Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Medical Imaging
  4. Volume 20, Issue 1
  5. Article
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
file format pdf download PDF
side by side viewer icon HTML

Abstract

Objective

This study aimed to evaluate the diagnostic value of X-Map reconstruction based on Dual-Energy Computed Tomography (DECT) in acute ischemic stroke (AIS).

Methods

Sixty-six cases of suspected AIS patients hospitalized from November, 2021 to April, 2022 were retrospectively selected. DECT, Computed Tomography Perfusion imaging (CTP), Computed Tomography Angiography (CTA), and MRI were all performed within 24 hours after symptom onset. As the gold standard for diagnosing AIS, a total of 53 patients were diagnosed with AIS based on the diffusion-weighted imaging positive results in MRI. The Chi-square test was used to evaluate the diagnostic efficacy of AIS among X-Map, CTP, and CTA.

Results

In the 53 patients with confirmed ASI, a total of 72 lesions were detected, including in the frontal lobes (n=33), parietal lobes (n=7), temporal lobes (n=12), basal ganglia regions (n=12), thalamus (n=3), and pons (n=5). The case detection rate of X-Map for AIS was similar to that of CTP (p=0.151) but was significantly higher than that of CTA (p<0.001). In terms of diagnostic efficacy, among the total 66 patients enrolled, X-Map achieved a higher diagnostic sensitivity (85%) than CTP and CTA. However, CTP achieved the best diagnostic specificity (84.6%) and diagnostic accuracy (77.4%) among the diagnostic tools used.

Conclusion

X-Map provides a better or equal clinical value for the diagnosis of AIS as compared to CTA and CTP, respectively, highlighting its potential in clinical applications.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056294190240522113039
2024-01-01
2025-06-26

  • From This Site

    /content/journals/cmir/10.2174/0115734056294190240522113039
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
The full text of this item is not currently available.

References

  1. KatanM. LuftA. Global burden of stroke.Semin. Neurol.201838220821110.1055/s‑0038‑164950329791947
     [Google Scholar]
  2. Neurology Branch of Chinese Medical Association, Cerebrovascular Disease Group of Neurology Branch of Chinese Medical Association Guidelines for diagnosis and treatment of acute ischemic stroke in China 2014.Chin. J. Neurol.2015484
     [Google Scholar]
  3. HankeyG.J. Stroke.Lancet20173891006964165410.1016/S0140‑6736(16)30962‑X27637676
     [Google Scholar]
  4. KamedaK. UnoJ. OtsujiR. RenN. NagaokaS. MaedaK. IkaiY. GiH. Optimal thresholds for ischemic penumbra predicted by computed tomography perfusion in patients with acute ischemic stroke treated with mechanical thrombectomy.J. Neurointerv. Surg.201810327928410.1136/neurintsurg‑2017‑01308328600481
     [Google Scholar]
  5. ZhouL. ShenT. ChenX. Application of MR diffusion-weighted imaging in the diagnosis of hyperacute cerebral infarction.Chin. J. Radiol.2001
     [Google Scholar]
  6. SuzukiK. MoritaS. MasukawaA. MachidaH. UenoE. Utility of CT perfusion with 64-row multi-detector CT for acute ischemic brain stroke.Emerg. Radiol.20111829510110.1007/s10140‑010‑0905‑820842402
     [Google Scholar]
  7. NoguchiK. ItohT. NarutoN. TakashimaS. TanakaK. KurodaS. A novel imaging technique (X-Map) to identify acute ischemic lesions using noncontrast dual-energy computed tomography.J. Stroke Cerebrovasc. Dis.2017261344110.1016/j.jstrokecerebrovasdis.2016.08.02527639587
     [Google Scholar]
  8. YangY. YangJ. FengJ. WangY. Early diagnosis of acute ischemic stroke by brain computed tomography perfusion imaging combined with head and neck computed tomography angiography on deep learning algorithm.Contrast Media Mol. Imaging2022202211010.1155/2022/537358535615731
     [Google Scholar]
  9. WangY. PengY. WangT. LiH. ZhaoZ. GongL. PengB. The evolution and current situation in the application of dual-energy computed tomography: A bibliometric study.Quant. Imaging Med. Surg.202313106801681310.21037/qims‑23‑46737869341
     [Google Scholar]
  10. MangesiusS. JanjicT. SteigerR. HaiderL. RehwaldR. KnoflachM. WidmannG. GizewskiE. GramsA. Dual-energy computed tomography in acute ischemic stroke: State-of-the-art.Eur. Radiol.20213164138414710.1007/s00330‑020‑07543‑933319330
     [Google Scholar]
  11. WangJ. HuZ. YangS. LiuC. YangH. WangD. GuoF. Inflammatory cytokines and cells are potential markers for patients with cerebral apoplexy in intensive care unit.Exp. Ther. Med.20181621014102010.3892/etm.2018.621330116353
     [Google Scholar]
  12. ProvostC. SoudantM. LegrandL. Ben HassenW. XieY. SoizeS. BourcierR. BenzakounJ. EdjlaliM. BoulouisG. RaoultH. GuilleminF. NaggaraO. BracardS. OppenheimC. Magnetic resonance imaging or computed tomography before treatment in acute ischemic stroke.Stroke201950365966410.1161/STROKEAHA.118.02388230744542
     [Google Scholar]
  13. MurphyS.J.X. WerringD.J. Stroke: Causes and clinical features.Medicine202048956156610.1016/j.mpmed.2020.06.00232837228
     [Google Scholar]
  14. YousufuddinM. YoungN. Aging and ischemic stroke.Aging20191192542254410.18632/aging.10193131043575
     [Google Scholar]
  15. KarçaaltıncabaM. AktaşA. Dual-energy CT revisited with multidetector CT: Review of principles and clinical applications.Diagn. Interv. Radiol.201117318119420945292
     [Google Scholar]
  16. GuptaR. PhanC.M. LeideckerC. BradyT.J. HirschJ.A. NogueiraR.G. YooA.J. Evaluation of dual-energy CT for differentiating intracerebral hemorrhage from iodinated contrast material staining.Radiology2010257120521110.1148/radiol.1009180620679449
     [Google Scholar]
  17. LimJ. MagarikJ.A. FroehlerM.T. The CT‐defined hyperdense arterial sign as a marker for acute intracerebral large vessel occlusion.J. Neuroimaging201828221221610.1111/jon.1248429134723
     [Google Scholar]
  18. YuY.N. DingX.F. ZhangS. LouM. Thresholds of CT perfusion in predicting ischemic penumbra and infarct core in patients with acute ischemic stroke.J. Zhejiang Univ.201443171324616455
     [Google Scholar]
  19. PatilS. RossiR. JabrahD. DoyleK. Detection, diagnosis and treatment of acute ischemic stroke: Current and future perspectives.Front. Med. Technol.2022474894910.3389/fmedt.2022.74894935813155
     [Google Scholar]
  20. ShinoharaY. OhmuraT. IbarakiM. ItohT. SasakiF. SatoY. Non-contrast dual-energy CT using X-map for acute ischemic stroke: Region-specific comparison with simulated 120-kVp CT and diffusion-weighted MR images.Jpn. J. Radiol.202310.1007/s11604‑023‑01490‑337750952
     [Google Scholar]
  21. TaguchiK. ItohT. FuldM.K. FournieE. LeeO. NoguchiK. “X-Map 2.0” for edema signal enhancement for acute ischemic stroke using non–contrast-enhanced dual-energy computed tomography.Invest. Radiol.201853743243910.1097/RLI.000000000000046129543692
     [Google Scholar]
/content/journals/cmir/10.2174/0115734056294190240522113039
Loading
Diagnostic Value of X-Map Images Reconstructed by Plain Dual-Energy Computed Tomography Scans in Acute Ischemic Stroke
Curr. Med. Imaging 20, e15734056294190 (2024); https://doi.org/10.2174/0115734056294190240522113039
/content/journals/cmir/10.2174/0115734056294190240522113039
/content/journals/cmir/10.2174/0115734056294190240522113039
Loading

Data & Media loading...


  • Article Type:     Research Article
Keyword(s): CTA; Dual-energy; Magnetic resonance imaging; Stroke; X-Map; X-ray computer

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test