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Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Purpose

To evaluate the predictive value of 3.0T MRI Intravoxel Incoherent motion diffusion-weighted magnetic resonance imaging (IVIM-DWI) combined with texture analysis (TA) in the histological grade of rectal adenocarcinoma.

Methods

Seventy-one patients with rectal adenocarcinoma confirmed by pathology after surgical resection were collected retrospectively. According to pathology, they were divided into a poorly differentiated group (n=23) and a moderately differentiated group (n=48). The IVIM-DWI parameters and TA characteristics of the two groups were compared, and a prediction model was constructed by multivariate logistic regression analysis. ROC curves were plotted for each individual and combined parameter.

Results

There were statistically significant differences in D and D* values ​​between the two groups ( < 0.05). The three texture parameters SmallAreaEmphasis, Median, and Maximum had statistically significant differences between groups ( = 0.01, 0.004, 0.009, respectively). The logistic regression prediction model showed that D*, the median, and the maximum value were significant independent predictors, and the AUC of the regression prediction model was 0.860, which was significantly higher than other single parameters.

Conclusion

3.0T MRI IVIM-DWI parameters combined with TA can provide valuable information for predicting the histological grades of rectal adenocarcinoma one week before the operation.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-06-16

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/content/journals/cmir/10.2174/0115734056243265231024054017
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Intravoxel Incoherent Motion Diffusion-weighted Magnetic Resonance Imaging combined with Texture Analysis in Predicting the Histological Grades of Rectal Adenocarcinoma
Curr. Med. Imaging 20, e15734056243265 (2024); https://doi.org/10.2174/0115734056243265231024054017
/content/journals/cmir/10.2174/0115734056243265231024054017
/content/journals/cmir/10.2174/0115734056243265231024054017
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  • Article Type:     Research Article
Keyword(s): Degree of differentiation; Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging; Magnetic resonance imaging; Rectal adenocarcinoma; Rectal Carcinoma; Texture analysis

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