CasikarI. ReidG. AbbottJ. CarioG. ChouD. KowalskiD. CooperM. CondousG. Prediction of pouch of Douglas obliteration in women with suspected endometriosis using a new real-time dynamic transvaginal ultrasound technique: The sliding sign.Ultrasound Obstet. Gynecol.201341668569110.1002/uog.1230523001892
    [Google Scholar]
  7. GuerraA. DaraïE. OsórioF. SetúbalA. BendifallahS. LoureiroA. Thomassin-NaggaraI. Imaging of postoperative endometriosis.Diagn. Interv. Imaging20191001060761810.1016/j.diii.2018.11.00330770231
    [Google Scholar]
  8. BazotM. BharwaniN. HuchonC. KinkelK. CunhaT.M. GuerraA. ManganaroL. BuñeschL. KidoA. TogashiK. Thomassin-NaggaraI. RockallA.G. European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis.Eur. Radiol.20172772765277510.1007/s00330‑016‑4673‑z27921160
    [Google Scholar]
  9. ChamiéL.P. BlasbalgR. GonçalvesM.O.C. CarvalhoF.M. AbrãoM.S. de OliveiraI.S. Accuracy of magnetic resonance imaging for diagnosis and preoperative assessment of deeply infiltrating endometriosis.Int. J. Gynaecol. Obstet.2009106319820110.1016/j.ijgo.2009.04.01319467541
    [Google Scholar]
  10. IchikawaM. AkiraS. KasekiH. WatanabeK. OnoS. TakeshitaT. Accuracy and clinical value of an adhesion scoring system: A preoperative diagnostic method using transvaginal ultrasonography for endometriotic adhesion.J. Obstet. Gynaecol. Res.202046346647810.1111/jog.1419132003109
    [Google Scholar]
  11. ChamiéL.P. RibeiroD.M.F.R. RibeiroG.M.P.A.R. SerafiniP.C. Postoperative imaging findings after laparoscopic surgery for deeply infiltrating endometriosis.Abdom. Radiol.20204561847186510.1007/s00261‑020‑02434‑532030450
    [Google Scholar]
  12. MaisV. BraccoG.L. LittaP. GargiuloT. MelisG.B. Reduction of postoperative adhesions with an auto-crosslinked hyaluronan gel in gynaecological laparoscopic surgery: A blinded, controlled, randomized, multicentre study.Hum. Reprod.20062151248125410.1093/humrep/dei48816439505
    [Google Scholar]
  13. LucianoD.E. RoyG. LucianoA.A. Adhesion reformation after laparoscopic adhesiolysis: Where, what type, and in whom they are most likely to recur.J. Minim. Invasive Gynecol.2008151444810.1016/j.jmig.2007.09.01218262143
    [Google Scholar]
  14. PossoverM. Five-year follow-up after laparoscopic large nerve resection for deep infiltrating sciatic nerve endometriosis.J. Minim. Invasive Gynecol.201724582282610.1016/j.jmig.2017.02.02728445777
    [Google Scholar]
  15. ExacoustosC. ZupiE. AmadioA. AmorosoC. SzabolcsB. RomaniniM.E. ArduiniD. Recurrence of endometriomas after laparoscopic removal: Sonographic and clinical follow-up and indication for second surgery.J. Minim. Invasive Gynecol.200613428128810.1016/j.jmig.2006.03.00216825067
    [Google Scholar]
  16. CeccaroniM. BounousV.E. ClariziaR. MautoneD. MabroukM. Recurrent endometriosis: A battle against an unknown enemy.Eur. J. Contracept. Reprod. Health Care201924646447410.1080/13625187.2019.166239131550940
    [Google Scholar]
  17. GuoS.W. Recurrence of endometriosis and its control.Hum. Reprod. Update200915444146110.1093/humupd/dmp00719279046
    [Google Scholar]
  18. TandoiI. SomiglianaE. RipariniJ. RonzoniS. Vigano’P. CandianiM. High rate of endometriosis recurrence in young women.J. Pediatr. Adolesc. Gynecol.201124637637910.1016/j.jpag.2011.06.01221906976
    [Google Scholar]
  19. StrattonP. SinaiiN. SegarsJ. KoziolD. WesleyR. ZimmerC. WinkelC. NiemanL.K. Return of chronic pelvic pain from endometriosis after raloxifene treatment: A randomized controlled trial.Obstet. Gynecol.20081111889610.1097/01.AOG.0000297307.35024.b518165396
    [Google Scholar]
  20. ParazziniF. BertulessiC. PasiniA. RosatiM. Di StefanoF. ShonauerS. VicinoM. AguzzoliL. TrossarelliG.F. MassobrioM. BraccoG. PerinoA. MoroniS. BerettaP. Determinants of short term recurrence rate of endometriosis.Eur. J. Obstet. Gynecol. Reprod. Biol.2005121221621910.1016/j.ejogrb.2004.11.03316054965
    [Google Scholar]
  21. HidariT. HirataT. ArakawaT. KogaK. NeriishiK. FukudaS. NakazawaA. NagashimaN. MaS. SunH. TakamuraM. HaradaM. HirotaY. Wada-HiraikeO. FujiiT. OsugaY. Contralateral ovarian endometrioma recurrence after unilateral salpingo-oophorectomy.BMC Womens Health20191915910.1186/s12905‑019‑0760‑z31046768
    [Google Scholar]
  22. YamanakaA. HadaT. MatsumotoT. KannoK. ShiraneA. YanaiS. NakajimaS. EbisawaK. OtaY. AndouM. Effect of dienogest on pain and ovarian endometrioma occurrence after laparoscopic resection of uterosacral ligaments with deep infiltrating endometriosis.Eur. J. Obstet. Gynecol. Reprod. Biol.2017216515510.1016/j.ejogrb.2017.07.01428728071
    [Google Scholar]
  23. SeoJ.W. LeeD.Y. YoonB.K. ChoiD. The age-related recurrence of endometrioma after conservative surgery.Eur. J. Obstet. Gynecol. Reprod. Biol.2017208818510.1016/j.ejogrb.2016.11.01527894033
    [Google Scholar]
  24. ChandraA. RhoA.M. JeongK. YuT. JeonJ.H. ParkS.Y. LeeS.R. MoonH.S. ChungH.W. Clinical experience of long-term use of dienogest after surgery for ovarian endometrioma.Obstet. Gynecol. Sci.201861111111710.5468/ogs.2018.61.1.11129372157
    [Google Scholar]
  25. LeeS.R. YiK.W. SongJ.Y. SeoS.K. LeeD.Y. ChoS. KimS.H. Efficacy and safety of long-term use of dienogest in women with ovarian endometrioma.Reprod. Sci.201825334134610.1177/193371911772582029161960
    [Google Scholar]
  26. CandianiM. OttolinaJ. SchimberniM. TandoiI. BartiromoL. FerrariS. Recurrence rate after “one-step” CO2 fiber laser vaporization versus cystectomy for ovarian endometrioma: A 3-year follow-up study.J. Minim. Invasive Gynecol.202027490190810.1016/j.jmig.2019.07.02731377455
    [Google Scholar]
  27. Del FornoS. CofanoM. Degli EspostiE. ManzaraF. LenziJ. RaimondoD. ArenaA. ParadisiR. CasadioP. SeracchioliR. Long-term medical therapy after laparoscopic excision of ovarian endometriomas: Can we reduce and predict the risk of recurrence?Gynecol. Obstet. Invest.2021861-217017610.1159/00051431033849018
    [Google Scholar]
  28. TanejaA. KaurS. SoniR.K. BhanupriyaR. KaurJ. SinglaL. Evaluating the efficacy of levonorgestrel intrauterine system and danazol for relief of postoperative pain in endometriosis.J. Clin. Diagn. Res.2017111012
    [Google Scholar]
  29. KecksteinJ. SaridoganE. UlrichU.A. SillemM. OppeltP. SchweppeK.W. KrentelH. JanschekE. ExacoustosC. MalzoniM. MuellerM. RomanH. CondousG. FormanA. JansenF.W. BokorA. SimedreaV. HudelistG. The #Enzian classification: A comprehensive non‐invasive and surgical description system for endometriosis.Acta Obstet. Gynecol. Scand.202110071165117510.1111/aogs.1409933483970
    [Google Scholar]
  30. MeulemanC. TomassettiC. D’HooreA. Van CleynenbreugelB. PenninckxF. VergoteI. D’HoogheT. Surgical treatment of deeply infiltrating endometriosis with colorectal involvement.Hum. Reprod. Update201117331132610.1093/humupd/dmq05721233128
    [Google Scholar]
  31. MuziiL. MaranaR. CaruanaP. CatalanoG.F. MarguttiF. PaniciP.B. Postoperative administration of monophasic combined oral contraceptives after laparoscopic treatment of ovarian endometriomas: A prospective, randomized trial.Am. J. Obstet. Gynecol.2000183358859210.1067/mob.2000.10681710992178
    [Google Scholar]
  32. SeracchioliR. MabroukM. FrascàC. ManuzziL. SavelliL. VenturoliS. Long-term oral contraceptive pills and postoperative pain management after laparoscopic excision of ovarian endometrioma: A randomized controlled trial.Fertil. Steril.201094246447110.1016/j.fertnstert.2009.03.08319442968
    [Google Scholar]
  33. GrandiG. BarraF. FerreroS. SileoF.G. BertucciE. NapolitanoA. FacchinettiF. Hormonal contraception in women with endometriosis: A systematic review.Eur. J. Contracept. Reprod. Health Care2019241617010.1080/13625187.2018.155057630664383
    [Google Scholar]
  34. RomanH. VassilieffM. GourcerolG. SavoyeG. LeroiA.M. MarpeauL. MichotF. TuechJ.J. Surgical management of deep infiltrating endometriosis of the rectum: Pleading for a symptom-guided approach.Hum. Reprod.201126227428110.1093/humrep/deq33221131296
    [Google Scholar]
  35. JohnsonN.P. HummelshojL. AdamsonG.D. KecksteinJ. TaylorH.S. AbrãoM.S. BushD. KieselL. TamimiR. Sharpe-TimmsK.L. RombautsL. GiudiceL.C. World Endometriosis Society consensus on the classification of endometriosis.Hum. Reprod.201732231532410.1093/humrep/dew29327920089
    [Google Scholar]
  36. GiudiceL.C. Endometriosis.N. Engl. J. Med.2010362252389239810.1056/NEJMcp100027420573927
    [Google Scholar]
  37. BianchiP.H.M. PereiraR.M.A. ZanattaA. AlegrettiJ.R. MottaE.L.A. SerafiniP.C. Extensive excision of deep infiltrative endometriosis before in vitro fertilization significantly improves pregnancy rates.J. Minim. Invasive Gynecol.200916217418010.1016/j.jmig.2008.12.00919249705
    [Google Scholar]
  38. AlKudmaniB. GatI. BuellD. SalmanJ. ZohniK. LibrachC. SharmaP. In Vitro fertilization success rates after surgically treated endometriosis and effect of time interval between surgery and in vitro fertilization.J. Minim. Invasive Gynecol.20182519910410.1016/j.jmig.2017.08.64128807807
    [Google Scholar]
  39. BreteauP. Chanavaz-LacherayI. RubodC. TurckM. SanguinS. PopI. ReschB. RomanH. Pregnancy rates after surgical treatment of deep infiltrating endometriosis in infertile patients with at least 2 previous in vitro fertilization or intracytoplasmic sperm injection failures.J. Minim. Invasive Gynecol.20202751148115710.1016/j.jmig.2019.08.03231518714
    [Google Scholar]
  40. SurreyE.S. SchoolcraftW.B. Does surgical management of endometriosis within 6 months of an in vitro fertilization-embryo transfer cycle improve outcome?J. Assist. Reprod. Genet.200320936537010.1023/A:102542902761014531647
    [Google Scholar]
  41. ȘtefanR.A. ȘtefanP.A. MihuC.M. CsutakC. MelincoviciC.S. CriviiC.B. MaluțanA.M. HîțuL. LeboviciA. Ultrasonography in the differentiation of endometriomas from hemorrhagic ovarian cysts: The role of texture analysis.J. Pers. Med.202111761110.3390/jpm1107061134203314
    [Google Scholar]
  42. LupeanR.A. ȘtefanP.A. CsutakC. LeboviciA. MăluțanA.M. BuigaR. MelincoviciC.S. MihuC.M. Differentiation of endometriomas from ovarian hemorrhagic cysts at magnetic resonance: The role of texture analysis.Medicina2020561048710.3390/medicina5610048732977428
    [Google Scholar]
  43. LupeanR.A. ȘtefanP.A. OanceaM.D. MăluțanA.M. LeboviciA. PușcașM.E. CsutakC. MihuC.M. Computer tomography in the diagnosis of ovarian cysts: The role of fluid attenuation values.Healthcare20208439810.3390/healthcare804039833066370
    [Google Scholar]
  44. PascoalE. WesselsJ.M. Aas-EngM.K. AbraoM.S. CondousG. JurkovicD. EspadaM. ExacoustosC. FerreroS. GuerrieroS. HudelistG. MalzoniM. ReidS. TangS. TomassettiC. SinghS.S. Van den BoschT. LeonardiM. Strengths and limitations of diagnostic tools for endometriosis and relevance in diagnostic test accuracy research.Ultrasound Obstet. Gynecol.202260330932710.1002/uog.2489235229963
    [Google Scholar]
  45. NisenblatV. BossuytP.M.M. FarquharC. JohnsonN. HullM.L. Imaging modalities for the non-invasive diagnosis of endometriosis.Cochrane Libr.201622CD00959110.1002/14651858.CD009591.pub226919512
    [Google Scholar]
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  • Article Type:
    Review Article
Keyword(s): Diagnosis; Disease; Endometriosis; Postoperative; Recurrence; Ultrasound
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