Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Medical Imaging
  4. Volume 20, Issue 1
  5. Article
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
file format pdf download PDF
side by side viewer icon HTML

Abstract

Background

Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare benign lesion that appears as a solid cystic renal lesion or complex renal cystic lesion on medical imaging. There are no definite imaging criteria for METSK diagnosis.

Case Presentation

We present a case of a solid cystic renal mass that was evaluated by contrast-enhanced ultrasound (CEUS) during an imaging workup. The patient underwent nephrectomy and histopathological confirmation of MESTK. The lesions showed hypoenhancement during the process. Quantitative perfusion analysis showed the septation of the solid cystic lesion to have lower peak enhancement with a longer rise time compared to the normal renal cortex.

Discussion

CEUS can visualize the microcirculation of the organ and reconstruction of the vessels. By providing a more detailed visualization of the microvessel, CEUS is a useful tool for further characterizing renal lesions that show indeterminate enhancement on CT. This study determined the time to peak to be shorter for the cancerous lesion than the normal renal cortex, while peak intensity did not differ between the cancerous lesion and the normal renal cortex.

Conclusion

Quantitative perfusion analysis of CEUS may be useful for differentiating benign and malignant solid cystic renal masses. Further investigation is needed to determine whether peak intensity is a useful parameter in differentiating benign and malignant solid cystic lesions of the kidney.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056244999231124113017
2024-01-01
2025-07-14

  • From This Site

    /content/journals/cmir/10.2174/0115734056244999231124113017
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
The full text of this item is not currently available.

References

  1. MichalM. SyrucekM. Benign mixed epithelial and stromal tumor of the kidney.Pathol. Res. Pract.1998194644544810.1016/S0344‑0338(98)80038‑19689654
     [Google Scholar]
  2. TatsuyaS. HirotakaA. YukiA. AkikoT. MasahiroH. ShigeoO. ShujiM. RyuichiM. MototsuguO. MasahiroJ. Radiologic features of mixed epithelial and stromal tumors of the kidney: Hyperattenuating on unenhanced computed tomography and T2-hypointensity on magnetic resonance imaging.Radiol. Case Rep.202116485886210.1016/j.radcr.2021.01.04833552340
     [Google Scholar]
  3. RübenthalerJ ČečatkaS FroelichM F StecheleM MarschnerC SabelB O BognerF SchnitzerM L OverhoffD Große HokampN StaehlerM SchwarzeV ClevertD Contrast-Enhanced Ultrasound (CEUS) for Follow-Up of Bosniak 2F Complex Renal Cystic Lesions-A 12-Year Retrospective Study in a Specialized European Center.Cancers (Basel).20201282170
     [Google Scholar]
  4. KaurR. JunejaM. MandalA.K. An overview of non-invasive imaging modalities for diagnosis of solid and cystic renal lesions.Med. Biol. Eng. Comput.202058112410.1007/s11517‑019‑02049‑z31748942
     [Google Scholar]
  5. ClevertD A MinaifarN WeckbachS JungE M StockK ReiserM StaehlerM Multislice computed tomography versus contrast-enhanced ultrasound in evaluation of complex cystic renal masses using the Bosniak classification system.Clin Hemorheol Microcirc.20081-81718
     [Google Scholar]
  6. AggarwalA. GoswamiS. DasC.J. Contrast-enhanced ultrasound of the kidneys: Principles and potential applications.Abdom. Radiol. (N.Y.)20224741369138410.1007/s00261‑022‑03438‑z35150315
     [Google Scholar]
  7. ErricoC. PierreJ. PezetS. DesaillyY. LenkeiZ. CoutureO. TanterM. Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging.Nature2015527757949950210.1038/nature1606626607546
     [Google Scholar]
  8. QuaiaE. BertolottoM. CioffiV. RossiA. BaratellaE. PizzolatoR. CovaM.A. Comparison of contrast-enhanced sonography with unenhanced sonography and contrast-enhanced CT in the diagnosis of malignancy in complex cystic renal masses.AJR Am. J. Roentgenol.200819141239124910.2214/AJR.07.354618806171
     [Google Scholar]
  9. ParkB.K. KimB. KimS.H. KoK. LeeH.M. ChoiH.Y. Assessment of cystic renal masses based on Bosniak classification: Comparison of CT and contrast-enhanced US.Eur. J. Radiol.200761231031410.1016/j.ejrad.2006.10.00417097844
     [Google Scholar]
  10. KhadilkarU N BasavaiahS H LaxmanP G TapadiaR RakeshB H Mixed epithelial and stromal tumor - A solid-cystic renal neoplasm undergoing malignant transformation: A rare case report.Indian J Pathol Microbiol.2018611123126
     [Google Scholar]
  11. LanD. QuH.C. LiN. ZhuX.W. LiuY.L. LiuC.L. The Value of Contrast-Enhanced Ultrasonography and Contrast-Enhanced CT in the Diagnosis of Malignant Renal Cystic Lesions: A Meta-Analysis.PLoS One2016115e015585710.1371/journal.pone.015585727203086
     [Google Scholar]
  12. NicolauC. BuneschL. SebastiaC. Renal complex cysts in adults: Contrast-enhanced ultrasound.Abdom. Imaging201136674275210.1007/s00261‑011‑9727‑821461960
     [Google Scholar]
  13. ChangE.H. ChongW.K. KasojiS.K. DaytonP.A. RathmellW.K. Management of Indeterminate Cystic Kidney Lesions: Review of Contrast-enhanced Ultrasound as a Diagnostic Tool.Urology20168711010.1016/j.urology.2015.10.00226483268
     [Google Scholar]
  14. AokiS. HattoriR. YamamotoT. FunahashiY. MatsukawaY. GotohM. YamadaY. HondaN. Contrast‐enhanced ultrasound using a time‐intensity curve for the diagnosis of renal cell carcinoma.BJU Int.2011108334935410.1111/j.1464‑410X.2010.09799.x21044245
     [Google Scholar]
  15. ShahzadK. SimmsM.S. ByassO. Evaluation of Contrast Enhanced Ultrasound for Investigation of Complex Cystic Renal Masses British Journal of Medical and Surgical Urology20114253258
     [Google Scholar]
  16. ChuaN. WolfeK. MehtaS. LiyanageS.H. Can contrast enhanced ultrasound differentiate benign cystic nephroma from malignant multicystic renal lesions? A case report.Urol. Case Rep.20202910107910.1016/j.eucr.2019.10107931867215
     [Google Scholar]
/content/journals/cmir/10.2174/0115734056244999231124113017
Loading
Quantitative Perfusion Analysis of Contrast-enhanced Ultrasound Might Help Differentiate Benign and Malignant Solid Cystic Lesions of the Kidney: A Case Report and Literature Review
Curr. Med. Imaging 20, e15734056244999 (2024); https://doi.org/10.2174/0115734056244999231124113017
/content/journals/cmir/10.2174/0115734056244999231124113017
/content/journals/cmir/10.2174/0115734056244999231124113017
Loading

Data & Media loading...


  • Article Type:     Case Report
Keyword(s): Benign; Contrast-enhanced ultrasound; Kidney; Mixed epithelial; Quantitative perfusion analysis; Solid-cystic lesion; Stromal tumor

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test