Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Medical Imaging
  4. Volume 20, Issue 1
  5. Article
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
file format pdf download PDF
side by side viewer icon HTML

Abstract

Introduction

At present, early detection of the potential risk of atherosclerosis and prevention is of great significance to reduce the occurrence of stroke.

Aim

This study aims to explore the value of combining the wall shear stress measured by ultrasound vector flow imaging technique and sound touch elastography of common carotid artery in normal adults using the Mindray Resona 7 ultrasound system.

Methods

Forty volunteers (mean age 39.5 y, 23 females, 17 males) were divided into four groups according to their age. All volunteers underwent ultrasound carotid artery examination, and the values of wall shear stress and elasticity on the posterior wall of the common carotid artery were measured using advanced imaging functions, vector flow imaging technique, and sound touch elastography.

Results

Different cut-off values of wall shear stress were used to investigate the significance between two groups with corresponding sound touch elastography values. It can be seen that the statistical difference could be found when the mean wall shear stress was larger than 1.5 Pa approximately (statistical significance was defined when P < 0.05), and the sound touch elastography value was positively correlated with the wall shear stress value.

Conclusion

This study reveals that the combination of wall shear stress and sound touch elastography is an effective and feasible method for assessing carotid artery health. When the mean wall shear stress value is over 1.5 Pa, the corresponding sound touch elastography value increases significantly. The risk of atherosclerosis increases with the stiffness of blood vessel walls.

© 2024 The Author(s). Published by Bentham Open.
© 2024 The Author(s). Published by Bentham Open. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
Loading

Article metrics loading...

/content/journals/cmir/10.2174/1573405620666230327125840
2024-01-01
2024-11-23

  • From This Site

    /content/journals/cmir/10.2174/1573405620666230327125840
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

/deliver/fulltext/cmir/20/1/CMIM-20-e270323214999.html?itemId=/content/journals/cmir/10.2174/1573405620666230327125840&mimeType=html&fmt=ahah

References

  1. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.Lancet Neurol.20212010795820
     [Google Scholar]
  2. GoddiA. BortolottoC. RacitiM.V. FiorinaI. AianiL. MagistrettiG. SacchiA. TinelliC. CalliadaF. High-frame rate vector flow imaging of the carotid bifurcation in healthy adults: comparison with color doppler imaging.J. Ultrasound Med.201837922632275
     [Google Scholar]
  3. DongY. HongS. SongD. LiuM. GaoW. DuY. XuJ. DongF. Blood flow turbulence quantification of carotid artery with a high-frame rate vector flow imaging.J. Ultrasound Med.2022422427436
     [Google Scholar]
  4. ZhuY. XianX. WangZ. BiY. ChenQ. HanX. TangD. ChenR. Research progress on the relationship between atherosclerosis and inflammation.Biomolecules20188380
     [Google Scholar]
  5. NeremR.M. Vascular fluid mechanics, the arterial wall, and atherosclerosis.J. Biomech. Eng.19921143274282
     [Google Scholar]
  6. QiuY. DongY. MaoF. ZhangQ. YangD. ChenK. ShiS. ZuoD. TianX. YuL. High-frame rate vector flow imaging technique: Initial application in evaluating the hemodynamic changes of carotid stenosis caused by atherosclerosis.Front. Cardiovasc. Med.20218617391
     [Google Scholar]
  7. YounisH.F. Kaazempur-MofradM.R. ChanR.C. IsasiA.G. HintonD.P. ChauA.H. KimL.A. KammR.D. Hemodynamics and wall mechanics in human carotid bifurcation and its consequences for atherogenesis: investigation of inter-individual variation.Biomech. Model. Mechanobiol.2004311732
     [Google Scholar]
  8. OphirJ. AlamS.K. GarraB. KallelF. KonofagouE. KrouskopT. VargheseT. Elastography: ultrasonic estimation and imaging of the elastic properties of tissues.Proc. Inst. Mech. Eng. H19992133203233
     [Google Scholar]
  9. PruijssenJ.T. de KorteC.L. VossI. HansenH.H.G. Vascular shear wave elastography in atherosclerotic arteries: A systematic review.Ultrasound Med. Biol.202046921452163
     [Google Scholar]
  10. YiuB.Y.S. LaiS.S.M. YuA.C.H. Vector projectile imaging: time-resolved dynamic visualization of complex flow patterns.Ultrasound Med. Biol.201440922952309
     [Google Scholar]
  11. GatosI. DrazinosP. YarmenitisS. TheotokasI. ZoumpoulisP.S. Comparison of sound touch elastography, shear wave elastography and vibration-controlled transient elastography in chronic liver disease assessment using liver biopsy as the “reference standard”.Ultrasound Med. Biol.2020464959971
     [Google Scholar]
  12. ZhangL. DongY-J. ZhouJ-Q. JiaX-H. LiS. ZhanW-W. Similar reproducibility for strain and shear wave elastography in breast mass evaluation: A prospective study using the same ultrasound system.Ultrasound Med. Biol.2020464981991
     [Google Scholar]
  13. DuY. GoddiA. BortolottoC. ShenY. Dell’EraA. CalliadaF. ZhuL. Wall shear stress measurements based on ultrasound vector flow imaging: Theoretical studies and clinical examples.J. Ultrasound Med.202039816491664
     [Google Scholar]
  14. PoloniS. BozzettoM. DuY. AianiL. GoddiA. FiorinaI. RemuzziA. Velocity vector comparison between vector flow imaging and computational fluid dynamics in the carotid bifurcation.Ultrasonics2023128106860
     [Google Scholar]
  15. DuY. DingH. HeL. YiuB.Y.S. DengL. YuA.C.H. ZhuL. Quantitative blood flow measurements in the common carotid artery: A comparative study of high-frame-rate ultrasound vector flow imaging, pulsed wave doppler, and phase contrast magnetic resonance imaging.Diagnostics (Basel)2022123690
     [Google Scholar]
  16. QiuY. YangD. ZhangQ. ChenK. DongY. WangW-P. V Flow technology in measurement of wall shear stress of common carotid arteries in healthy adults: Feasibility and normal values.Clin. Hemorheol. Microcirc.2020744453462
     [Google Scholar]
  17. ZamaniM. SkagenK. ScottH. RussellD. SkjellandM. Advanced ultrasound methods in assessment of carotid plaque instability: a prospective multimodal study.BMC Neurol.202020139
     [Google Scholar]
  18. FriedmanM.H. DetersO.J. BargeronC.B. HutchinsG.M. MarkF.F. Shear-dependent thickening of the human arterial intima.Atherosclerosis1986602161171
     [Google Scholar]
  19. GnassoA. IraceC. CaralloC. De FranceschiM.S. MottiC. MattioliP.L. PujiaA. In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis.Stroke1997285993998
     [Google Scholar]
  20. CaralloC. LuccaL.F. CiameiM. TucciS. de FranceschiM.S. Wall shear stress is lower in the carotid artery responsible for a unilateral ischemic stroke.Atherosclerosis20061851108113
     [Google Scholar]
  21. GiddensD.P. ZarinsC.K. GlagovS. The role of fluid mechanics in the localization and detection of atherosclerosis.J. Biomech. Eng.19931154B588594
     [Google Scholar]
  22. GnassoA. CaralloC. IraceC. SpagnuoloV. De NovaraG. MattioliP.L. PujiaA. Association between intima-media thickness and wall shear stress in common carotid arteries in healthy male subjects.Circulation1996941232573262
     [Google Scholar]
  23. PedersenE.M. OyreS. AgerbaekM. KristensenI.B. RinggaardS. BoesigerP. PaaskeW.P. Distribution of early atherosclerotic lesions in the human abdominal aorta correlates with wall shear stresses measured in vivo .Eur. J. Vasc. Endovasc. Surg.1999184328333
     [Google Scholar]
  24. RenemanR.S. ArtsT. HoeksA.P.G. Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory.J. Vasc. Res.2006433251269
     [Google Scholar]
  25. ManbachiA. HoiY. WassermanB.A. LakattaE.G. SteinmanD.A. On the shape of the common carotid artery with implications for blood velocity profiles.Physiol. Meas.2011321218851897
     [Google Scholar]
  26. CorbanM.T. EshtehardiP. SuoJ. McDanielM.C. TimminsL.H. Rassoul-ArzrumlyE. MaynardC. MekonnenG. KingS. QuyyumiA.A. Combination of plaque burden, wall shear stress, and plaque phenotype has incremental value for prediction of coronary atherosclerotic plaque progression and vulnerability.Atherosclerosis20142322271276
     [Google Scholar]
  27. MalekA.M. AlperS.L. IzumoS. Hemodynamic shear stress and its role in atherosclerosis.JAMA19992822120352042
     [Google Scholar]
  28. EshtehardiP. BrownA.J. BhargavaA. CostopoulosC. HungO.Y. CorbanM.T. HosseiniH. GogasB.D. GiddensD.P. SamadyH. High wall shear stress and high-risk plaque: an emerging concept.Int. J. Cardiovasc. Imaging201733710891099
     [Google Scholar]
  29. LiuQ-Y. DuanQ. FuX-H. JiangM. XiaH-W. WanY-L. Wall shear stress can improve prediction accuracy for transient ischemic attack.World J. Clin. Cases201971827222733
     [Google Scholar]
/content/journals/cmir/10.2174/1573405620666230327125840
Loading
Feasibility Study of Combining Wall Shear Stress and Elastography to Assess the Vascular Status of Carotid Artery
Curr. Med. Imaging 20, E270323214999 (2024); https://doi.org/10.2174/1573405620666230327125840
/content/journals/cmir/10.2174/1573405620666230327125840
/content/journals/cmir/10.2174/1573405620666230327125840
Loading

Data & Media loading...


  • Article Type:     Research Article
Keyword(s): Atherosclerosis; Carotid artery; Elastography; Stroke; Ultrasound; Wall shear stress

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test